KEGG   REACTION: R11197
Entry
R11197                      Reaction                               

Definition
4-Hydroxyisophthalate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NAD+ + CO2
Equation
Comment
4-hydroxyisophthalate hydroxylase
NADPH (see R11198)
Reaction class
RC00389  C00230_C21168
Enzyme
1.14.13.-
Pathway
rn00623  Toluene degradation
rn01120  Microbial metabolism in diverse environments
Orthology
K20218  4-hydroxyisophthalate hydroxylase

KEGG   REACTION: R11198
Entry
R11198                      Reaction                               

Definition
4-Hydroxyisophthalate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NADP+ + CO2
Equation
Comment
4-hydroxyisophthalate hydroxylase
NADH (see R11197)
Reaction class
RC00389  C00230_C21168
Enzyme
1.14.13.-
Pathway
rn00623  Toluene degradation
rn01120  Microbial metabolism in diverse environments
Orthology
K20218  4-hydroxyisophthalate hydroxylase

KEGG   RCLASS: RC00389
Entry
RC00389                     RClass                                 

Definition
C8y-C8y:C6a+*-*+O1a:C8x+C8y-C8x+C8y
Reactant pair
Related class
Reaction
Enzyme
1.14.13.1       1.14.13.135     1.14.13.218     1.14.13.-
Pathway
rn00405  Phenazine biosynthesis
rn00621  Dioxin degradation
rn00623  Toluene degradation
rn00624  Polycyclic aromatic hydrocarbon degradation
rn00626  Naphthalene degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM014  Ring removal from polycyclic aromatic ring
Orthology
K00480  salicylate hydroxylase [EC:1.14.13.1]
K20218  4-hydroxyisophthalate hydroxylase
K20940  5-methylphenazine-1-carboxylate 1-monooxygenase [EC:1.14.13.218]

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