KEGG   Ailuropoda melanoleuca (giant panda): 100465351
Entry
100465351         CDS       T01329                                 
Symbol
PIK3C3
Name
(RefSeq) phosphatidylinositol 3-kinase catalytic subunit type 3
  KO
K00914  phosphatidylinositol 3-kinase [EC:2.7.1.137]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00562  Inositol phosphate metabolism
aml01100  Metabolic pathways
aml04070  Phosphatidylinositol signaling system
aml04136  Autophagy - other
aml04140  Autophagy - animal
aml04145  Phagosome
aml04371  Apelin signaling pathway
aml05010  Alzheimer disease
aml05014  Amyotrophic lateral sclerosis
aml05016  Huntington disease
aml05017  Spinocerebellar ataxia
aml05022  Pathways of neurodegeneration - multiple diseases
aml05132  Salmonella infection
aml05152  Tuberculosis
aml05167  Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100465351 (PIK3C3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    100465351 (PIK3C3)
   04070 Phosphatidylinositol signaling system
    100465351 (PIK3C3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100465351 (PIK3C3)
   04140 Autophagy - animal
    100465351 (PIK3C3)
   04136 Autophagy - other
    100465351 (PIK3C3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    100465351 (PIK3C3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100465351 (PIK3C3)
   05152 Tuberculosis
    100465351 (PIK3C3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100465351 (PIK3C3)
   05014 Amyotrophic lateral sclerosis
    100465351 (PIK3C3)
   05016 Huntington disease
    100465351 (PIK3C3)
   05017 Spinocerebellar ataxia
    100465351 (PIK3C3)
   05022 Pathways of neurodegeneration - multiple diseases
    100465351 (PIK3C3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aml04131]
    100465351 (PIK3C3)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.137  phosphatidylinositol 3-kinase
     100465351 (PIK3C3)
Membrane trafficking [BR:aml04131]
 Endocytosis
  Macropinocytosis
   Kinases
    100465351 (PIK3C3)
  Rab GTPases and associated proteins
   Rab associated proteins
    100465351 (PIK3C3)
 Endosome - Lysosome transport
    100465351 (PIK3C3)
 Autophagy
  Autophagosome formation proteins
   PI3K complex
    100465351 (PIK3C3)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_C2 HEAT_2
Other DBs
NCBI-GeneID: 100465351
NCBI-ProteinID: XP_034498094
Ensembl: ENSAMEG00000007466
Position
14:75721806..75858175
AA seq 901 aa
MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVT
CQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAV
PVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKGES
TSQKIDGEGETGLKRMLFHISPYARNEKQIVMSIIEMINESEKRSSNFMYLMVEFRCVKC
DDKEYGIVYYEKDGDESSPILTSFEIVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDL
KPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAK
QALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYE
NFEDIKNGLEPTKKDSQGSVSESVSNSGINSAEIDSSQIITSPLPPVSSPPPAAKTKDSS
DGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQ
ALLKGDKCVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLS
DVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQL
ILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRK
YAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYIL
GRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDA
NIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWR
K
NT seq 2706 nt   +upstreamnt  +downstreamnt
atgggggaagcggagaaatttcactacatctacagctgtgacctggacatcaacgtgcag
cttaagataggaagtttggaagggaagagagaacagaagagttataaagctgttctagaa
gacccaatgttgaagttttcaggactgtaccaagagacatgctctgacctttatgttact
tgtcaagtttttgcagaagggaagcctctggctttgccagtgagaacatcctacaaagca
tttagtacgagatggaactggaatgaatggctgaaactgccagttaagtaccctgacctg
cccaggaatgcccaggtggccctcacaatatgggatgtgtatggaccaggaaaggcagtg
cctgtgggaggaacaacggtttcactctttggaaaatacggtatgtttcgccaagggatg
cacgacttgaaagtctggcctaatgtagaagcagatggatcagaacccacaaaaactcct
ggcagaacaagcagtactctctcagaagatcagatgagccgccttgccaagggtgagagc
acgagccagaagatagacggagagggagaaacagggctgaaacgaatgctgtttcatatt
tcaccttatgcccgcaatgaaaaacaaatagtaatgagtataatagaaatgataaatgag
agtgagaaacgaagttctaatttcatgtacttgatggttgagtttcggtgtgtcaagtgt
gatgataaggaatatggtattgtttattatgaaaaggatggtgatgagtcatctccaatt
ttaacaagctttgagatagtaaaagttcctgaccctcagatgtctatggagaatttagtt
gagagcaaacaccacaagcttgcccggagtttaagaagtggaccttctgaccatgatctc
aaacctaacgctgccacaagagatcagctaaatattattgtgagttatccaccaaccaag
caacttacatatgaagaacaagatcttgtttggaagtttagatattatcttactaatcaa
gaaaaagccttgacaaagttcttgaaatgtgttaattgggatctacctcaggaggccaaa
caggcattggaacttctaggaaaatggaagccaatggatgtagaggactccttggagctg
ttatcctcccattacaccaatccaacagtcaggcgttatgctgttgcccggttgcgacag
gcagatgatgaggatttgttgatgtacctattacagctggtccaagctctcaaatacgaa
aattttgaagacataaagaatggattagaacctaccaagaaggatagtcagggttcagtg
tcagagagtgtgtcaaattctggaataaattctgcagaaatagatagctcccaaattata
accagcccgcttcctccagtgtcttcccctcctcctgcagctaaaacaaaagacagttca
gatggtgaaaatctagagcaagatctctgcaccttcttgatatcaagagcctgcaaaaac
tcaacactggctaattatttatactggtatgtgatagtggaatgtgaagatcaagacact
cagcaaagagacccaaagacccatgagatgtacttgaatgtaatgagacgattcagccaa
gcattgttgaagggtgataagtgtgtcagagttatgcgttctttgctggctgcacagcag
acgtttgtagatcggctggtgcatctaatgaaggcagtgcagcgtgaaagcggaaatcgt
aagaaaaagaacgagagactacaggcattgcttggagacaatgaaaagatgaacttgtca
gatgtggaacttatcccattgcctttagaaccccaggtgaaaattagaggaataatccca
gaaacagctacactatttaagagtgctcttatgcctgcacagttattctttaagacagaa
gatggaggcaaatacccagttatatttaagcatggagatgatttacgccaagatcaactt
attcttcaaatcatttcactcatggacaagctgctacggaaggaaaatctggatttgaag
ttgacaccctacaaggtattagccaccagtacaaaacatggcttcatgcagtttatccag
tcagttcctgttgctgaagttcttgatacagagggaagcattcagaacttctttagaaag
tacgcaccaagtgaaaatgggccaaatgggatcagtgctgaagttatggacacctatgtt
aaaagctgtgctggatattgtgtgattacatacatacttggagttggagacagacacctg
gataaccttttgctaacaaaaacaggcaaactcttccacatagacttcggatatattttg
ggtcgggatccgaagcctcttcctcctccaatgaagctgaataaagaaatggtagaagga
atggggggcacccagagtgagcagtaccaagagttccgtaaacagtgttacacggctttt
ctccaccttcgaaggtattctaaccttattttgaacttgttttccctgatggtggatgca
aacattccagatattgctcttgaaccagataaaactgtgaaaaaggttcaggataaattc
cgactcgacctatctgatgaagaggcggtgcattacatgcagagtctgatcgacgaaagt
gtccatgctctctttgctgcagtggtagagcagattcacaagtttgcccagtactggaga
aaatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (15)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (45)   

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