KEGG   Actinomadura sp. WMMB 499: F7P10_19165
Entry
F7P10_19165       CDS       T06213                                 
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
  KO
K15314  enediyne polyketide synthase
Organism
actw  Actinomadura sp. WMMB 499
Pathway
actw01059  Biosynthesis of enediyne antibiotics
actw01100  Metabolic pathways
actw01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:actw00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    F7P10_19165
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:actw01008]
    F7P10_19165
Polyketide biosynthesis proteins [BR:actw01008]
 Polyketide synthase (PKS)
  Iterative type I PKS
   Bacterial type
    F7P10_19165
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C KR Acyl_transf_1 PS-DH adh_short PKS_DH_N adh_short_C2 PP-binding KAsynt_C_assoc Thiolase_N
Other DBs
NCBI-ProteinID: QFG22920
UniProt: A0A5J6U7X1
Position
complement(4362978..4368788)
AA seq 1936 aa
MRAAGGRTGAAVAAPARCRAHRAPRRRRGAAAGGAARRDARDARRGPVSAVDAAAIAVVG
IGCRYPDAAGPQRLWEMVLAGRRAFRPLPPERLNVDDYAGDGPDSTYARFAAVLEDWTFD
RARHRVPGSTYRVTDPTHWLALEVAADTLDDAGFPGGRGLDGDRAGVVLGNTLAGEFSRA
SLLRLRWPYVRRVVESALAGTALPPAERDALMARLADGFKEPFPEPTDESLVGGLANAIA
GRVCNHFDLRGGGYTVDGACASSLLAVTTACTALADGDLDLALAGGVDLSLDPFELVGFA
RVGALAATEMRVYDARPTGFLPGEGCGMVALMRLGDALDDGRTPLAIIRGWGVSSDGRGG
LTRPESDGQALAMRRAYARAGFGPETVPLFEGHGTGTEIGDHAELRALSEAQGGRRTLPP
AAIGSVKANIGHTKAAAGAAGLIKATLALHHQVIPPTVGCTREHELLRRPGAPLRTVPEA
TPWPRAPLRAAVSAMGFGGINTHIVLEGAAPPRRGAFTLTERRLARRPLDAEVFAFAAET
AADLAASLRRVADRADGISLAEHIDLAAALAESAAHAAPPFRAAVVAGDPRTLARRARRA
AQLLERSEHPPPAAVPGVYLGRGAPGRVGLLFPGQGAPVRTDAGALGALLPDVTDRFAGA
GGDPVDTAVAQPAIVRASLAGLRWLARIGVGAVGAVGHSLGEITALCWAGALPEEDGARL
AAARGRAMADTGEPGMGMVSLAAPPPAVAELIAGTRLAVAADNGAVQVVAGPVADLDAVL
DRAGHAGVTARRLDVGHAFHTAAVAAARPPLARLLRGVPLDRPRRPVHSTVTGGVLTPDD
DLRELLVRQVTEPVRFRAALAALATGCDLLVECGPGHSLSTLAQEITDVPVVTLDAGSAS
AEPVARATGALFAAGAVGDPKAFFAERFHRPFVIDRAPAFLANPCESAPRVPAGPPGPQE
AGGAAAPPGETRSDGAVPNGAGSDGGARDAVVRDATVPDGAAPAGERETGATAATGTGPL
DAVRDLVADALELPAEMIGDDDGLLSDLHLNSLRVMQLAVRAAERCGRAVPAAPPPLASA
SVADLAAAVAELPAADRSGGRTGGPPPGVEEWFRVLAEERRPVRLPGERDPRHWQIGGRG
PLRALAEPLLHTVAGAPPAHAVFLPEDPGDAAIDALLEAASDALAASAPLTVVDLGVTAS
GLVGGLAQEHPDRDLRWIGVDAATGAAARTVADALATPHRGHTELLVGAGGETAEPVHRP
VRLASGEPPLAPGDVLLVTGGGRGIGLETAAALGDRWGVRLALLGRADPAHDADLRAGLD
RLEAGGTVVRYEAADVADPAAVRAAITRITGALGPVRGVVHGSAINRPARFAELSARDFA
AHAAPKHHGLRTLLGALDPSGLRLLVTYGSVIGRFGLPGEAHYALANGRLRELARVLAPE
LPGCRVRNIDWTAWSGAGMGERLDVLDGLAAGGVTPMPVEVGTRLAARIAESGTAATVLA
TGRLPALHTTDAGTGDGSFRRVRTHTPGVELVAETELSLRDAPEFDDHRIDGLAVLPAVS
ALEVMARAASALTGRPATAVAGGAFERPIIIPEDGARTVRACALARPDGDVAVVLRSDET
DFAVDHFSGTVTGPAAPPAVRRVDGVPGPHDGRSLYGPLFFHGPRFRRLVRFERLSATGC
TALLEAGEAGPWSLGDPARNDAAVHVLQACVPNRRLLPVGCARFTVHGDGSGELTLDAAE
RSHDGAEYVYDVLLADAAGRPVLSWTGLRLHDVGPLHAERGLPAAVVGVHLERGLAGLLP
GVRLTMEGLVPSVSGGAVVMGEVECGENGCEEAEHGGDGFGDAGRRAQADRLRRLTGESP
ARVRARMRTVEACLRKAGHDPRTQLAVQGVYEDGWAALRTRGGHRIVSVLLAVEGRPGPV
AVAIAADGVPAEGRRA
NT seq 5811 nt   +upstreamnt  +downstreamnt
gtgcgcgctgcggggggccggactggggctgctgtcgctgcgccggcgcgctgccgagcg
caccgcgccccgcgccggcgccgcggcgccgcggcaggcggtgctgcccggcgcgacgct
cgcgacgcccgacgaggcccggtgagcgccgtggacgccgccgcgatcgccgtcgtcggg
atcggctgccggtaccccgacgccgccggcccgcagcggctgtgggagatggtcctggcg
ggccggcgcgcgttccggccgctcccgcccgagcggctgaacgtggacgactacgctggc
gacggcccggactcgacgtacgcgcggttcgccgccgtcctggaggactggacgttcgac
cgcgcccgccaccgcgtgcccggatccacgtaccgggtcaccgacccgacccactggctc
gcgctggaggtcgccgcggacacgctggacgacgccgggttccccggcgggcgcgggctg
gacggggaccgcgcgggcgtggtgctgggcaacacgctcgccggcgagttcagccgggcg
tcgctgctgcggctgcggtggccgtacgtacggcgcgtggtggagtccgcgctggccggg
acggccctgcccccggccgagcgggacgccctgatggcgcgcctggcggacgggttcaag
gagccgttccccgagccgacggacgagagcctggtcggcgggctggccaacgccatcgcg
ggccgggtgtgcaaccacttcgatctccgcggcggcggctataccgtcgacggcgcctgc
gcgtcgtcgctgctggcggtcaccacggcgtgcacggcgctcgcggacggcgacctggac
ctggcgctggccgggggagtggacctgagcctcgacccgttcgagctggtcggcttcgcc
cgggtgggcgcgctggccgcgacggagatgcgggtctacgacgcgcggcccaccggcttc
ctgccgggggagggctgcggcatggtcgcgctgatgcgcctcggcgacgcgctggacgac
gggcggaccccgctggccatcatccgcggctggggcgtttcgtccgacgggcgcggcggc
ctgacccggccggagagcgacgggcaggcgctggccatgcgccgcgcctacgcccgcgcc
ggcttcggacccgagaccgtgccgctgttcgaggggcacggaaccggcaccgagatcggc
gaccacgccgagctgcgcgcgctgagcgaggcgcagggcggccgccgcacgctaccgccc
gcggcgatcgggtccgtgaaggcgaacatcgggcacaccaaggcggcggcaggtgccgcg
gggctgatcaaggccacgctcgcgctgcaccaccaggtgatcccgccgaccgtcggctgc
acccgggaacacgagttgctgcgccgccccggggcgccgctgcggaccgtcccggaggcg
accccctggccgcgggccccgctgcgggccgcggtgagcgccatggggttcggcggcatc
aacacccacatcgtgctggagggcgccgcgcccccgcggcgcggcgcgttcacgctcacc
gagcggcggctggcccgccgcccgctggacgccgaggtgttcgccttcgcggcggagacc
gccgccgacctcgccgcgtcgctgcggcgggtggcggaccgcgcggacggcatctcgctg
gccgagcacatcgacctggccgcggccctcgccgagtccgccgcgcacgcggcgccgccg
ttccgcgccgccgtcgtcgccggcgacccccggacgctggcgcggcgggcgcgccgggcc
gcgcagctcctggaacggtcggagcacccgccgccggccgccgtcccgggcgtctacctg
gggcggggcgcgccgggcagggtcggtctcctgttccccgggcagggcgccccggtccgc
acggacgccggagccctcggcgcgctgctgccggacgtgacggaccgcttcgccggcgcc
ggcggcgaccccgtggacaccgccgtggcgcagcccgcgatcgtccgggcgtccctggcc
gggctgcgctggctcgcccggatcggcgtcggcgcggtcggcgcggtcggccacagcctc
ggcgagatcaccgccctgtgctgggcgggcgcgctccccgaggaggacggcgcccggctg
gccgcggcgcgcggccgcgccatggccgacaccggggagccgggcatgggcatggtctcg
ctcgccgccccgccgccggcggtcgccgagctcatcgcgggaacccggctcgcggtggcg
gccgacaacggcgccgtgcaggtcgtcgccggcccggtcgccgatctggacgcggtgctg
gaccgggccgggcatgccggcgtcaccgcccggcggctggacgtcggccacgccttccac
accgccgcggtcgccgcggcgcgcccgccgctcgcgcgcctgctgcgcggcgtgccgctg
gaccgcccgcggcggccggtgcactccacggtcaccggaggcgtcctcaccccggacgac
gacctgcgcgaactgctcgtccggcaggtcaccgagccggtccggttccgcgccgcgctg
gcggcgctggcgaccggctgcgacctcctggtcgagtgcggccccgggcactccctcagc
accctggcccaggagatcaccgacgtacccgtggtgacgctggacgcgggctcggcttcg
gccgagccggtggcgcgggcgaccggcgcgctgttcgcggcgggcgcggtcggggacccg
aaggcgttcttcgccgagcggttccaccgcccgttcgtcatcgaccgcgcgccggccttc
ctcgccaacccctgcgagagcgccccgcgcgtgccggcgggtccccccggcccccaagag
gccggcggagccgcggccccgcccggcgagacccgctcggacggggcggtcccgaacggg
gccggctcggacgggggtgcgcgggacgcggtggtccgggacgcgaccgtcccggacgga
gcggccccggcgggcgagcgggagaccggcgcgaccgcggccaccggcaccggccccctg
gacgcggtccgcgacctggtcgcagacgccctcgaactgcccgccgagatgatcggcgac
gacgacgggctgctcagcgacctgcacctcaactcgctgcgggtgatgcaactggccgtc
cgggccgccgagcggtgcgggcgcgccgtcccggccgcgccgccgccgctggcgtccgcc
tccgtcgccgacctcgccgcggcggtcgcggaactgcccgcggccgaccgttccggcggc
cgcaccggcggcccgcccccgggagtggaggagtggttccgcgtcctcgccgaggagcgc
cgcccggtacggctccccggcgaacgcgacccccgccattggcagatcggaggccggggg
cccctccgcgccctcgccgaacccctgctccacaccgtcgccggcgcgccgcccgcgcac
gcggtgttccttcccgaagaccccggcgacgcggcgatcgacgcgctgctggaggcggcg
tcggacgccctcgccgcgagcgctccgctgacggtggtggacctcggcgtcaccgcgtcc
ggtctcgtcggcggcctcgcccaggagcatcccgaccgggatctgcgctggatcggggtc
gacgcggcgaccggggcggcggcccgcacggtcgcggacgcgctcgcgacaccccaccgc
ggccacaccgagctgctggtcggcgcgggcggagagacggccgaacccgtccaccgtccc
gtccggctcgcgtccggggagcccccgctggcccccggtgacgtgctgctggtgacgggc
ggcggccggggcatcggcctggagaccgccgccgccctcggcgaccgctggggcgtgcgg
ctcgccctcctcggccgcgccgatcccgcccacgacgcggacctgcgcgccggactggac
cgcctggaggccggcgggaccgtggtccgctacgaggccgcggacgtcgccgatccggcc
gcggtgcgcgccgcgatcacccgcatcaccggcgcactcggccccgtgcgcggcgtcgtg
cacggcagcgcgatcaaccggcccgcgcggttcgccgagctgagcgcccgggacttcgcc
gcccatgccgcgcccaagcaccacgggctgcggacgctcctcggcgccctcgacccgtcc
ggcctgcggctcctcgtcacctacggctcggtgatcggccggttcgggctgccgggggag
gcgcactacgccctcgccaacgggcgcctgcgcgaactcgcgcgggtgctggcgcccgaa
ctgcccggatgccgcgtccgcaacatcgactggacggcgtggtccggcgccgggatgggc
gaacgcctggacgtcctggacgggctggccgccggcggcgtcacgccgatgcccgtcgag
gtcggcacccgcctggccgcgcggatcgccgagtccggcacggcggcgaccgtcctggcc
accggcaggctgcccgcactgcacaccacggacgccgggaccggggacggatccttccgg
cgggtccggacgcacacgccgggcgtcgaactcgtcgccgagaccgaactgagcctgcgc
gacgcccccgagttcgacgaccaccgcatcgacgggctcgcggtcctgcccgcggtgagc
gcgctggaggtgatggcgcgggccgcgtccgcgctgacggggcggccggccacggccgtg
gccggcggcgccttcgaacgcccgatcatcatcccggaggacggggcccgcaccgtgcgg
gcgtgcgcgctggcccggccggacggcgacgtggcggtcgtgctgcgcagcgacgagacc
gacttcgccgtcgaccacttctccggcaccgtcaccggcccggccgcaccgccggccgtc
cggcgcgtcgacggcgtccccggtccgcacgacggccgctcactgtacggcccgctgttc
ttccacggtccgcgctttcggcggctcgtgcgcttcgaacgcctgtcggccaccggctgc
acggcgctcctcgaagccggggaggcgggaccgtggtcgctgggcgatccggcgcgcaac
gacgccgccgtgcacgtgctgcaggcctgcgtcccgaaccggcggctgctgcccgtggga
tgcgcccgcttcaccgtgcacggtgacggctcgggtgagctgaccctggacgccgccgag
aggtcgcacgacggcgcggagtacgtgtacgacgtcctgctcgcggacgccgccggacgg
cccgtgctgagctggaccgggctgcggctgcacgacgtcggcccgctgcacgccgagcgc
gggctgcccgccgcggtcgtcggcgtccacctcgaacgcggtctcgcgggcctgctgccc
ggcgtgcggctgaccatggagggcctcgtgccgtccgtgtccggcggcgccgtcgtgatg
ggcgaggtcgagtgcggtgagaacgggtgcgaggaggcggagcacggtggggacgggttc
ggcgacgccggacggcgggcccaggcggaccggctgcgcaggctgacgggcgagtccccg
gcgcgcgtccgcgcccgcatgcggaccgtcgaggcgtgcctgcggaaggcgggacacgac
ccgcggacgcagctcgccgtgcagggagtgtacgaggacggctgggcggcgctccggacg
cgcggcgggcaccggatcgtgtccgtcctgctggccgtcgagggaaggccgggcccggtc
gccgtcgcgatcgcggcggacggcgttccggcggaaggacggcgcgcatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (11)   
   Pfam (11)   
All databases (31)   

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