Entry
Symbol
vanX
Name
(KEGG) D-Ala-D-Ala dipeptidase (EC:3.4.13.22)
KO
Taxonomy
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Organism
Enterococcus faecium
Taxonomy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
Structure
PDB
AA seq
202 aa AA seq DB search
MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYELAESLLKAKELAATQ
GYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRTEMISKGYVASKSSHSRGS
AIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNRRRLRSIMENSGFEAYSL
EWWHYVLRDEPYPNSYFDFPVK
Reference
Authors
Arthur M, Molinas C, Depardieu F, Courvalin P
Title
Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.
Journal
Reference
Authors
Reynolds PE, Depardieu F, Dutka-Malen S, Arthur M, Courvalin P
Title
Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine.
Journal