KEGG   Acidiphilium cryptum: Acry_0534
Entry
Acry_0534         CDS       T00527                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
acr  Acidiphilium cryptum
Pathway
acr00290  Valine, leucine and isoleucine biosynthesis
acr00620  Pyruvate metabolism
acr01100  Metabolic pathways
acr01110  Biosynthesis of secondary metabolites
acr01210  2-Oxocarboxylic acid metabolism
acr01230  Biosynthesis of amino acids
Module
acr_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:acr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Acry_0534
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Acry_0534
Enzymes [BR:acr01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Acry_0534
SSDB
Motif
Pfam: HMGL-like LeuA_dimer MR_MLE_C
Other DBs
NCBI-ProteinID: ABQ29758
UniProt: A5FVX6
Position
594890..596464
AA seq 524 aa
MTIHHPNFGAVPDDRVFIFDTTLRDGEQSPGFSMNLDEKLRMAEALAELGVDVIEAGFPI
ASQGDFESVRRIAETIKGPVIAGLARSGRDDIVRAGEAVKPAERKRIHTFISTSPLHMKY
KLRMEPDAVLEAVVRSVTLARDYTDDVEWSAEDGSRTEPDFLCRCVEAAIRSGATTINIP
DTVGYAVPEDIARIFTMLRERVPGADAVIFSTHNHNDLGLAVANTIAAIKAGARQIECTI
NGIGERAGNAALEEIVMAIRTRHDAVPYRNNIDTPRILRTSKLLATITGFDVQPNKAIVG
RNAFAHESGIHQDGVLKNAATYEIMTPESVGWQKTSLVLGKHSGRAAFRDKLRALGYGEV
GDNALNDAFRRFKDLADRKKLVYDEDIAALFDETVLRDQSRIRFVALEVWAGSKAKPRAR
LELEVDGEMKVHESHGDGPVDATFNAIRAICPHEAELKLFTVGAVTEGTDAQAKCGVRLE
ENGKSVDGQGSDTDTIVAAARAYVHALNKLIVKRERKEPAALTA
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgacgatccatcacccgaatttcggcgcggtccccgacgatcgcgtgttcatcttcgac
accaccctgcgcgatggcgagcagtcgcccggcttctcgatgaatctcgacgagaagctg
cgcatggccgaagccctcgccgaactcggcgtcgacgtcatcgaggccggcttcccgatc
gcgagccagggcgatttcgaaagcgtgcgccgcatcgccgaaaccatcaaggggccggtc
atcgccggcctcgcccgctccggccgcgacgacatcgtccgcgccggcgaggcggtgaag
ccggccgagcgcaagcgcatccacaccttcatctccacctcgccgctgcacatgaaatac
aagctgcggatggagcccgacgcggtgctcgaggcggtggtccgctccgtcaccctcgcc
cgcgactataccgacgacgtcgagtggtcggccgaggatggcagccgcaccgagcccgat
ttcctctgccgctgcgtcgaggcggcgatccgctccggcgcgacgacgatcaacatcccc
gacacggtcggctacgccgtgccggaagacatcgcgcggatcttcaccatgctgcgcgag
cgcgtccccggcgccgatgcagtgatcttctcgacccacaaccacaacgatctcggcctc
gccgtcgccaacaccatcgccgcgatcaaggccggcgcgcgccagatcgaatgcaccatc
aacggcatcggcgagcgcgccggcaatgccgcgctggaagagatcgtgatggcgatccgc
acccggcacgacgcggtgccctaccgcaacaatatcgacacgccgcgcatcctgcgcacc
tccaagctgctcgccaccatcaccgggttcgacgtgcagcccaacaaggcgatcgtcggg
cgcaacgccttcgcgcatgaaagcggcatccaccaggatggcgtgctgaagaacgccgcg
acctacgagatcatgacgcccgaatcggtcggctggcagaagaccagcctcgtgctcggc
aagcattccggccgcgccgccttccgcgacaagctgcgcgccctcggctatggcgaggtc
ggcgacaacgcgctgaacgacgccttccgccgcttcaaggacctcgccgaccgcaagaag
ctggtctacgacgaggacatcgccgccctgttcgacgaaacggtgctgcgcgaccagagc
cgcatccgcttcgtcgcgctggaagtctgggccggctcgaaggcgaagccccgcgcccgg
ctcgaactcgaggtcgatggcgagatgaaggtgcacgaatcgcatggcgacggcccggtc
gatgccaccttcaacgccatccgcgcgatctgcccgcacgaggcggaactgaagctcttc
accgtcggcgccgtcaccgaaggtaccgatgcgcaggcgaaatgcggtgtgcgcctcgag
gaaaacggcaagagcgtcgatggccagggctcggataccgacacgatcgtcgccgccgcc
cgcgcctatgtccacgcgctcaacaagctgatcgtcaagcgcgagcgcaaggaaccggcg
gcgctgaccgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (31)   

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