KEGG   REACTION: R07079
Entry
R07079                      Reaction                               

Name
Benzpyrene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-9,10-oxide + NADP+ + H2O
Equation
Comment
CYP1A1, CYP1B1, CYP2C9, CYP3A4
Reaction class
RC00001  C00005_C00006
RC01445  C07535_C14849
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]

KEGG   REACTION: R07080
Entry
R07080                      Reaction                               

Name
Benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-oxide + NADP+ + H2O
Equation
Comment
CYP1A1, CYP1B1, CYP2C9, CYP3A4
Reaction class
RC00001  C00005_C00006
RC01445  C07535_C14850
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]

KEGG   REACTION: R07081
Entry
R07081                      Reaction                               

Name
benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-4,5-oxide + NADP+ + H2O
Equation
Comment
CYP1A1, CYP1B1, CYP2C9, CYP3A4
Reaction class
RC00001  C00005_C00006
RC01444  C07535_C14851
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]

KEGG   RCLASS: RC01445
Entry
RC01445                     RClass                                 

Definition
C1y-C8x:O2x-*:C1y+C2x-C8x+C8x
C1y-C8x:O2x-*:C1y+C8y-C8x+C8y
Reactant pair
Related class
Reaction
Enzyme
1.14.13.-       1.14.14.1       1.14.14.-       1.14.-.-
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn00980  Metabolism of xenobiotics by cytochrome P450
rn01120  Microbial metabolism in diverse environments
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07412  cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07416  cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07420  cytochrome P450 family 2 subfamily S1 [EC:1.14.14.1]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]

KEGG   RCLASS: RC01444
Entry
RC01444                     RClass                                 

Definition
C1y-C8x:O2x-*:C1y+C8y-C8x+C8y
C1y-C8x:O2x-*:C1y+C8y-C8x+C8y
Reactant pair
Related class
Reaction
Enzyme
1.14.13.-       1.14.14.1       1.14.14.-       1.14.-.-
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn00980  Metabolism of xenobiotics by cytochrome P450
rn01120  Microbial metabolism in diverse environments
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]

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