KEGG   Actinosynnema mirum: Amir_4588
Entry
Amir_4588         CDS       T00957                                 
Name
(GenBank) amino acid adenylation domain protein
  KO
K19103  nocardicin nonribosomal peptide synthetase NocB
Organism
ami  Actinosynnema mirum
Pathway
ami00261  Monobactam biosynthesis
ami01100  Metabolic pathways
ami01110  Biosynthesis of secondary metabolites
Module
ami_M00736  Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
Brite
KEGG Orthology (KO) [BR:ami00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    Amir_4588
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:ami01008]
    Amir_4588
Polyketide biosynthesis proteins [BR:ami01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   Nocardicin synthetase
    Amir_4588
SSDB
Motif
Pfam: AMP-binding Condensation PP-binding Thioesterase AMP-binding_C Abhydrolase_1
Other DBs
NCBI-ProteinID: ACU38421
UniProt: C6WLM8
Position
complement(5436139..5441916)
AA seq 1925 aa
MTFRVRDLFADDAGEATAQLAAWNDTARDFPTEVGVHELVRRQAAEHGARGAVTFEGATT
TYAELDAAAAGLARRLAGAGVRPGDVVAIALPPSERRIAAVLGALRAGAAYLPLDPELPA
PRLEFLLADAGAAVLITDTATREGPVAAHDGPTVLCDRLSPDGAPTAEPTAEPAEFPGSA
LAAYVIYTSGSTGRPKGVAVDHRSLVNRLLWMRERYGVGQGDVVLHKTSFGFDVSVWEQL
LPLISGARLVIAPQETRRDATALVRLVRAESVTVLHFVPSLLPAFLDVAEVEQARALRVA
ISSGEALPKPVAVDFARRLPHCALHNLYGPTEATIDVTHWPVDGDDERPFVPIGTPIDNT
SVYVLDDHLEPLPVGAEGELCIGGQAVALGYLGRPALTAEKFAPDPFGAPGARMYRTGDR
ARFGPDGAIEYLGRRDGQVKLRGYRVELGETEAALLESDLVRQAAVVVRGEGGAKRLVGF
VSGRPEAAGGAEGAEAHVLARLSATLPAYQVPSQLVWLDALPLTPSGKVDRAALPETAAA
HRSSAAPETPTERAIAALWAELLDGPEPGLDDDFFRTGGDSVSSMRLAARAQRQGVRLDV
QHIFTHRTVRGMAAAADEASTRPVVAEPRGDDEEALLAGVDPEHLAQVRARPGVVDVYPL
APMQEGMLFRGLFWPDSDAYFNQNVLELVGGTDEDVLREAWRRVADRYEILRTGFTWRDR
AEPLQYVRDDLAPPWALLDWSGEDPDRRAELLERLLADDRAAGLSLADCPLYRLTLVRLG
GGRHYLLWSHHHILLDGWCLSLIWGDVFRVYEELAHGREPRLEPVRPYRDYVRWIRARAA
RSEESERFWREYLRDLTPSPFSTAPADREGEFDTVVHEFPEQLTRLVNEAARGYGVTTNA
ISQAAWSMLLALQTGARDVVHGLTIAGRPPELEGSEHMVGIFINTIPLRIRLDPDQTVTG
LLETIHRDLATTAAHGHVPLAQIKSWASGERLSGGRVFDNLVAFENYPEDNLPGDDLSIQ
IIDLHAQEKTEYPIGLIVLPLQKLAFHFNYDTTHFTRAQVDRFIEVFRLLTEQLCRRPSA
RLSELELLPAADRELLGSWNGATRGTTGDGQEPSLLDLFLRHRAATPDAPAVVENGVVLD
YAGLDERAIALAGRLAEAGVRAGHLVGVCLRRSAAHPIALLAVYRSGAVPVLLDPEHPVA
RLREAAADAGVAAVVTTADQAGFEAWPVVHPDGGIVAPTEPAACRPGSADPARDACVVYT
SGSTGGPKGVLAPQAGLVNRVLWSGRAFPTPEPPRVLATAGTAFDIALWELFFPLAHGGA
VVTAPQDAVLDPDALAELIVAERVTVAHFLPSLLAAFLDSPKAAGCTGLAHVLSGGEAVT
PAIVRAFTGSGLPARLHQAYGPAEASISVTHHTCAPEDGLRERVPIGRPIDGAGAHVVDE
HLRELPVGCVGELAVTGVAVGAGYPNDPELTARRFPANPFGAQPLYLTGDLARWGADGEL
EFLGRRDRQVKVRGHRVEPAEVDRTAELHPGVRQAVTVFRDGALTTFAAPRAGALLDVAD
LRRLLRERLPDWMVGELVVLDALPVTGNGKVDQRALLDLAGAGTRSAVVGSRPPATELEK
LVARCWEEVLGVTGIGAHDDFFEIGGHSLLVVRLLRVLRDNLPEGVHCDVPHILKAPTVA
GLAEQLLAPVEGSGSAYVHTLNPEATGGALVLVHPGEGLALPYHGLAPLLPDVRLHVLSD
PRFGQSDNRFATLAEMATRYVEWVRTTEPEGPYRLGGWSFGGVVALEMASQMTAHGDEVS
DLLLVDSHNLNAAPRTGDPREGVRQRLVELGVDPDSPEGVDVVEELLHNGALAAQYAPPA
YRGRVSLLVTPTDGDRDAVRARGWDRALLPDLVVEPVPGAHERLFDEEHLSDTADAIRRA
LGGER
NT seq 5778 nt   +upstreamnt  +downstreamnt
gtgacctttcgagtgcgcgacctgttcgccgacgacgcaggcgaggccaccgctcagctg
gccgcgtggaacgacaccgcccgcgacttccccaccgaggtgggcgtgcacgagctcgtg
cggcggcaggccgccgagcacggcgcgcgcggcgcggtgaccttcgagggcgcgaccacg
acctacgcggagctggacgccgcggcggccgggctggcgcggcggctggcgggcgcgggc
gtgcggcccggtgacgtcgtggccatcgcgctgcccccgtcggagcggcggatcgccgcc
gtcctcggcgcgctgcgcgcgggcgccgcgtacctgccgctggaccccgagctgcccgcg
ccgaggctggagttcctgctcgccgacgccggggccgcggtgctgatcaccgacacggcc
acgcgggagggcccggtcgccgcccacgacgggccgaccgtgctgtgcgaccggttgtcc
ccggacggtgctcccaccgccgagcccaccgccgagcccgcggagttccccggctccgcg
ctggcggcctacgtcatctacacctcgggctccaccggccgccccaagggcgtcgcggtc
gaccaccgcagcctggtcaaccgcctgctgtggatgcgcgagcggtacggggtcgggcag
ggcgacgtggtcctgcacaagacgtccttcggcttcgacgtctccgtgtgggagcagctg
ctgccgctgatcagcggcgcccgcctggtgatcgccccgcaggagacccggcgagacgcc
accgcgctggtccggctcgtgcgcgccgagtcggtgacggtgctgcacttcgtgccctcg
ctgctgcccgcgttcctcgacgtcgcggaggtcgagcaggcccgcgcgctgcgggtggcg
atctccagcggcgaggcgctgcccaagccggtggccgtcgacttcgcccggcgcctgccg
cactgcgcgctgcacaacctctacgggccgaccgaggccaccatcgacgtcacgcactgg
ccggtcgacggcgacgacgagcgccccttcgtgcccatcggcaccccgatcgacaacacc
agcgtctacgtgctcgacgaccacctggaaccgctgccggtcggcgcggagggcgagctg
tgcatcggcgggcaggcggtggcgctgggctacctcgggcggcccgcgctcaccgccgag
aagttcgcgcccgacccgttcggcgcccccggcgcgcgcatgtaccgcaccggcgaccgg
gcccggttcggccccgacggcgcgatcgagtacctggggcggcgcgacgggcaggtcaag
ctgcgcggctaccgcgtcgagctgggcgagaccgaggccgcgctgctggagtccgacctc
gtccggcaggcggccgtggtggtgcgcggcgagggcggggccaagcggctggtgggcttc
gtctccggccgcccggaggccgcgggcggcgccgagggcgcggaggcgcacgtgctggcg
cgcctgtccgcgaccctgcccgcctaccaggtgccgtcgcagctggtgtggctcgacgcc
ctgccgctgaccccctccggcaaggtggaccgcgcggcgctgcccgagaccgcggcggcc
caccggtcgtccgccgcgcccgagacccccaccgagcgggcgatcgcggcgctgtgggcg
gagctgctggacggccccgaaccgggcctggacgacgacttcttccgcaccggcggcgac
tcggtgtccagcatgaggctggccgcgcgggcccagcgccaaggcgtccggctcgacgtg
cagcacatcttcacccaccgcacggtccggggcatggccgccgccgccgacgaggcgtcc
acccgcccggtcgtggccgagccgcgcggcgacgacgaggaggcgctgctggcgggtgtc
gaccccgagcacctggcgcaggtgcgcgcgcgccccggcgtcgtggacgtctaccccctc
gccccgatgcaggaggggatgctcttccgcggcctgttctggcccgactcggacgcctac
ttcaaccagaacgtgctggagctggtcggcgggaccgacgaggacgtgctgcgcgaggcg
tggcggcgggtcgccgaccgctacgagatcctgcgcaccggcttcacctggcgcgaccgg
gccgagccgctccagtacgtgcgcgacgacctcgcgccgccgtgggcgctgctcgactgg
tccggcgaggaccccgatcgccgcgcggagctgctggagcggctgctggccgacgaccgg
gccgccgggctctcgctggccgactgcccgctgtaccggctgaccctggtgcggctcggc
ggcggacggcactacctgctgtggagccaccaccacatcctgctcgacggctggtgcctg
tccctgatctggggcgacgtgttccgggtctacgaggagctggcgcacggccgcgagccg
cggctggaaccggtccgcccctaccgggactacgtgcgctggatcagggccagggccgcg
cgcagcgaggagtccgagcggttctggcgcgagtacctgcgggacctgacccccagcccg
ttctcgaccgcccccgccgaccgggagggcgagttcgacaccgtcgtccacgagttcccc
gagcagctcacgcggctggtgaacgaggcggcgcgcgggtacggcgtcaccaccaacgcg
atcagccaggcggcgtggagcatgctgctcgcgctccagaccggcgcgcgcgacgtggtg
cacggcctgaccatcgcgggccgcccgcccgagctggagggctcggagcacatggtgggc
atcttcatcaacaccatcccgctgcggatcaggctcgaccccgaccagacggtgaccggg
ctgctggagaccatccaccgcgacctggccaccacggcggcccacggccacgtcccgctg
gcccagatcaagtcgtgggcctccggcgagcggctgtccggcggccgggtcttcgacaac
ctggtggccttcgagaactaccccgaggacaacctgcccggcgacgacctgagcatccag
atcatcgacctgcacgcgcaggagaagaccgagtacccgatcggtctcatcgtgctgccg
ctgcagaagctcgcgttccacttcaactacgacaccacgcacttcacccgcgcccaggtg
gaccggttcatcgaggtcttccggctgctcaccgagcagctgtgccgccgcccctcggcg
cggctgagcgagctggagctgctgcccgccgcggaccgcgagctgctcgggagctggaac
ggcgcgacccgcggcacgaccggcgacgggcaggagccgtccctgctcgacctgttcctc
cgccaccgggcggccacgccggacgcgcccgccgtggtggagaacggggtcgtgctcgac
tacgccgggcttgacgagcgcgcgatcgcgctggcgggccggctggccgaggcgggcgtg
cgcgccgggcacctggtgggcgtctgcctgcggcgctccgcggcccacccgatcgcgctg
ctggccgtttaccgcagcggcgcggtgccggtgctgctcgaccccgagcacccggtggcg
cggctgcgggaggcggcggcggacgcgggcgtggccgccgtggtgacgacggcggaccag
gccgggttcgaggcgtggccggtcgtccaccccgacggggggatcgtcgcgccgacggag
cccgccgcctgccgacccggctcggccgacccggcccgcgacgcctgcgtcgtctacacc
tcgggctcgaccggcgggcccaagggcgtgctcgcgccccaggcggggctggtgaaccgg
gtgctgtggtcgggtcgcgcgttccccaccccggaaccgccgcgcgtgctggccaccgcg
ggcaccgcgttcgacatcgcgctgtgggagctgttcttcccgctggcgcacgggggagcg
gtggtgaccgcgccccaggacgccgtgctcgacccggacgcgctggccgagctgatcgtc
gcggagcgggtgaccgtggcgcacttcctgcccagcctgctcgccgcgttcctggacagc
cccaaggccgccggctgcaccgggctggcgcacgtcctgtccggcggcgaggccgtcacc
cccgcgatcgtccgcgccttcaccggctccggcctgcccgcccggctgcaccaggcgtac
ggcccggccgaggcctcgatcagcgtcacccaccacacctgcgccccggaggacggcctg
cgcgagcgcgtgccgatcggcaggcccatcgacggcgccggggcgcacgtcgtggacgag
cacctgcgcgagctgcccgtcggttgcgtcggcgagctggccgtcaccggcgtcgcggtc
ggggcgggctacccgaacgacccggagctgaccgcgcggcggttccctgccaaccccttc
ggcgcgcagccgctctacctcaccggcgacctggcccgctggggcgccgacggcgagctg
gagttcctcggcaggcgcgaccggcaggtgaaggtgcgcgggcaccgggtcgagcccgcc
gaggtggaccgcaccgccgagctgcaccccggggtgcgccaggcggtcaccgtcttccgc
gacggcgcgctgaccacgttcgcggcgccgcgcgcgggcgccctgctcgacgtggccgac
ctgcgccgcctgctgcgcgagcggctgccggactggatggtcggcgagctggtggtgctc
gacgcgctgccggtgaccggcaacggcaaggtggaccagcgcgcgctgctcgacctggcg
ggcgccgggacccggtcggcggtcgtgggctcgcgcccgcccgccaccgagctggagaag
ctcgtcgcgcgctgctgggaggaggtgctgggcgtcacgggcatcggcgcgcacgacgac
ttcttcgagatcggcggccactccctgctggtggtgcggctgctccgggtcctgcgggac
aacctgccggaaggggtgcactgcgacgtgccgcacatcctcaaggcgcccaccgtcgcc
gggctcgccgagcagctgctcgcccccgtcgagggctccgggtcggcctacgtgcacacc
ctcaacccggaggcgaccggcggcgcgctggtcctcgtgcaccccggcgaggggctggcg
ctgccctaccacgggctggcgccgctgctgcccgacgtgcgcctgcacgtcctctccgac
ccgcgcttcgggcagtcggacaaccggttcgccaccctggccgagatggccacccgctac
gtcgagtgggtgcgcaccaccgagcccgaggggccgtaccgcctcggcggctggtccttc
ggcggcgtggtggcgctggagatggccagtcagatgaccgcgcacggcgacgaggtgtcg
gacctgctgctcgtcgacagccacaacctcaacgccgcgccccgcaccggggacccccgc
gagggcgtgcggcagcggctggtcgagctgggcgtcgacccggactccccggagggcgtg
gacgtcgtggaggagctgctgcacaacggcgccctcgccgcgcagtacgcgcccccggcc
taccggggccgggtgagcctgctggtgacccccaccgacggcgaccgcgacgccgtgcgc
gcgcggggctgggaccgggcgctgctgccggacctggtcgtcgaacccgtgccgggcgcg
cacgagcggttgttcgacgaggagcacctgtccgacacggcggacgcgatccgccgcgcg
ctgggaggagagcggtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (55)   

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