KEGG   Athene cunicularia (burrowing owl): 113476436Help
Entry
113476436         CDS       T05777                                 

Gene name
ROCK1
Definition
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.1]
Organism
acun  Athene cunicularia (burrowing owl)
Pathway
acun04270  Vascular smooth muscle contraction
acun04350  TGF-beta signaling pathway
acun04510  Focal adhesion
acun04530  Tight junction
acun04810  Regulation of actin cytoskeleton
acun05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:acun00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    113476436 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113476436 (ROCK1)
   04530 Tight junction
    113476436 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    113476436 (ROCK1)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    113476436 (ROCK1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113476436 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:acun01001]
    113476436 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:acun03036]
    113476436 (ROCK1)
Enzymes [BR:acun01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     113476436 (ROCK1)
Protein kinases [BR:acun01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   113476436 (ROCK1)
Chromosome and associated proteins [BR:acun03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    113476436 (ROCK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Rho_Binding PH C1_1 APH Cortex-I_coil HR1 Pkinase_C DUF1192
Motif
Other DBs
NCBI-GeneID: 113476436
NCBI-ProteinID: XP_026697844
Position
2
AA seq 1358 aa AA seqDB search
MSTGESFESRFEKIDVTLKDPKSEVNVDCLLDGLDALVYDLDFPALRKNKNIDNFLNRYK
DTVNKMRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRRVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNEISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLAVSAENSNDNRTGS
SVDKSVLENMQKMIYELEEQLHNEMQLKDEMEQKCRSSNIKLDKIMKELDEEGNQRKNLE
STVSQIEKEKMVLQHKINDYQRKIEQENEKRRNIENEVSTLKDQMEDLKKISQHSQITNE
KITQLQKQLEEANDLLRTESDTAARLRKGNTEMSKSLSQVESLNRELQERCRVLESTKLQ
VEKDYYQLQAALESERRDRSHGSEMIGELQVRITTLQEEVKNVKNNLERVEAERKQAQDM
LNHSEKEKNNLEIDLNYKLKSLQDRLEQEVNEHKVTKARLTDKHQSIEEARSVAMCEMEK
KVKEERAAREKAENRIVQAEKQCSMLDFDLKQSQQKLEHLLEQKERLEEEVRNLTLKLEQ
ETNKRIMAQNDLKAQAFEADNLKGSEKQLKQEINTLLEAKRLLEFELAQLAKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIDEKNKETQRKMQELQNEKETLTTQLDLAETK
AESERLARALLEEQYFELSQESKKAASRHRQEMTDKDSIIRRLEETNNTLTKDVDLITKE
NSEISEKIKKQEEEYKMKKEEEINNIRMHYEKSINTERTLKTQAVNKLAEIMNRKDFKID
RKKANMQDLRKKEKENRKLQLELNQEKEKFNQMVVKYQKELNEMQAQLAEESTYRNELQM
QLDSKESDIEQLRRKILDLQQGMDSTSVASLQTDETDGNLSESRLEGWLSIPNKGNIKRH
GWKKQYVVVSSKKILFYNDEKDKDQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIF
QILYANEGECRKDLEVEAVQPAEKTNFLNHKGHEFIPTLYHFPANCEACAKPLWHVFKPP
AALECRRCHVKCHRDHLDKKEELIAPCKVSYDVTSARDMLLLASCQDEQKKWVTHLVKKI
PKTPPSTFVRASPRTMSTRSSANQSFRKVVKNTSGKTS
NT seq 4077 nt NT seq  +upstreamnt  +downstreamnt
atgtcgacgggagaaagttttgagtctcggtttgaaaaaatcgacgtgactttaaaggac
cccaaatccgaagtgaacgtggactgtttgctggatggattagatgctttggtatatgac
ttggattttcctgccttaagaaaaaacaaaaatattgataacttcttaaacaggtataaa
gacacggtaaataaaatgagagatctgcgcatgaaagctgaagattatgaagtggtgaag
gtgatcggtagaggggcatttggagaggttcagctggtaaggcataaatcctcaaggaga
gtgtatgctatgaagcttctgagcaaatttgaaatgataaaaagatcagattctgcattc
ttctgggaggaaagggatattatggcctttgctaacagtccctgggttgttcagttattt
tatgcattccaagatgaccgttacctttacatggtgatggaatacatgcctggtggggac
ctggtgaatttaatgagcaactacgatgttccagagaaatgggcaagattttatactgct
gaagttgtacttgcattagatgcaattcactcaatgggttttattcacagagatgtgaag
cctgataatatgctgctagataaagctggtcatttaaaactagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacggctgtgggaacaccagactat
atctctcctgaagtattgaagtctcagggtggtgatggttactatgggcgagaatgtgac
tggtggtcagttggagtctttttgtatgagatgcttgtaggtgatacacctttttatgca
gattctttggttggaacatacagtaagattatgaaccataagaactcccttactttccct
gatgacaatgagatttctaaagaggcaaaaaaccttatttgtgcttttttaacagatagg
gaagtgaggctaggacgaaatggtgtagaagaaattaaacgacaccttttcttcaaaaat
gatcagtgggcttgggaaactctcagagacactgtagcaccagttgtgcctgacttgagt
agtgacattgacactagtaattttgatgatctggaagaagacaaaggggaggaagaaaca
tttcctataccgaaagcatttgtgggcaaccagcttccttttgtaggatttacgtactac
agcaaccgtcggtatttagctgtctctgcagaaaattccaatgataacagaacaggctcc
agtgtggacaaaagtgtgctggaaaatatgcagaagatgatctatgagttggaagaacaa
ctacataatgaaatgcagttgaaagatgaaatggagcaaaagtgcagatcttcaaacata
aagctagacaagataatgaaagaactggatgaagagggaaatcaaagaaagaacttggaa
tcaacagtgtctcagattgagaaggaaaagatggtattacaacataagataaatgactac
caaagaaaaattgaacaagagaatgaaaaaagacggaatatagaaaatgaagtgtccacg
ctaaaagatcagatggaagacttgaaaaaaatcagccagcattcacaaattacaaatgag
aagataacacaattacaaaagcaactagaagaagcaaatgatttgctgaggacagaatcg
gatacagcagcaagactgagaaagggtaacacagaaatgagcaagtcattaagtcaggta
gaatcactgaatagagaactgcaagaaaggtgtagagttctagaaagcacaaaactgcag
gtggagaaagattattaccaactgcaagcagctttggagtcggaacgaagggacagaagt
catggatctgaaatgattggagaactacaggttcggattacaactttacaagaagaagta
aaaaacgttaaaaacaatctcgaaagagtggaagcagaaagaaaacaagcacaggatatg
cttaatcattcagaaaaggaaaagaataatttagagatagatttgaactacaaactcaaa
tcattacaagaccggttagaacaggaagtaaatgaacacaaagtgactaaagctcgatta
actgacaaacatcagtcaatagaggaggcaagatcagttgcaatgtgtgaaatggaaaaa
aaagtgaaggaagaaagggcagcaagagaaaaggcagaaaatcgtatagttcaagctgaa
aaacagtgttccatgctggactttgacctcaagcaatctcagcagaaactggaacacctt
cttgagcaaaaagagagactggaagaggaagtaaggaatctaacacttaagctagaacaa
gagacgaacaagcgaataatggcacagaatgacttaaaggcacaagcttttgaagcagat
aacttgaagggttctgagaagcagctgaaacaggaaatcaatacgttgttggaagcaaag
aggttactggaatttgagttggctcaacttgctaaacagtacagaggaaatgaaggtcaa
atgcgtgagcttcaggatcagcttgaggctgagcagtatttttcgacactttacaaaact
caggttaaggaactgaaagaagaaattgatgaaaagaataaagaaactcaaagaaaaatg
caggagttgcaaaatgaaaaagaaacactcactacccagttggatttagctgaaaccaag
gctgagtcagaacggttggcacgagcactccttgaagaacagtattttgaactaagtcag
gaaagcaaaaaagcagcatcaagacacaggcaagaaatgactgataaggacagcatcata
agaaggctggaagaaactaataacacattaaccaaagatgttgatttaataacaaaggaa
aattcagagatcagtgaaaaaattaagaaacaggaagaagaatataaaatgaaaaaagag
gaggagatcaataatattagaatgcattatgagaagagcattaacactgaaagaactctg
aagacacaggctgtcaacaagctggctgagataatgaatcggaaagattttaaaatagac
agaaagaaagctaatatgcaagatttgaggaagaaagagaaggaaaatcgaaagctccaa
ttagagcttaatcaagaaaaagagaaattcaatcagatggtagtgaaataccaaaaggaa
ctcaatgaaatgcaagcgcaactggcagaagaatctacatacaggaatgagctccagatg
cagctggatagtaaagagagtgacatagaacaactacgaaggaaaattttggacctccag
caaggaatggattctaccagtgttgctagtctccagacagatgaaacagatggaaatctt
tcagaatcaagacttgaaggttggctttcaataccaaacaaaggaaatataaagcggcat
ggctggaagaaacagtatgttgtggtgagcagtaaaaagatactgttctacaatgacgaa
aaggataaggaccagtctaatccatccatggtactagatatagataagctgttccatgtc
cgccctgttactcaaggagatgtatatagagctgaaactgaagaaattcctaaaatattc
cagattctctatgctaatgagggggaatgcaggaaggatttggaggtagaagcagtacag
ccagcagagaagacaaattttctaaatcacaaaggccatgaatttattccaacattatac
cactttccagccaactgtgaggcctgtgccaaacctctttggcatgtctttaaaccccct
gctgccctagaatgtcgaagatgccatgtgaagtgccacagagaccacctggataaaaag
gaggaattaattgcaccatgcaaagtgagttacgatgtaacttcagcaagagatatgctg
ttattggcatcctgtcaagatgaacagaagaaatgggtgactcatttagtaaaaaagatc
cctaagacaccaccgtctacttttgttcgtgcttctcctagaactatgtctacaagatcc
tcagcaaatcagtcattccgaaaagttgttaaaaatacttctggaaaaactagctaa

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