KEGG   REACTION: R08648
Entry
R08648                      Reaction                               
Name
pyruvate:2-oxobutanoate acetaldehydetransferase (decarboxylating)
Definition
Pyruvate + 2-Oxobutanoate <=> (S)-2-Aceto-2-hydroxybutanoate + CO2
Equation
C00022 + C00109 <=> C06006 + C00011
Comment
TPP-dependent enzymatic reaction (R00014+R04673)
Reaction class
RC01192  C00109_C06006
Enzyme
2.2.1.6
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.6
     R08648  Pyruvate + 2-Oxobutanoate <=> (S)-2-Aceto-2-hydroxybutanoate + CO2
Orthology
K01652  acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  acetolactate synthase I/III small subunit [EC:2.2.1.6]
K11258  acetolactate synthase II small subunit [EC:2.2.1.6]
Other DBs
RHEA: 27657

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (12)   
   KEGG PATHWAY (10)   
   KEGG MODULE (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
   SABIO-RK (1)   
Gene (26748)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (26745)   
All databases (26768)   

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