KEGG   Addendum: AAU00079
Entry
AAU00079          CDS       T10000                                 
Symbol
phpD
Name
(KEGG) 2-hydroxyethylphosphonate dioxygenase (EC:1.13.11.72)
  KO
K12905  2-hydroxyethylphosphonate dioxygenase [EC:1.13.11.72]
Taxonomy
TAX:1938
  Lineage
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces viridochromogenes
SSDB
Motif
Pfam: Cupin_2 HTH_31 HTH_26 DUF2379
Other DBs
NCBI-ProteinID: AAU00079
GB: AY632421
UniProt: Q5IW40
Structure
AA seq 443 aa
MRIDPFKLAHWMNARKYTAAQTADLAGLPLDDLRRLLGDEANEPDPAAATALAEALSVEP
SQLAADAHRNLTVVHKSAEEMHASRRPIQRDGIHFYNYYTLAAPEGRVAPVVLDILCPSD
RLPALNNGHLEPAITVNLGPGDINGRWGEEITPQTWRVLHANHGGDRWITGDSYVEPSYC
PHSYSLAGDAPARIVSYTAQSNISPLMTEANNWSTGAFEEALKALSGKVSAGSVLDLFLA
RRAHTRTSAAEAAGVPPADLEAALRSPASETGLTVLRTLGRALGFDYRVLLPADDQHDGV
GKTWTTIEDSRRSRRTFGTYEAASMASAAHLPDLVGSFLRVDADGRGADLIDHAENHYVV
TEGRLTLEWDGPDGPASVELEPDGSAWTGPFVRHRWHGTGTVLKFGSGAHLGYQDWLELT
NTFEPAATLRRGRRDLAGWGYDN
Reference
  Authors
Blodgett JA, Zhang JK, Metcalf WW
  Title
Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736.
  Journal
Antimicrob Agents Chemother 49:230-40 (2005)
DOI:10.1128/AAC.49.1.230-240.2005
Reference
  Authors
Blodgett JA, Thomas PM, Li G, Velasquez JE, van der Donk WA, Kelleher NL, Metcalf WW
  Title
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.
  Journal
Nat Chem Biol 3:480-5 (2007)
DOI:10.1038/nchembio.2007.9
Reference
  Authors
Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW
  Title
An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis.
  Journal
Nature 459:871-4 (2009)
DOI:10.1038/nature07972

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