KEGG   REACTION: R10011
Entry
R10011                      Reaction                               

Definition
L-Lysine + (2R,3R)-3-Methylornithine + ATP <=> (2R,3R)-3-Methylornithinyl-N6-lysine + Products of ATP breakdown
Equation
Comment
3-methylornithine--L-lysine ligase
Reaction class
RC00096  C00047_C20278
RC00141  C20277_C20278
Enzyme
6.3.2.-
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K16181  3-methylornithine--L-lysine ligase [EC:6.3.2.-]

KEGG   RCLASS: RC00096
Entry
RC00096                     RClass                                 

Definition
N1a-N1b:*-C5a:C1b-C1b
Reactant pair
C00037_C00051    C00037_C01419    C00037_C01586
C00037_C01921    C00037_C02055    C00037_C02564
C00037_C05380    C00037_C05464    C00037_C05466
C00037_C05596    C00037_C05598    C00037_C05729
C00037_C05951    C00037_C16623    C00037_C21016
C00047_C02427    C00047_C02444    C00047_C02727
C00047_C04211    C00047_C05552    C00047_C20278
C00047_C21730    C00077_C00327    C00099_C00864
C00099_C01073    C00099_C02642    C00099_C03492
C00099_C04544    C00134_C00436    C00134_C02714
 » show all
Related class
Reaction
R00059 R00395 R00454 R00458 R00497 R00545 R00665 R00899
R00905 R00909 R01077 R01152 R01154 R01156 R01396 R01398
R01399 R01424 R01425 R01617 R01620 R01687 R01723 R01889
R01917 R01918 R01944 R01987 R02041 R02152 R02276 R02385
R02452 R02473 R02474 R02741 R02797 R02911 R02929 R02930
R02973 R03095 R03552 R03579 R03718 R03720 R03760 R03822
R03910 R03956 R03971 R03975 R03977 R03992 R04056 R04174
R04192 R04211 R04252 R04486 R04487 R04562 R04563 R04582
R04604 R04613 R04666 R04777 R04951 R04975 R05055 R05145
R05226 R05835 R05841 R06529 R06978 R07245 R07300 R07301
 » show all
Enzyme
2.1.3.3         2.1.3.6         2.1.3.8         2.1.3.9         
2.1.3.11        2.3.1.13        2.3.1.32        2.3.1.48        
2.3.1.57        2.3.1.58        2.3.1.64        2.3.1.65        
2.3.1.71        2.3.1.82        2.3.1.87        2.3.1.97        
2.3.1.108       2.3.1.110       2.3.1.138       2.3.1.178       
2.3.1.192       2.3.1.264       2.3.1.280       2.3.1.286       
2.3.1.-         2.3.2.2         2.3.2.10        2.3.2.15        
2.3.2.16        2.3.2.17        2.3.2.18        2.3.2.35        
2.3.2.-         3.4.11.1        3.4.11.2        3.4.11.23       
3.4.13.23       3.4.13.-        3.5.1.6         3.5.1.12        
3.5.1.17        3.5.1.20        3.5.1.21        3.5.1.22        
3.5.1.24        3.5.1.32        3.5.1.40        3.5.1.46        
3.5.1.48        3.5.1.51        3.5.1.53        3.5.1.60        
3.5.1.62        3.5.1.63        3.5.1.65        3.5.1.71        
3.5.1.74        3.5.1.78        3.5.1.85        3.5.1.90        
3.5.1.92        3.5.1.94        3.5.1.99        3.5.1.119       
3.5.1.-         4.3.2.6         4.3.2.8         6.2.1.39        
6.3.1.6         6.3.1.8         6.3.1.9         6.3.1.10        
6.3.1.11        6.3.1.19        6.3.2.1         6.3.2.3         
6.3.2.18        6.3.2.20        6.3.2.23        6.3.2.36        
6.3.2.37        6.3.2.44        6.3.2.46        6.3.2.-         
6.3.4.9         6.3.4.10        6.3.4.11        6.3.4.15        
6.3.4.24
 » show all
Pathway
rn00120  Primary bile acid biosynthesis
rn00220  Arginine biosynthesis
rn00240  Pyrimidine metabolism
rn00260  Glycine, serine and threonine metabolism
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn00330  Arginine and proline metabolism
rn00332  Carbapenem biosynthesis
rn00340  Histidine metabolism
rn00380  Tryptophan metabolism
rn00410  beta-Alanine metabolism
rn00430  Taurine and hypotaurine metabolism
rn00440  Phosphonate and phosphinate metabolism
rn00460  Cyanoamino acid metabolism
rn00480  Glutathione metabolism
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00550  Peptidoglycan biosynthesis
rn00680  Methane metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00780  Biotin metabolism
rn00860  Porphyrin and chlorophyll metabolism
rn00930  Caprolactam degradation
rn00983  Drug metabolism - other enzymes
rn00997  Biosynthesis of various secondary metabolites - part 3
rn00998  Biosynthesis of various secondary metabolites - part 2
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
RModule
RM024  Pyrimidine degradation
Orthology
K00611  ornithine carbamoyltransferase [EC:2.1.3.3]
K00628  glycine N-acyltransferase / glycine N-benzoyltransferase [EC:2.3.1.13 2.3.1.71]
K00657  diamine N-acetyltransferase [EC:2.3.1.57]
K00659  bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K00669  arylalkylamine N-acetyltransferase [EC:2.3.1.87]
K00681  gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K01255  leucyl aminopeptidase [EC:3.4.11.1]
K01256  aminopeptidase N [EC:3.4.11.2]
K01270  dipeptidase D [EC:3.4.13.-]
K01431  beta-ureidopropionase [EC:3.5.1.6]
K01435  biotinidase [EC:3.5.1.12]
K01442  choloylglycine hydrolase [EC:3.5.1.24]
K01451  hippurate hydrolase [EC:3.5.1.32]
K01453  6-aminohexanoate-oligomer exohydrolase [EC:3.5.1.46]
K01460  glutathionylspermidine amidase/synthetase [EC:3.5.1.78 6.3.1.8]
K01833  trypanothione synthetase/amidase [EC:6.3.1.9 3.5.1.-]
K01917  glutathionylspermidine synthase [EC:6.3.1.8]
K01918  pantoate--beta-alanine ligase [EC:6.3.2.1]
K01920  glutathione synthase [EC:6.3.2.3]
K01942  biotin---protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]
K01947  biotin---[acetyl-CoA-carboxylase] ligase / type III pantothenate kinase [EC:6.3.4.15 2.7.1.33]
K02225  cobalamin biosynthesis protein CobC
K02227  adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
K03524  BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
K05363  serine/alanine adding enzyme [EC:2.3.2.10]
K06016  beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
K06718  L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178]
K06914  tyramine---L-glutamate ligase [EC:6.3.4.24]
K07751  PepB aminopeptidase [EC:3.4.11.23]
K08069  pantetheine hydrolase [EC:3.5.1.92]
K08260  adenosylcobinamide hydrolase [EC:3.5.1.90]
K09065  N-acetylornithine carbamoyltransferase [EC:2.1.3.9]
K09470  gamma-glutamylputrescine synthase [EC:6.3.1.11]
K09473  gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
K09722  4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
K09994  (aminoalkyl)phosphonate N-acetyltransferase [EC:2.3.1.280]
K11121  NAD+-dependent protein deacetylase SIR2 [EC:2.3.1.286]
K11140  aminopeptidase N [EC:3.4.11.2]
K11142  cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11411  NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11412  NAD+-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
K11413  NAD+-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K11414  NAD+-dependent protein deacetylase sirtuin 4 [EC:2.3.1.286]
K11415  NAD+-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
K11416  NAD+-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K11417  NAD+-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286]
K11693  peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16]
K11694  peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17]
K11695  peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18]
K12251  N-carbamoylputrescine amidase [EC:3.5.1.53]
K12410  NAD-dependent deacetylase [EC:2.3.1.286]
K13043  N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11]
K13559  [BtrI acyl-carrier protein]--L-glutamate ligase [EC:6.2.1.39]
K13564  gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase [EC:4.3.2.6]
K13571  proteasome accessory factor A [EC:6.3.1.19]
K13799  pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25]
K14329  agmatine coumaroyltransferase [EC:2.3.1.64 2.3.1.-]
K15428  Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
K15517  glycine N-phenylacetyltransferase [EC:2.3.1.192]
K16181  3-methylornithine--L-lysine ligase [EC:6.3.2.-]
K18566  N-acetyltransferase [EC:2.3.1.-]
K18572  putative pantetheine hydrolase [EC:3.5.1.-]
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18854  lysine N-acetyltransferase [EC:2.3.1.32]
K21456  glutathione synthase [EC:6.3.2.3]
K21935  beta-lysine N6-acetyltransferase [EC:2.3.1.264]
K22113  fumarate---(S)-2,3-diaminopropanoate ligase [EC:6.3.2.46]
K22450  aralkylamine N-acetyltransferase [EC:2.3.1.87]
K24277  capsaicin synthase [EC:2.3.2.35]

KEGG   RCLASS: RC00141
Entry
RC00141                     RClass                                 

Definition
C5a-C6a:N1b+*-*+O6a:C1c+O5a-C1c+O6a
Reactant pair
C00041_C20942    C00051_C00669    C00062_C21099
C00082_C02993    C00082_C07027    C00097_C01419
C00097_C19703    C00133_C00993    C00133_C04457
C00133_C19719    C00151_C16116    C00522_C00864
C00669_C04544    C00692_C01212    C01042_C12270
C01042_C20776    C01050_C01212    C01050_C04877
C01217_C18802    C01392_C05234    C02170_C20846
C02713_C02999    C02882_C05729    C03001_C04303
C03492_C18911    C04506_C20120    C04650_C06457
C04702_C05892    C04702_C06432    C04804_C04882
 » show all
Related class
Reaction
Enzyme
2.3.2.-         3.4.11.1        3.4.11.2        3.4.11.23       
3.4.13.22       3.4.13.23       3.4.13.-        3.4.15.6        
3.4.17.8        3.4.17.21       3.4.22.-        3.4.24.84       
3.4.-.-         3.5.1.22        3.5.1.28        3.5.1.72        
3.5.1.95        3.5.1.115       6.3.1.13        6.3.2.1         
6.3.2.3         6.3.2.4         6.3.2.8         6.3.2.9         
6.3.2.10        6.3.2.16        6.3.2.23        6.3.2.24        
6.3.2.25        6.3.2.29        6.3.2.31        6.3.2.33        
6.3.2.35        6.3.2.36        6.3.2.41        6.3.2.42        
6.3.2.44        6.3.2.45        6.3.2.48        6.3.2.49        
6.3.2.-
 » show all
Pathway
rn00240  Pyrimidine metabolism
rn00250  Alanine, aspartate and glutamate metabolism
rn00261  Monobactam biosynthesis
rn00270  Cysteine and methionine metabolism
rn00300  Lysine biosynthesis
rn00440  Phosphonate and phosphinate metabolism
rn00471  D-Glutamine and D-glutamate metabolism
rn00473  D-Alanine metabolism
rn00480  Glutathione metabolism
rn00550  Peptidoglycan biosynthesis
rn00590  Arachidonic acid metabolism
rn00680  Methane metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00790  Folate biosynthesis
rn00900  Terpenoid backbone biosynthesis
rn00998  Biosynthesis of various secondary metabolites - part 2
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01255  leucyl aminopeptidase [EC:3.4.11.1]
K01256  aminopeptidase N [EC:3.4.11.2]
K01270  dipeptidase D [EC:3.4.13.-]
K01446  peptidoglycan recognition protein
K01447  N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K01448  N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K01449  N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K01798  Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]
K01918  pantoate--beta-alanine ligase [EC:6.3.2.1]
K01920  glutathione synthase [EC:6.3.2.3]
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
K01924  UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
K01925  UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
K05375  MbtH protein
K06013  STE24 endopeptidase [EC:3.4.24.84]
K07751  PepB aminopeptidase [EC:3.4.11.23]
K08658  prenyl protein peptidase [EC:3.4.22.-]
K09722  4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
K11140  aminopeptidase N [EC:3.4.11.2]
K11142  cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K12234  coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
K12631  puromycin biosynthesis protein Pur6
K12911  peptide synthetase PhsA
K12912  peptide synthetase PhsB
K12913  peptide synthetase PhsC
K13037  L-alanine-L-anticapsin ligase [EC:6.3.2.49]
K13282  cyanophycinase [EC:3.4.15.6]
K13799  pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25]
K14592  glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21]
K15428  Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
K15740  tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33]
K15792  MurE/MurF fusion protein [EC:6.3.2.13 6.3.2.10]
K16181  3-methylornithine--L-lysine ligase [EC:6.3.2.-]
K18310  beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41]
K18311  N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42]
K19102  nocardicin nonribosomal peptide synthetase NocA
K19103  nocardicin nonribosomal peptide synthetase NocB
K19111  putative tabtoxin peptidase [EC:3.4.-.-]
K19112  L-Amino acid ligase [EC:6.3.2.-]
K19795  ureidomalonase [EC:3.5.1.95]
K21456  glutathione synthase [EC:6.3.2.3]

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