KEGG   REACTION: R06291
Entry
R06291                      Reaction                               

Name
ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
ent-Kaurene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
the first step of three-step reaction (see R10066, R06291+R06292+R06293)
Reaction class
RC00257  C06090_C11872
Enzyme
Pathway
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00927  Gibberellin A12 biosynthesis, GAPP => GA12
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K21292  ent-kaurene oxidase [EC:1.14.14.86]
Other DBs
RHEA: 13048

KEGG   RCLASS: RC00257
Entry
RC00257                     RClass                                 

Definition
C1a-C1b:*-O1a:C1z-C1z
Reactant pair
Related class
Reaction
Enzyme
1.14.11.12      1.14.13.246     1.14.13.-       1.14.14.14      
1.14.14.67      1.14.14.86      1.14.14.111     1.14.14.115     
1.14.14.126     1.14.14.134     1.14.14.137     1.14.14.144     
1.14.14.154     1.14.15.4       1.14.15.5       1.14.15.36      
1.14.18.9       1.14.18.10
Pathway
rn00140  Steroid hormone biosynthesis
rn00904  Diterpenoid biosynthesis
rn00906  Carotenoid biosynthesis
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn00981  Insect hormone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K05282  gibberellin-44 dioxygenase [EC:1.14.11.12]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K07434  aromatase [EC:1.14.14.14]
K09843  (+)-abscisic acid 8'-hydroxylase [EC:1.14.14.137]
K12918  cytochrome P450 monooxygenase 2
K15814  beta-amyrin 24-hydroxylase [EC:1.14.14.134]
K15826  sesquiterpenoid omega-hydroxylase
K21292  ent-kaurene oxidase [EC:1.14.14.86]
K22637  11-hydroxysugiol 20-monooxygenase [EC:1.14.14.67]

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