KEGG   REACTION: R07302
Entry
R07302                      Reaction                               

Name
adenosylcobyric acid:(R)-1-aminopropan-2-ol ligase (ADP-forming)
Definition
ATP + Adenosyl cobyrinate hexaamide + (R)-1-Aminopropan-2-ol <=> ADP + Orthophosphate + Adenosyl cobinamide
Equation
Reaction class
RC00002  C00002_C00008
RC00090  C06507_C06508
RC00096  C03194_C06508
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00122  Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin
Orthology
K02225  cobalamin biosynthesis protein CobC
K02227  adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
Other DBs
RHEA: 12575

KEGG   RCLASS: RC00090
Entry
RC00090                     RClass                                 

Definition
C5a-C6a:N1b+*-*+O6a:C1b+O5a-C1b+O6a
Reactant pair
C00025_C00051    C00025_C00669    C00025_C01047
C00025_C02166    C00025_C02320    C00025_C03153
C00025_C04138    C00025_C05711    C00025_C06114
C00025_C06462    C00025_C15699    C00025_C15767
C00025_C18008    C00025_C20843    C00025_C20926
C00025_C20995    C00025_C21015    C00025_C21539
C00025_C21620    C00025_C21622    C00025_C21664
C00025_C22139    C00025_C22140    C00026_C03623
C00026_C21858    C00037_C03838    C00042_C04421
C00042_C05931    C00049_C04540    C00051_C02090
 » show all
Related class
Reaction
Enzyme
2.3.1.164       2.3.2.2         2.3.2.-         3.1.1.1         
3.4.13.4        3.4.13.5        3.4.13.18       3.4.13.20       
3.4.14.13       3.4.19.9        3.4.19.13       3.4.19.14       
3.4.19.16       3.5.1.11        3.5.1.12        3.5.1.18        
3.5.1.24        3.5.1.26        3.5.1.36        3.5.1.39        
3.5.1.46        3.5.1.52        3.5.1.55        3.5.1.65        
3.5.1.74        3.5.1.78        3.5.1.90        3.5.1.92        
3.5.1.93        3.5.1.94        3.5.1.95        3.5.1.96        
3.5.1.99        3.5.1.118       3.5.1.119       3.5.1.127       
3.5.1.128       3.5.1.130       3.5.1.132       3.5.1.134       
3.5.1.-         3.13.1.6        6.2.1.39        6.3.1.6         
6.3.1.8         6.3.1.9         6.3.1.10        6.3.1.11        
6.3.1.18        6.3.1.19        6.3.1.20        6.3.2.2         
6.3.2.5         6.3.2.7         6.3.2.11        6.3.2.12        
6.3.2.13        6.3.2.17        6.3.2.18        6.3.2.20        
6.3.2.26        6.3.2.30        6.3.2.32        6.3.2.34        
6.3.2.37        6.3.2.38        6.3.2.39        6.3.2.43        
6.3.2.51        6.3.2.52        6.3.2.-         6.3.4.9         
6.3.4.10        6.3.4.11        6.3.4.12        6.3.4.13        
6.3.4.15        6.3.4.24
 » show all
Pathway
rn00120  Primary bile acid biosynthesis
rn00240  Pyrimidine metabolism
rn00311  Penicillin and cephalosporin biosynthesis
rn00330  Arginine and proline metabolism
rn00380  Tryptophan metabolism
rn00410  beta-Alanine metabolism
rn00480  Glutathione metabolism
rn00550  Peptidoglycan biosynthesis
rn00680  Methane metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00780  Biotin metabolism
rn00790  Folate biosynthesis
rn00860  Porphyrin and chlorophyll metabolism
rn00930  Caprolactam degradation
rn00997  Biosynthesis of various secondary metabolites - part 3
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K00681  gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K01307  gamma-glutamyl hydrolase [EC:3.4.19.9]
K01435  biotinidase [EC:3.5.1.12]
K01439  succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
K01442  choloylglycine hydrolase [EC:3.5.1.24]
K01453  6-aminohexanoate-oligomer exohydrolase [EC:3.5.1.46]
K01460  glutathionylspermidine amidase/synthetase [EC:3.5.1.78 6.3.1.8]
K01833  trypanothione synthetase/amidase [EC:6.3.1.9 3.5.1.-]
K01917  glutathionylspermidine synthase [EC:6.3.1.8]
K01919  glutamate--cysteine ligase [EC:6.3.2.2]
K01922  phosphopantothenate---cysteine ligase (ATP) [EC:6.3.2.51]
K01928  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K01945  phosphoribosylamine---glycine ligase [EC:6.3.4.13]
K02225  cobalamin biosynthesis protein CobC
K02227  adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
K03800  lipoate---protein ligase [EC:6.3.1.20]
K03894  N2-citryl-N6-acetyl-N6-hydroxylysine synthase [EC:6.3.2.38]
K03895  aerobactin synthase [EC:6.3.2.39]
K05362  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
K05526  succinylglutamate desuccinylase [EC:3.5.1.96]
K05604  beta-Ala-His dipeptidase [EC:3.4.13.20]
K05827  [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
K05831  [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
K06048  glutamate---cysteine ligase / carboxylate-amine ligase [EC:6.3.2.2 6.3.-.-]
K06914  tyramine---L-glutamate ligase [EC:6.3.4.24]
K07008  gamma-glutamyl hercynylcysteine S-oxide hydrolase [EC:3.5.1.118]
K08069  pantetheine hydrolase [EC:3.5.1.92]
K08260  adenosylcobinamide hydrolase [EC:3.5.1.90]
K08660  cytosolic nonspecific dipeptidase [EC:3.4.13.18]
K09470  gamma-glutamylputrescine synthase [EC:6.3.1.11]
K09473  gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
K10852  isopenicillin-N N-acyltransferase [EC:2.3.1.164]
K11204  glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205  glutamate--cysteine ligase regulatory subunit
K11206  deaminated glutathione amidase [EC:3.5.1.128]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K11788  phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
K12234  coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
K12743  N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase [EC:6.3.2.26]
K12748  glutaryl-7-aminocephalosporanic-acid acylase [EC:3.5.1.93]
K13038  phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
K13559  [BtrI acyl-carrier protein]--L-glutamate ligase [EC:6.2.1.39]
K13571  proteasome accessory factor A [EC:6.3.1.19]
K13713  fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
K14506  jasmonic acid-amino synthetase [EC:6.3.2.52]
K14755  carnosine synthase [EC:6.3.2.11]
K14940  gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32]
K15792  MurE/MurF fusion protein [EC:6.3.2.13 6.3.2.10]
K18572  putative pantetheine hydrolase [EC:3.5.1.-]
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K19412  glutamate--LysW ligase ArgX [EC:6.3.2.-]
K19795  ureidomalonase [EC:3.5.1.95]
K21140  [CysO sulfur-carrier protein]-S-L-cysteine hydrolase [EC:3.13.1.6]
K21604  jasmonoyl-L-amino acid hydrolase [EC:3.5.1.127]
K21977  phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K22314  glucosinolate gamma-glutamyl hydrolase [EC:3.4.19.16]
K23672  L-propargylglycine--L-glutamate ligase [EC:6.3.2.-]

KEGG   RCLASS: RC00096
Entry
RC00096                     RClass                                 

Definition
N1a-N1b:*-C5a:C1b-C1b
Reactant pair
C00037_C00051    C00037_C01419    C00037_C01586
C00037_C01921    C00037_C02055    C00037_C02564
C00037_C05380    C00037_C05464    C00037_C05466
C00037_C05596    C00037_C05598    C00037_C05729
C00037_C05951    C00037_C16623    C00037_C21016
C00047_C02427    C00047_C02444    C00047_C02727
C00047_C04211    C00047_C05552    C00047_C20278
C00047_C21730    C00077_C00327    C00099_C00864
C00099_C01073    C00099_C02642    C00099_C03492
C00099_C04544    C00134_C00436    C00134_C02714
 » show all
Related class
Reaction
R00059 R00395 R00454 R00458 R00497 R00545 R00665 R00899
R00905 R00909 R01077 R01152 R01154 R01156 R01396 R01398
R01399 R01424 R01425 R01617 R01620 R01687 R01723 R01889
R01917 R01918 R01944 R01987 R02041 R02152 R02276 R02385
R02452 R02473 R02474 R02741 R02797 R02911 R02929 R02930
R02973 R03095 R03552 R03579 R03718 R03720 R03760 R03822
R03910 R03956 R03971 R03975 R03977 R03992 R04056 R04174
R04192 R04211 R04252 R04486 R04487 R04562 R04563 R04582
R04604 R04613 R04666 R04777 R04951 R04975 R05055 R05145
R05226 R05835 R05841 R06529 R06978 R07245 R07300 R07301
 » show all
Enzyme
2.1.3.3         2.1.3.6         2.1.3.8         2.1.3.9         
2.1.3.11        2.3.1.13        2.3.1.32        2.3.1.48        
2.3.1.57        2.3.1.58        2.3.1.64        2.3.1.65        
2.3.1.71        2.3.1.82        2.3.1.87        2.3.1.97        
2.3.1.108       2.3.1.110       2.3.1.138       2.3.1.178       
2.3.1.192       2.3.1.264       2.3.1.280       2.3.1.286       
2.3.1.-         2.3.2.2         2.3.2.10        2.3.2.15        
2.3.2.16        2.3.2.17        2.3.2.18        2.3.2.35        
2.3.2.-         3.4.11.1        3.4.11.2        3.4.11.23       
3.4.13.23       3.4.13.-        3.5.1.6         3.5.1.12        
3.5.1.17        3.5.1.20        3.5.1.21        3.5.1.22        
3.5.1.24        3.5.1.32        3.5.1.40        3.5.1.46        
3.5.1.48        3.5.1.51        3.5.1.53        3.5.1.60        
3.5.1.62        3.5.1.63        3.5.1.65        3.5.1.71        
3.5.1.74        3.5.1.78        3.5.1.85        3.5.1.90        
3.5.1.92        3.5.1.94        3.5.1.99        3.5.1.119       
3.5.1.-         4.3.2.6         4.3.2.8         6.2.1.39        
6.3.1.6         6.3.1.8         6.3.1.9         6.3.1.10        
6.3.1.11        6.3.1.19        6.3.2.1         6.3.2.3         
6.3.2.18        6.3.2.20        6.3.2.23        6.3.2.36        
6.3.2.37        6.3.2.44        6.3.2.46        6.3.2.-         
6.3.4.9         6.3.4.10        6.3.4.11        6.3.4.15        
6.3.4.24
 » show all
Pathway
rn00120  Primary bile acid biosynthesis
rn00220  Arginine biosynthesis
rn00240  Pyrimidine metabolism
rn00260  Glycine, serine and threonine metabolism
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn00330  Arginine and proline metabolism
rn00332  Carbapenem biosynthesis
rn00340  Histidine metabolism
rn00380  Tryptophan metabolism
rn00410  beta-Alanine metabolism
rn00430  Taurine and hypotaurine metabolism
rn00440  Phosphonate and phosphinate metabolism
rn00460  Cyanoamino acid metabolism
rn00480  Glutathione metabolism
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00550  Peptidoglycan biosynthesis
rn00680  Methane metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00780  Biotin metabolism
rn00860  Porphyrin and chlorophyll metabolism
rn00930  Caprolactam degradation
rn00983  Drug metabolism - other enzymes
rn00997  Biosynthesis of various secondary metabolites - part 3
rn00998  Biosynthesis of various secondary metabolites - part 2
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
RModule
RM024  Pyrimidine degradation
Orthology
K00611  ornithine carbamoyltransferase [EC:2.1.3.3]
K00628  glycine N-acyltransferase / glycine N-benzoyltransferase [EC:2.3.1.13 2.3.1.71]
K00657  diamine N-acetyltransferase [EC:2.3.1.57]
K00659  bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K00669  arylalkylamine N-acetyltransferase [EC:2.3.1.87]
K00681  gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K01255  leucyl aminopeptidase [EC:3.4.11.1]
K01256  aminopeptidase N [EC:3.4.11.2]
K01270  dipeptidase D [EC:3.4.13.-]
K01431  beta-ureidopropionase [EC:3.5.1.6]
K01435  biotinidase [EC:3.5.1.12]
K01442  choloylglycine hydrolase [EC:3.5.1.24]
K01451  hippurate hydrolase [EC:3.5.1.32]
K01453  6-aminohexanoate-oligomer exohydrolase [EC:3.5.1.46]
K01460  glutathionylspermidine amidase/synthetase [EC:3.5.1.78 6.3.1.8]
K01833  trypanothione synthetase/amidase [EC:6.3.1.9 3.5.1.-]
K01917  glutathionylspermidine synthase [EC:6.3.1.8]
K01918  pantoate--beta-alanine ligase [EC:6.3.2.1]
K01920  glutathione synthase [EC:6.3.2.3]
K01942  biotin---protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]
K01947  biotin---[acetyl-CoA-carboxylase] ligase / type III pantothenate kinase [EC:6.3.4.15 2.7.1.33]
K02225  cobalamin biosynthesis protein CobC
K02227  adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
K03524  BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
K05363  serine/alanine adding enzyme [EC:2.3.2.10]
K06016  beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
K06718  L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178]
K06914  tyramine---L-glutamate ligase [EC:6.3.4.24]
K07751  PepB aminopeptidase [EC:3.4.11.23]
K08069  pantetheine hydrolase [EC:3.5.1.92]
K08260  adenosylcobinamide hydrolase [EC:3.5.1.90]
K09065  N-acetylornithine carbamoyltransferase [EC:2.1.3.9]
K09470  gamma-glutamylputrescine synthase [EC:6.3.1.11]
K09473  gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
K09722  4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
K09994  (aminoalkyl)phosphonate N-acetyltransferase [EC:2.3.1.280]
K11121  NAD+-dependent protein deacetylase SIR2 [EC:2.3.1.286]
K11140  aminopeptidase N [EC:3.4.11.2]
K11142  cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11411  NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11412  NAD+-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
K11413  NAD+-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K11414  NAD+-dependent protein deacetylase sirtuin 4 [EC:2.3.1.286]
K11415  NAD+-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
K11416  NAD+-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K11417  NAD+-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286]
K11693  peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16]
K11694  peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17]
K11695  peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18]
K12251  N-carbamoylputrescine amidase [EC:3.5.1.53]
K12410  NAD-dependent deacetylase [EC:2.3.1.286]
K13043  N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11]
K13559  [BtrI acyl-carrier protein]--L-glutamate ligase [EC:6.2.1.39]
K13564  gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase [EC:4.3.2.6]
K13571  proteasome accessory factor A [EC:6.3.1.19]
K13799  pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25]
K14329  agmatine coumaroyltransferase [EC:2.3.1.64 2.3.1.-]
K15428  Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
K15517  glycine N-phenylacetyltransferase [EC:2.3.1.192]
K16181  3-methylornithine--L-lysine ligase [EC:6.3.2.-]
K18566  N-acetyltransferase [EC:2.3.1.-]
K18572  putative pantetheine hydrolase [EC:3.5.1.-]
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18854  lysine N-acetyltransferase [EC:2.3.1.32]
K21456  glutathione synthase [EC:6.3.2.3]
K21935  beta-lysine N6-acetyltransferase [EC:2.3.1.264]
K22113  fumarate---(S)-2,3-diaminopropanoate ligase [EC:6.3.2.46]
K22450  aralkylamine N-acetyltransferase [EC:2.3.1.87]
K24277  capsaicin synthase [EC:2.3.2.35]

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