KEGG   REACTION: R10393
Entry
R10393                      Reaction                               

Name
(-)-threo-iso(homo)2-citrate hydro-lyase
Definition
cis-(Homo)2-aconitate + H2O <=> (-)-threo-Iso(homo)2-citrate
Equation
Comment
second step of two-step reaction (see R10391, R10392+R10393)
Reaction class
RC00618  C16597_C20581
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Orthology
K16792  methanogen homoaconitase large subunit [EC:4.2.1.114]
K16793  methanogen homoaconitase small subunit [EC:4.2.1.114]

KEGG   RCLASS: RC00618
Entry
RC00618                     RClass                                 

Definition
C1c-C2b:O1a-*:C1c+C6a-C2c+C6a
C1c-C2c:*-*:C1b+C1c+C6a-C1b+C2b+C6a
Reactant pair
Related class
Reaction
Enzyme
4.2.1.3         4.2.1.36        4.2.1.114
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00300  Lysine biosynthesis
rn00630  Glyoxylate and dicarboxylate metabolism
rn00680  Methane metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01681  aconitate hydratase [EC:4.2.1.3]
K01682  aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
K01705  homoaconitate hydratase [EC:4.2.1.36]
K16792  methanogen homoaconitase large subunit [EC:4.2.1.114]
K16793  methanogen homoaconitase small subunit [EC:4.2.1.114]

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