KEGG   Aggregatibacter aphrophilus W10433: ADJ80_05525
Entry
ADJ80_05525       CDS       T04521                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
aaz  Aggregatibacter aphrophilus W10433
Pathway
aaz00300  Lysine biosynthesis
aaz00550  Peptidoglycan biosynthesis
aaz01100  Metabolic pathways
aaz01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:aaz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    ADJ80_05525 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    ADJ80_05525 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    ADJ80_05525 (murF)
Enzymes [BR:aaz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     ADJ80_05525 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AKU63253
UniProt: A0A3M6P5P3
Position
1123280..1124659
AA seq 459 aa
MITLSLSQLASILDAQLLGDGALTVENVSTDSRQSISKGLFFALKGEHFDAHHYLDKAAE
QGCIAAVVERQTNASIAQLVVKDTRLALGQLAKWLREKINPKTVAMTGSSGKTTVKEMTA
AILQQSAVDFDDVLFTHGNFNNDIGVPLTLLRLTQQHKFAVIELGANHIGEIAYTTALAQ
PDVALVNNVAAAHLEGFGSLDGVATAKGEIYRGLTSNGTAIINLAHNYQQKWQAEIGDHS
VQYFAYDNPQADYYAENIVFSEQGASFLLHTPKGSIQIHSSYLGEHNVSNALAATALAMN
VGASLQDVQNGLAMKSQVKGRLFPIEPCENLLLLDDTYNANVGSMKSAISVLQKYPAFRV
FVVGDMAELGDNTQLCHQEVADFAHAAKLDLVLSCGHASEVISAVNSGKHFTDKTELANY
LISVIKQQVTEQKVVVLVKGSRSMKMENVIDLLKDSFLC
NT seq 1380 nt   +upstreamnt  +downstreamnt
atgattacattatctctttctcaacttgcttctattttagatgctcaattacttggcgac
ggcgcactgacggtagaaaacgtcagcactgacagccgccaatccatctcgaaaggttta
ttctttgccttaaaaggcgaacattttgatgcccatcattatttagataaagctgctgaa
caaggttgtattgccgccgtagtggaacgccaaacaaacgcttcgatcgcgcagttagtg
gtaaaagacacccgcttggcgctcggacaactggctaaatggttacgcgaaaagattaat
ccgaaaactgttgctatgacaggctcttccggcaagaccactgtaaaagaaatgacagcc
gccattttgcagcaaagtgcggtggattttgacgatgttttatttacccacggcaacttc
aacaatgacatcggcgtgccgctcacattattacgcttaacacaacaacataaatttgct
gtcattgaacttggcgcgaatcatatcggtgaaattgcttataccaccgccttggcgcaa
cctgatgtcgcgttggtgaataacgtggcggcggcacatttggaaggatttggttctctt
gatggcgtagcaaccgccaaaggcgaaatttaccgtggactaacctcaaacggcactgca
attattaatctcgcccataattatcaacaaaaatggcaggcggaaatcggtgaccattcg
gtgcaatattttgcttacgataatccgcaagccgattattatgctgaaaacattgtattt
tctgagcagggtgcttcttttcttttacatacgccaaaaggcagtattcaaattcattct
tcttatttgggtgaacataatgtcagcaatgccttggcggcaactgcattggcaatgaat
gtcggtgcgagtttgcaggatgtacaaaacggcttggcgatgaaatcccaagtgaaaggg
cgcttgttcccaattgagccttgtgaaaatctcttactcttggatgatacctacaacgct
aacgtaggttccatgaaatccgctatttccgtgttgcaaaaatatccggcatttcgcgtc
tttgttgttggtgatatggcggaattgggcgataatacacagctttgtcaccaagaggtg
gccgattttgcgcacgccgccaaattagatttggtgctttcttgtggccatgcgtcggaa
gtgataagtgcggtcaattcgggcaaacattttacggataaaactgagttggcaaattat
ttaatctccgtaattaaacaacaagtaacagaacaaaaagtcgttgttttggtgaaagga
tcacgcagtatgaaaatggaaaacgtgatcgatttattgaaggatagtttcctatgttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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