KEGG   REACTION: R11288
Entry
R11288                      Reaction                               

Name
5'''-epi-lividomycin-B 5'''-epimerase
Definition
5'''-epi-Lividomycin B <=> Lividomycin B
Equation
Comment
deduced reaction
Reaction class
RC01780  C18003_C21264
Enzyme
5.1.3.-
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K20588  5'''-epimerase [EC:5.1.3.-]
Reference
1  [PMID:21689223]
  Authors
Clausnitzer D, Piepersberg W, Wehmeier UF
  Title
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
  Journal
J Appl Microbiol 111:642-51 (2011)
DOI:10.1111/j.1365-2672.2011.05082.x

KEGG   RCLASS: RC01780
Entry
RC01780                     RClass                                 

Definition
C1y-C1y:*-*:C1b+C1y+O2x-C1b+C1y+O2x
Reactant pair
Related class
Reaction
Enzyme
5.1.3.18        5.1.3.-
Pathway
rn00053  Ascorbate and aldarate metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K10046  GDP-D-mannose 3', 5'-epimerase [EC:5.1.3.18 5.1.3.-]
K13557  neomycin C epimerase [EC:5.1.3.-]
K20588  5'''-epimerase [EC:5.1.3.-]

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