KEGG   REACTION: R08332
Entry
R08332                      Reaction                               
Name
acetyl-CoA:2-oxopimelate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Definition
2-Oxopimelate + Acetyl-CoA + H2O <=> (R)-(Homo)3-citrate + CoA
Equation
C16588 + C00024 + C00001 <=> C16598 + C00010
Reaction class
RC00004  C00010_C00024
RC00067  C16588_C16598
Enzyme
2.3.3.-
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01240  Biosynthesis of cofactors
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.-
     R08332  2-Oxopimelate + Acetyl-CoA + H2O <=> (R)-(Homo)3-citrate + CoA
Orthology
K10977  methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
Reference
1  [PMID:10940051]
  Authors
Howell DM, Graupner M, Xu H, White RH
  Title
Identification of enzymes homologous to isocitrate dehydrogenase that are involved in coenzyme B and leucine biosynthesis in methanoarchaea.
  Journal
J Bacteriol 182:5013-6 (2000)
DOI:10.1128/JB.182.17.5013-5016.2000
Other DBs
RHEA: 44931

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
Gene (127)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (126)   
All databases (146)   

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