KEGG   Antarctobacter heliothermus: ANTHELSMS3_01275
Entry
ANTHELSMS3_01275  CDS       T04983                                 
Symbol
lpdA
Name
(GenBank) dihydrolipoyl dehydrogenase
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
aht  Antarctobacter heliothermus
Pathway
aht00010  Glycolysis / Gluconeogenesis
aht00020  Citrate cycle (TCA cycle)
aht00260  Glycine, serine and threonine metabolism
aht00280  Valine, leucine and isoleucine degradation
aht00310  Lysine degradation
aht00380  Tryptophan metabolism
aht00620  Pyruvate metabolism
aht00630  Glyoxylate and dicarboxylate metabolism
aht00640  Propanoate metabolism
aht00785  Lipoic acid metabolism
aht01100  Metabolic pathways
aht01110  Biosynthesis of secondary metabolites
aht01120  Microbial metabolism in diverse environments
aht01200  Carbon metabolism
aht01210  2-Oxocarboxylic acid metabolism
aht01240  Biosynthesis of cofactors
Module
aht_M00009  Citrate cycle (TCA cycle, Krebs cycle)
aht_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
aht_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
aht_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:aht00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    ANTHELSMS3_01275 (lpdA)
   00020 Citrate cycle (TCA cycle)
    ANTHELSMS3_01275 (lpdA)
   00620 Pyruvate metabolism
    ANTHELSMS3_01275 (lpdA)
   00630 Glyoxylate and dicarboxylate metabolism
    ANTHELSMS3_01275 (lpdA)
   00640 Propanoate metabolism
    ANTHELSMS3_01275 (lpdA)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    ANTHELSMS3_01275 (lpdA)
   00280 Valine, leucine and isoleucine degradation
    ANTHELSMS3_01275 (lpdA)
   00310 Lysine degradation
    ANTHELSMS3_01275 (lpdA)
   00380 Tryptophan metabolism
    ANTHELSMS3_01275 (lpdA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    ANTHELSMS3_01275 (lpdA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:aht04147]
    ANTHELSMS3_01275 (lpdA)
Enzymes [BR:aht01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     ANTHELSMS3_01275 (lpdA)
Exosome [BR:aht04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   ANTHELSMS3_01275 (lpdA)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Biotin_lipoyl Pyr_redox FAD_oxidored Pyr_redox_3 Biotin_lipoyl_2 NAD_binding_8 GIDA AlaDh_PNT_C FAD_binding_2 HI0933_like GCV_H DAO Thi4 FAD_binding_3 HlyD_D23
Other DBs
NCBI-ProteinID: ASP19986
UniProt: A0A222E1C4
Position
1345934..1347670
AA seq 578 aa
MDVKVPDIGDFADVPVVAVLVSVGDMVSEEDPLIELESDKATMEVPSPAAGKVTEIKVKE
GDRIGEGAVILVLEGADAKDEAPKAEAPAAEAPKQVSATGTASGPGDVHAEVVVLGSGPG
GYTAAFRAADLGKKTVLIEKFDRLGGVCLNVGCIPSKALLHVAKVITEAEEMGAHGISFS
KPGIDLDELRAFKDSVVGKLTGGLDGLSKGRKVQVVRGYGKFSGPNMIEVQGDDGVTTVS
FDQCIIAAGSEPVALPFIPHDDPRVIDSTGALELADIPGRMLVLGGGIIGLEMACVYDAL
GSKITVVELMDQIIPGADKDIVKPLMTRIKGRYENIFLKTKVTAVEALDEGMKVTFEDDK
GESFSDTFDKVLVAVGRKPNGKLIDADKAGVAVDDRGFIAVDKQQRTGVPHIFAIGDVVG
QPMLAHKAVHEGKVAAEVCAGHKRFFDAQLIPSVAYTDPEVAWCGVTENDAKAKGIKYEK
GVFPWAASGKSLSNGRSEGITKLLFNPDDDRIIGACIVGTNAGDLISEAALAIEMGADAV
DLGHTIHPHPTLSETVNFAAEMFEGTITDLMPPKKRKH
NT seq 1737 nt   +upstreamnt  +downstreamnt
atggatgtcaaagtacccgatatcggtgatttcgccgacgtgcctgtggttgccgtactg
gtcagcgtaggcgatatggtcagtgaagaagatccgctgatcgaactggaatccgacaag
gccacgatggaagtgccttcgcccgcagcgggcaaggtcacggaaatcaaggtcaaggaa
ggggatcgcattggcgagggggcggtgatccttgtcctcgaaggcgcggatgccaaggat
gaggcccccaaggccgaagcccctgccgccgaggcgcctaaacaggtctccgccaccggc
acggcctctggtcctggtgatgtgcatgccgaggtcgttgttctgggctctggccccggc
ggctatacggcggcgttccgcgccgccgatctgggcaagaaaaccgtcctgattgagaaa
ttcgaccgattgggcggtgtctgtctgaacgtcggctgtatcccgtccaaggcactgctg
cacgtcgccaaggtcatcaccgaggctgaggagatgggcgcgcatggcatcagcttttcc
aagccgggaatcgatctggatgagctgcgtgccttcaaggacagcgttgtcggcaagctg
accggcggtctggacggattgtccaagggccgcaaggtgcaggtggtgcgcggttatggc
aaattctcgggcccgaacatgatcgaggttcagggcgacgatggcgtgaccaccgtgtcc
tttgaccagtgcatcatcgccgccgggtccgagcccgtggcgctgcctttcatcccgcat
gacgatccgcgcgtgatcgacagcaccggcgcgctggaactggcggacatccccggacgg
atgctggttctgggcggtggcatcatcgggctggaaatggcttgtgtctacgacgcgctg
ggatcgaagatcacagtcgtcgaactgatggaccagatcattccgggggccgacaaggac
atcgtcaagccgctgatgacccgcatcaagggtcggtatgagaacatcttcctcaagacc
aaggtgacagcggtcgaagcgttggacgagggtatgaaagtgaccttcgaggacgacaag
ggcgagagcttctctgacaccttcgataaggttcttgtcgccgtgggtcgcaagcccaac
ggcaaactgatcgatgccgacaaagccggcgttgccgttgacgaccgtggctttatcgcc
gtggacaagcagcagcgcacgggcgtgccgcatatcttcgccatcggcgacgtagtgggc
cagccgatgctggcccacaaggccgtgcacgagggcaaggtggcagccgaggtttgcgcc
ggacacaagcgattctttgacgcccagttgatcccttcggttgcctataccgatccagag
gtcgcttggtgtggtgtcaccgaaaacgacgccaaggcgaagggcatcaagtacgagaag
ggcgtgttcccttgggcagcttcgggcaaatcgctatcgaatggccgtagtgaggggatc
accaagctgctgttcaatcccgacgatgaccgcatcatcggtgcgtgtatcgtgggcacc
aacgcgggcgacctgatttccgaggccgctctggccatcgaaatgggcgcagatgccgtg
gatcttggccacacaatccacccgcacccgacgctgtcggaaacggtgaactttgcggcc
gagatgttcgagggcacaattaccgacctgatgccgccgaaaaagcgcaagcactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (23)   
   KEGG PATHWAY (16)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (17)   
   Pfam (17)   
All databases (100)   

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