KEGG   REACTION: R06265
Entry
R06265                      Reaction                               

Name
magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)
Definition
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
Equation
Comment
first step of three-step reaction (see R10068, R06265+R06266+R06267)
Reaction class
RC00001  C00005_C00006
RC00741  C04536_C11829
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K04035  magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:1.14.13.81]
Other DBs
RHEA: 24275

KEGG   RCLASS: RC00741
Entry
RC00741                     RClass                                 

Definition
C1b-C1c:*-O1a:C1b+C8y-C1b+C8y
Reactant pair
Related class
Reaction
Enzyme
1.14.13.81      1.14.15.37      1.14.17.1       1.21.98.3
Pathway
rn00350  Tyrosine metabolism
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00503  dopamine beta-monooxygenase [EC:1.14.17.1]
K04034  anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase [EC:1.21.98.3]
K04035  magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:1.14.13.81]

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