KEGG   REACTION: R05357
Entry
R05357                      Reaction                               

Name
amidinoproclavaminate amidinohydrolase
Definition
Guanidinoproclavaminic acid + H2O <=> Proclavaminic acid + Urea
Equation
Comment
pah gene
Reaction class
RC00024  C06657_C06658
RC00329  C00086_C06657
Enzyme
Pathway
rn00331  Clavulanic acid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00674  Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
Orthology
K12676  proclavaminate amidinohydrolase [EC:3.5.3.22]
Reference
1  [PMID:9614345]
  Authors
McGowan SJ, Bycroft BW, Salmond GP.
  Title
Bacterial production of carbapenems and clavams: evolution of beta-lactam antibiotic pathways.
  Journal
Trends Microbiol 6:203-8 (1998)
DOI:10.1016/S0966-842X(98)01251-7
Other DBs
RHEA: 17004

KEGG   RCLASS: RC00024
Entry
RC00024                     RClass                                 

Definition
N1a-N1b:*-C2c:C1b-C1b
Reactant pair
Related class
Reaction
Enzyme
2.1.4.1         2.1.4.2         2.1.4.3         3.5.3.1         
3.5.3.2         3.5.3.7         3.5.3.10        3.5.3.11        
3.5.3.17        3.5.3.20        3.5.3.22        3.5.3.23        
3.5.3.24        3.5.3.25
Pathway
rn00220  Arginine biosynthesis
rn00260  Glycine, serine and threonine metabolism
rn00330  Arginine and proline metabolism
rn00331  Clavulanic acid biosynthesis
rn00430  Taurine and hypotaurine metabolism
rn00472  D-Arginine and D-ornithine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Orthology
K00613  glycine amidinotransferase [EC:2.1.4.1]
K01476  arginase [EC:3.5.3.1]
K01480  agmatinase [EC:3.5.3.11]
K01484  succinylarginine dihydrolase [EC:3.5.3.23]
K04340  scyllo-inosamine-4-phosphate amidinotransferase 1 [EC:2.1.4.2]
K12255  guanidinobutyrase [EC:3.5.3.7]
K12676  proclavaminate amidinohydrolase [EC:3.5.3.22]
K19723  Nomega-hydroxy-L-arginine amidinohydrolase [EC:3.5.3.25]

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