KEGG   Actinomyces sp. 432: CWT12_01820
Entry
CWT12_01820       CDS       T06433                                 
Symbol
topA
Name
(GenBank) type I DNA topoisomerase
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
actz  Actinomyces sp. 432
Brite
KEGG Orthology (KO) [BR:actz00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:actz03032]
    CWT12_01820 (topA)
   03400 DNA repair and recombination proteins [BR:actz03400]
    CWT12_01820 (topA)
Enzymes [BR:actz01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     CWT12_01820 (topA)
DNA replication proteins [BR:actz03032]
 Prokaryotic type
  DNA Topoisomerases
   CWT12_01820 (topA)
DNA repair and recombination proteins [BR:actz03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      CWT12_01820 (topA)
SSDB
Motif
Pfam: Topoisom_bac Toprim_C_rpt Toprim Toprim_4 Toprim_2
Other DBs
NCBI-ProteinID: QHO90332
UniProt: A0A7L5AT68
Position
440498..443452
AA seq 984 aa
MSTKLVIVESPNKVRSIAGYLGKDFDVEASVGHIRDLAQPSELPAAEKKGPYSKFAVDVT
DGFKPYYVVNPDKKKTVTQLRKALKDADELYLATDDDREGEAIAWHLLEVLKPKVPVKRM
TFTEITKEAVTRALSNTRDLDTHRVDAQETRRILDRLVGYEVSPVLWRKVRAGLSAGRVQ
SVATRLVVERERERMAFKPAGYWGVEAQLSTDLAAGSSLRPTAVDSSFTARLTALDGRRV
ATGRDFTDAGVLRPAAVKAGTVHLHEGAARAVADAITRAVPRVAEVEDKPYRRRPAAPFT
TSTLQQEASRKLRMNPRETMRVAQALYENGFITYMRTDSTVLSGQAVAAARSQVAELYGA
EYVAPKPRVYATKTKGAQEAHEAIRPAGDHFRTPAQVSGQLTGAQFRLYELIWRRTVASQ
MADATGSTATVRVDVPLRPADGGSRDAGITFSTASLSASGTVITFRGFLAAYEEGRDAER
YESENTPAVAGSADAAAAGEGAGAGGAAAAKAGKDREVRLPAMIAGQELAALAAEAAGHE
TTPPPRYTEASLVKALEEREIGRPSTYASIMSTISDRGYVEHRGQALVPTWLAFAVTRLL
EENFSELVDYDFTASMEADLDRIASGEEDRVDWLTHFYYGPQGQAGAGVNDAAASGPAPA
AAGPAGESQGLKALVDGLGEIDARAVNSIDIGEGITLRVGRYGPYLEDAEGKRANVPGDL
APDELTVAKAQELFIRAADDGRELGTDPSTGHTIVAKDGRYGPYVTEILPEPETGEAEAA
AGSASSRSGAKTARRARKGPKPRTASLFKSMDLATVTLEQALDLLSLPRVVGQDAEGVDI
TAQNGRYGPYLKRGTDSRSLESEEQLFTVTLEQALELFAQPKRRRGQAAARGPLRELGTD
PATGRPVVIKDGRFGPYFTDGETNVTLRRDDDPATVTPERAYELLAEKRAKGPAKKRTTR
KTTAKRTTAKRPTAKKSTTSKTSG
NT seq 2955 nt   +upstreamnt  +downstreamnt
gtgtccaccaagctcgtcatcgtcgagtcccccaacaaggtccgctccattgccggatac
ctgggcaaggacttcgacgtcgaggcctcggtcggccatattcgtgacctggcccagccg
tccgagctgcccgcagccgagaagaagggcccgtacagcaagttcgctgtcgacgtaacc
gacggattcaagccctactacgtggtcaacccagacaagaaaaagacggtcacgcagctg
cgcaaggccctcaaggacgccgacgagctctacctggccaccgatgatgaccgcgagggg
gaggccatcgcctggcacctgctggaggtgctcaagcccaaggtgccggtcaagcgcatg
accttcaccgagatcaccaaggaggcagtcacccgcgccctgagcaacacgcgtgacctg
gacacgcaccgggtggacgcccaggagacccgccgcatcctggaccggctggtcggctac
gaggtcagccccgtgctgtggcgcaaggtgcgtgccggcctgtccgccgggcgcgtgcag
tcggtggccacgcgcctggtggtcgagcgtgagcgcgagcgcatggccttcaagcccgcc
ggctactggggagtggaggcccagctgtccaccgacctggccgccggcagctcactgcgg
cccaccgcggtggacagctcgttcactgcgcgcctgaccgccctggacggacggcgcgtg
gccacaggacgtgacttcaccgacgccggggtactgcggcctgccgccgtcaaggcggga
accgtgcacctgcacgagggggccgctcgcgccgtcgccgacgccatcacccgcgccgtg
ccgcgcgttgccgaggtggaggacaagccctaccggcggcgcccggcggcacccttcacc
acctccaccctgcagcaggaggcgagccgcaagctgcgcatgaacccgcgcgagaccatg
cgggtggcgcaggccctgtatgagaacggcttcatcacttacatgcgtaccgactccacg
gtgctgtccgggcaggccgtcgccgccgctcgcagtcaggtggccgagctgtacggcgcg
gagtacgtcgcgccgaagccgcgcgtgtacgccaccaagaccaagggtgcccaggaggcc
cacgaggcgatccggcccgccggcgaccacttccgcacccccgcccaggtgtccggccag
cttaccggcgcccagttccgactgtacgagctgatctggcggcgcacggtcgcctcccag
atggccgatgccaccggctccacggctaccgtgcgggtggacgtgccgctgcgccccgcg
gacggcggctcccgcgatgccggcattaccttcagcactgcctccctcagcgcctcgggc
acagtcatcaccttccgtggcttcctggccgcatacgaggaggggcgtgatgctgagcgc
tacgagtcggagaacacgcccgcggtggcgggcagcgccgatgccgctgcggcgggtgag
ggcgccggagccggcggggccgccgccgcgaaggcgggcaaggaccgggaggtgcgcctg
ccggccatgatcgccgggcaggagctggccgcactggctgccgaggccgccgggcacgag
accacgccgccgccccgctacacggaggcctccctggtcaaggccctggaggagcgggag
atcggccggccgtccacgtacgcctccatcatgtccaccatctccgaccgcggttacgtt
gagcaccgtggccaggcactggtgcccacctggctggccttcgcggttacccggctgctg
gaagagaacttcagcgagctggtcgattacgacttcaccgcctccatggaggcagacctg
gaccgtatcgcctccggcgaggaggaccgggtcgactggctcacccacttctactacggg
ccgcaggggcaggcgggtgcgggcgtgaacgacgctgcggcgtcgggaccggcgcccgcg
gcagcggggcctgcgggggagagccaggggctcaaggccctggttgacgggctgggtgag
atcgatgcccgcgccgtcaactctattgacatcggtgagggcatcaccctgcgcgtgggc
cgctacgggccctacctggaggacgccgagggcaaacgcgccaatgtgcccggcgatctg
gcgcccgacgagctaaccgtggccaaggcgcaggagttgttcatccgcgctgccgatgac
gggcgcgaactcggcaccgacccgtccaccgggcacaccatcgtggctaaggatggccgt
tacggcccctatgtcaccgagatcctgcctgagccggagaccggtgaggcggaggctgcg
gccggctcggcgtcgtcgaggagcggtgccaagactgcccgccgggcccggaagggaccc
aagccgcgtactgcctcactgtttaagtcgatggacttggccaccgttaccttggaacag
gccctcgacttgttgagcctgccgcgcgtggttggccaggacgccgaaggtgttgacatc
acggcgcagaacggtcgctacgggccctacctgaagcggggcactgactcgcgctccttg
gagagcgaggagcagctgttcacggtgaccctggagcaggcgctggagctgttcgcccag
cccaagcggcgccgtggtcaggcggctgcccgcggccccctgcgggaactcggcaccgat
ccggccacggggcgtccggtggtgatcaaggacggccgcttcggcccgtacttcaccgat
ggggagacgaacgtgacgctgcgtcgtgatgatgacccggccacggtcactcccgagcgc
gcctatgagctgctggcggagaagcgcgctaaggggccggccaagaagcgcactacccgt
aagaccacggcgaagagaaccactgccaagaggccgaccgcgaagaagtccaccaccagt
aaaacgagcggctga

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (14)   

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