KEGG   REACTION: R06294
Entry
R06294                      Reaction                               

Name
ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
Kaur-16-en-18-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
the first step of three-step reaction (see R10067, R06294+R06295+R06297)
Reaction class
RC01218  C11874_C11875
Enzyme
Pathway
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00927  Gibberellin A12 biosynthesis, GAPP => GA12
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Orthology
K04123  ent-kaurenoic acid monooxygenase [EC:1.14.14.107]
K12917  cytochrome P450 monooxygenase 1
Other DBs
RHEA: 19244

KEGG   RCLASS: RC01218
Entry
RC01218                     RClass                                 

Definition
C1x-C1y:*-O1a:C1x+C1z-C1x+C1z
Reactant pair
Related class
Reaction
Enzyme
1.14.11.15      1.14.13.147     1.14.13.161     1.14.13.-       
1.14.14.56      1.14.14.63      1.14.14.68      1.14.14.70      
1.14.14.71      1.14.14.107     1.14.14.133     1.14.14.139     
1.14.14.171     1.14.15.10      1.14.15.19
Pathway
rn00120  Primary bile acid biosynthesis
rn00403  Indole diterpene alkaloid biosynthesis
rn00902  Monoterpenoid biosynthesis
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K04123  ent-kaurenoic acid monooxygenase [EC:1.14.14.107]
K04124  gibberellin 3beta-dioxygenase [EC:1.14.11.15]
K07431  sterol 12-alpha-hydroxylase [EC:1.14.14.139]
K12917  cytochrome P450 monooxygenase 1
K18393  cytochrome P450 monooxygenase [EC:1.14.13.-]
K21120  1,8-cineole 2-endo-monooxygenase [EC:1.14.14.133]
K21719  ent-sandaracopimaradiene 3-hydroxylase / syn-pimaradiene 3-monooxygenase [EC:1.14.14.70 1.14.14.68]

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