KEGG   REACTION: R06266
Entry
R06266                      Reaction                               

Name
magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)
Definition
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O
Equation
Comment
second step of three-step reaction (see R10068, R06265+R06266+R06267)
Reaction class
RC00001  C00005_C00006
RC01491  C11829_C11830
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K04035  magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:1.14.13.81]
Other DBs
RHEA: 20544

KEGG   RCLASS: RC01491
Entry
RC01491                     RClass                                 

Definition
C1c-C5a:*-*:C1b+C8y+O1a-C1b+C8y+O5a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.146       1.1.1.184       1.1.1.349       1.3.1.20        
1.14.13.81      1.21.98.3
Pathway
rn00254  Aflatoxin biosynthesis
rn00860  Porphyrin and chlorophyll metabolism
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00980  Metabolism of xenobiotics by cytochrome P450
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00079  carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00081  carbonyl reductase 2 [EC:1.1.1.184]
K00084  carbonyl reductase 3 [EC:1.1.1.184]
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K04034  anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase [EC:1.21.98.3]
K04035  magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:1.14.13.81]
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K17644  norsolorinic acid ketoreductase [EC:1.1.1.349]

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