KEGG   Acanthamoeba castellanii: ACA1_192030
Entry
ACA1_192030       CDS       T02667                                 
Name
(RefSeq) ubiquitinactivating enzyme E1 1, putative
  KO
K03178  ubiquitin-activating enzyme E1 [EC:6.2.1.45]
Organism
acan  Acanthamoeba castellanii
Pathway
acan04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:acan00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    ACA1_192030
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:acan04121]
    ACA1_192030
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:acan04147]
    ACA1_192030
Enzymes [BR:acan01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.45  E1 ubiquitin-activating enzyme
     ACA1_192030
Ubiquitin system [BR:acan04121]
 Ubiquitin-activating enzymes (E1)
  Ubiquitin activating enzyme
   ACA1_192030
Exosome [BR:acan04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   ACA1_192030
  Exosomal proteins of other body fluids (saliva and urine)
   ACA1_192030
  Exosomal proteins of colorectal cancer cells
   ACA1_192030
SSDB
Motif
Pfam: UBA_E1_SCCH ThiF E1_UFD E1_FCCH E1_4HB
Other DBs
NCBI-GeneID: 14915087
NCBI-ProteinID: XP_004336486
UniProt: L8GPA4
Position
Unknown
AA seq 1049 aa
MEVEQTSTIERPTTNIDEGLYSRQLYVLNHADMLKITATDVLIVGLKGLGVEIAKNLVLA
GVRALLPPWPCYRCSLADPHPQNVGHCFLRESDVGRARAEACVDRLAELNSYVSVSLLSR
PLNAQTVSSFSVVVVTEAGWGQKLEVGEWCHERGVAFVGAEARGVFGSVFCDFGEAHTVL
DPNGEPPFQQMIASVTRDKPGVVTILDDRRLQLETGDFVKFTEVRGMTQLNDAPPRPITV
LGPYTFSIEDTTGYDEYLSGGYVVEVKPPKTLRFLSLQESLKQPTWTDADFGKLERPPQL
HLGFHALALWTERHGGSYPLPYHHEHALEVVELAKELNASAKLVETVDEKLISLLAYGSR
GEISPMVSFIGGVVAQEVLKACSGKFTPIHQWLYFDAVEALPTDLTPAHFQPEGTRYDGQ
VAVLGREVQRRLEAQRYFLVGSGAIGCEVLKIWASMGLGAGSGAIHVTDMDMIEKSNLNR
QFLFRPKDVGRLKSEAAAEAVRGMNGAINVRAYSARVGPETENVFDENFYESLTGVCNAL
DNVEARMYMDSQCIYHRKPMLESGTLGTKGNTQARALLLLLLPPPIALFEHHLTQRLPTC
VVVPMLTESYSSSRDPPEKSIPVCTLHHFPNKIEHTIHWSRDLFEGYFKNAADHVNAYLS
QPDFLEFLRKQPVVQQVEILNAIHGSLVSERPFTFDQCIAWARTRFEDLFRNNIAQLLYN
FPLDTITPSGAPFWSGPKRAPSPLTFNPDDRTHMDFIKSAANLRAANFGLKGSVEEGVFR
AALGQVTVPSFVPRKGVKIQTKEDAATKVEQSEGDEEQAARLLAELPAPSTLAGYRVSPL
IFEKDDDTNFHIDFIAAASNLRARNYSIAEVDKHTTKGIAGKIMPALVTTTALVAGLVCL
ELIKLVQGKDKLEDFRNGFVNLALPFFGFSEPIAPPVGTITEGWKWTLWDRFDVKGPSTL
RQLIELFESEHKLELSMASCGSTMLYSFFMPKSKLNERMDVEIAQLVETVTKKPLPENKK
YLTLEVVCSRLSDGEDVDVPPVRYQFRGL
NT seq 3150 nt   +upstreamnt  +downstreamnt
atggaggtggagcagaccagcacgatcgagcgcccaacaaccaacatcgacgaggggctc
tacagccggcagctgtatgtcctcaaccatgccgacatgctcaagatcaccgccaccgac
gtgctcatcgttggcctcaagggacttggcgttgagatcgccaagaacctggtgctggcc
ggcgtgcgcgccctcctgccgccttggccctgctatcggtgctcgcttgcggacccccac
ccgcagaacgtgggccactgcttcctgcgggagagcgacgtggggcgtgcgcgtgcggaa
gcgtgcgtggaccggctggccgagctcaacagctacgtgtccgtttcgctcctctcgcga
cccctcaacgcccagaccgtctcctccttctccgtggtggtggtgacggaggccgggtgg
ggccagaagctcgaggtgggcgagtggtgccacgagcggggcgtggcgttcgtgggcgcc
gaggcgcgcggcgtgttcgggagcgtgttctgcgactttggcgaggcccacacggtgctg
gaccccaacggggagccgcccttccagcagatgatcgcctccgtgacccgcgacaagccg
ggcgtggtcaccatcctcgacgaccggcgcctccagctcgagaccggcgatttcgtcaag
ttcaccgaggtgcgcggcatgacccaactcaacgacgccccgccccgccccatcaccgtg
ctcggcccctacaccttctcgatcgaggacaccacgggctacgacgagtacctctccggc
ggatacgtcgtcgaggtcaagccgcccaagaccctgcgcttcttgtcgctgcaagagtcg
ctgaagcagcccacgtggacggacgcggactttggtaagctggagcgtcctccgcagctg
cacctgggcttccacgccctcgccctctggaccgaacgccacggcgggtcctaccccctc
ccctaccaccacgagcacgccctggaagtggtggagctggccaaggagctcaacgcctcc
gccaagctggtggaaacggtggacgagaagctcatctcgctcctggcctacggctcccgc
ggagaaatctcgcccatggtgtcgttcatcgggggcgtggtggcgcaggaggtgctcaag
gcgtgttctggcaagttcacccccatccaccagtggctctacttcgacgccgtggaggcc
ctccccaccgacctcaccccggcacacttccagcccgaggggacgcggtacgacgggcag
gtggcggtgctggggcgcgaggtgcagcggcggctcgaggcccagcggtactttttggtg
gggtcgggcgccatcggctgcgaggtcctcaagatctgggcctccatgggcctgggcgcc
ggcagcggcgccatccacgtcaccgacatggacatgatcgaaaagtccaacctcaaccgc
cagttcctcttccgccccaaggacgtcggcaggttgaagtcggaggcggcggccgaggcg
gtgcgggggatgaacggggccatcaacgtccgggcctactcggcgcgggtgggacccgag
acggagaacgtgttcgacgagaacttctacgagtcgctgacgggcgtgtgcaacgccctc
gacaacgtggaggcccgcatgtacatggactcccagtgcatctaccaccgcaagcccatg
ctcgaatccggcaccctcggcaccaagggcaacacccaggcacgtgccctgctgctgctg
ctgctgcccccccccatcgctttgtttgaacatcacctcacccaacgtctcccgacttgt
gtggtggtgccgatgctgacggagtcgtactcgtcgtcgcgggatccgccggagaagagc
atcccggtgtgcacgctgcaccacttcccgaacaagatcgagcacaccatccactggtcg
cgggacctgttcgagggctacttcaagaacgcggccgaccacgtcaacgcctacctctcc
cagccggacttcctcgaattcctgcgcaagcagcccgtcgtgcagcaggtggagatcctc
aacgccatccacgggtccctcgtctccgagcggcccttcaccttcgaccagtgcatcgcg
tgggcccgcacccgcttcgaggacctcttccgcaacaacatcgcacagctcctctacaac
ttccccctcgacaccatcacaccctccggcgcgccgttctggtcggggccgaagcgagcg
cccagcccgctcacgttcaaccccgacgaccgcacccacatggacttcatcaagtccgcc
gccaacctgcgcgccgccaactttggcctcaaggggagcgtggaggagggcgtgttccgt
gcggccctgggccaggtgacggtaccgtccttcgtcccgcgcaagggcgtcaagattcag
accaaggaggacgccgccaccaaagttgaacaaagtgagggtgatgaggagcaggccgcg
cggctcctggcagagctgcccgccccgtccacgcttgccggctaccgcgtcagcccgctc
atcttcgagaaggacgacgacaccaacttccacatcgacttcatcgccgccgcctccaac
ctacgcgctcgcaactattcgatcgcggaggtggacaagcacacgaccaagggcattgcg
ggcaagatcatgccggccctcgtcaccacgaccgctctcgtggcgggcctcgtgtgcctc
gaactcatcaaactggtccagggcaaggacaagctcgaagacttcaggaacgggttcgtg
aacctggcgctgcccttcttcggcttttcggagccgattgcgccgcccgtgggcaccatc
acggaggggtggaagtggacgctgtgggaccgcttcgacgtgaagggtccgtcgaccctg
cgccagctcatcgaactgtttgagtccgagcacaagctggagctctccatggcctcgtgc
ggcagcaccatgctctactccttcttcatgcccaagtccaagctcaacgaacgcatggac
gttgagatcgcccaactggtggagacggtgacgaagaagcccctgcccgagaacaagaag
tacctcaccctcgaggtggtctgctcccgcctctccgacggcgaagacgtagacgtgccc
cccgtgcgctaccagttccgcggcctgtga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (93)   
   KEGG ORTHOLOGY (1)   
   RefGene (89)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (108)   

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