KEGG   REACTION: R11283
Entry
R11283                      Reaction                               

Name
2'''-N-acetyl-6'''-deamino-6'''-hydroxyparomomycin-II hydrolase (acetate-forming)
Definition
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II + H2O <=> 6'''-Deamino-6'''-hydroxyparomomycin II + Acetate
Equation
Comment
deduced reaction
Reaction class
RC00166  C21261_C21262
RC00300  C00033_C21261
Enzyme
3.5.1.-
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K20583  deacetylase [EC:3.5.1.-]
Reference
1  [PMID:21689223]
  Authors
Clausnitzer D, Piepersberg W, Wehmeier UF
  Title
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
  Journal
J Appl Microbiol 111:642-51 (2011)
DOI:10.1111/j.1365-2672.2011.05082.x

KEGG   RCLASS: RC00166
Entry
RC00166                     RClass                                 

Definition
N1a-N1b:*-C5a:C1y-C1y
Reactant pair
Related class
Reaction
Enzyme
2.3.1.3         2.3.1.4         2.3.1.59        2.3.1.60        
2.3.1.78        2.3.1.81        2.3.1.157       2.3.1.191       
2.3.1.197       2.3.1.201       2.3.1.202       2.3.1.203       
2.3.1.209       2.3.1.210       2.3.1.227       2.3.1.-         
2.3.2.19        3.5.1.11        3.5.1.25        3.5.1.26        
3.5.1.33        3.5.1.41        3.5.1.52        3.5.1.89        
3.5.1.93        3.5.1.97        3.5.1.103       3.5.1.104       
3.5.1.105       3.5.1.108       3.5.1.112       3.5.1.113       
3.5.1.115       3.5.1.-         6.3.1.13        6.3.4.13
Pathway
rn00052  Galactose metabolism
rn00230  Purine metabolism
rn00311  Penicillin and cephalosporin biosynthesis
rn00520  Amino sugar and nucleotide sugar metabolism
rn00523  Polyketide sugar unit biosynthesis
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00540  Lipopolysaccharide biosynthesis
rn00541  O-Antigen nucleotide sugar biosynthesis
rn00950  Isoquinoline alkaloid biosynthesis
rn00998  Biosynthesis of various secondary metabolites - part 2
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00621  glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4]
K01434  penicillin G amidase [EC:3.5.1.11]
K01443  N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
K01452  chitin deacetylase [EC:3.5.1.41]
K01945  phosphoribosylamine---glycine ligase [EC:6.3.4.13]
K02079  N-acetylgalactosamine-6-phosphate deacetylase [EC:3.5.1.25]
K02535  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
K02536  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
K04042  bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K11788  phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
K12631  puromycin biosynthesis protein Pur6
K12748  glutaryl-7-aminocephalosporanic-acid acylase [EC:3.5.1.93]
K13018  UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase [EC:2.3.1.201]
K13551  2'-N-acetylparomamine deacetylase [EC:3.5.1.112]
K13563  ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase [EC:2.3.2.19]
K13713  fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
K15896  UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase [EC:2.3.1.202]
K15913  UDP-N-acetylbacillosamine N-acetyltransferase [EC:2.3.1.203]
K16363  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
K16704  dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase [EC:2.3.1.210]
K17078  2'-N-acetylparomamine deacetylase / 2'''-acetyl-6'''-hydroxyneomycin deacetylase [EC:3.5.1.112 3.5.1.113]
K17939  GDP-perosamine N-acetyltransferase [EC:2.3.1.227]
K20583  deacetylase [EC:3.5.1.-]
K20681  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197]
K21379  dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase [EC:2.3.1.209]
K24041  penicillin V amidase [EC:3.5.1.11]
K24251  dTDP-D-Quip3N acetylase [EC:2.3.1.-]
K24281  UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine acetyltransferase [EC:2.3.1.-]
K24303  UDP-N-acetylbacillosamine alanyltransferase

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