KEGG   Ailuropoda melanoleuca (giant panda): 100468267
Entry
100468267         CDS       T01329                                 
Symbol
FGFR2
Name
(RefSeq) fibroblast growth factor receptor 2
  KO
K05093  fibroblast growth factor receptor 2 [EC:2.7.10.1]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml01521  EGFR tyrosine kinase inhibitor resistance
aml04010  MAPK signaling pathway
aml04014  Ras signaling pathway
aml04015  Rap1 signaling pathway
aml04020  Calcium signaling pathway
aml04144  Endocytosis
aml04151  PI3K-Akt signaling pathway
aml04550  Signaling pathways regulating pluripotency of stem cells
aml04810  Regulation of actin cytoskeleton
aml05200  Pathways in cancer
aml05215  Prostate cancer
aml05226  Gastric cancer
aml05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100468267 (FGFR2)
   04014 Ras signaling pathway
    100468267 (FGFR2)
   04015 Rap1 signaling pathway
    100468267 (FGFR2)
   04020 Calcium signaling pathway
    100468267 (FGFR2)
   04151 PI3K-Akt signaling pathway
    100468267 (FGFR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100468267 (FGFR2)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100468267 (FGFR2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100468267 (FGFR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100468267 (FGFR2)
   05230 Central carbon metabolism in cancer
    100468267 (FGFR2)
  09162 Cancer: specific types
   05226 Gastric cancer
    100468267 (FGFR2)
   05215 Prostate cancer
    100468267 (FGFR2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100468267 (FGFR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100468267 (FGFR2)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:aml04090]
    100468267 (FGFR2)
   00536 Glycosaminoglycan binding proteins [BR:aml00536]
    100468267 (FGFR2)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100468267 (FGFR2)
Protein kinases [BR:aml01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   100468267 (FGFR2)
CD molecules [BR:aml04090]
 Proteins
  100468267 (FGFR2)
Glycosaminoglycan binding proteins [BR:aml00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100468267 (FGFR2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set Ig_5 C2-set_2 ABC1 V-set_CD47 Pkinase_fungal Kinase-like SMP_2
Other DBs
NCBI-GeneID: 100468267
NCBI-ProteinID: XP_034519520
Ensembl: ENSAMEG00000010959
Position
6:complement(119838293..119940655)
AA seq 834 aa
MGVTSTWRYGRGRGIGTAAAMVSWARFVCLVVVTMATLSLARPSFNLVEDTTLEPEEPPT
KYQISQPEVYVAAPGESLELRCLLRDAATISWTKDGVHLGPNNRTVLIGEYLQIKGATPR
DSGLYACTAARPVDSEAVYFMVNVTDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKV
YSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDREIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRM
KTTTKKPDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAG
VSEYELPEDPKWEFPRDKPKELHRYRPVKRVNGAPAADGGEKTNWFLIYLMFVDDATEKD
LSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYS
YDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGL
ARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI
PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNE
EYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHVNGSVKT
NT seq 2505 nt   +upstreamnt  +downstreamnt
atgggagtgacgtccacgtggagatatggaagaggacgggggattggcaccgccgcagcc
atggtcagctgggcccgcttcgtctgcctggtcgtggtcaccatggcaaccttgtccctg
gcccggccctccttcaatttagtggaggataccactttagagccggaggagccgccaacc
aaataccaaatctcccaacctgaagtttacgtggccgcgcccggggagtcgctagagttg
cgctgtctgttgagagatgccgccacgatcagttggactaaggatggggtacacttgggg
cccaacaataggacagtgcttattggggaatacttgcagataaaaggtgccacgcctaga
gactccggcctctatgcttgcacggcggctaggccggtagacagcgaggctgtctacttc
atggtgaatgtcacagatgccatctcatccggagatgacgaggacgacacagatggctcc
gaggattttgtcagtgagaacagtaacaacaagagagcgccgtactggaccaacacagaa
aagatggaaaagcgacttcatgctgtccctgcagccaatactgtcaagtttcgctgccca
gctggggggaatccaacaccaactatgcgatggctgaagaatggaaaggagtttaagcag
gaacatcgcattggaggctataaggtgcgaaaccagcattggagccttattatggagagc
gtggtcccgtccgacaaaggaaattacacctgtgtggtagagaacgagtacggctccatc
aatcacacgtaccacctcgatgtcgttgagcgatcgccacaccggcccatcctccaagcg
ggactgccggccaatgcttccaccgtggtcgggggcgacgtggagttcgtctgcaaagtg
tacagcgatgcccagccccacattcagtggatcaaacatgtagaaaagaacggcagcaaa
tacgggcccgacgggctgccttacctcaaggtgctgaaggccgccggtgttaataccacg
gacagagagattgaggttctctatattcggaatgtaacttttgaggatgctggggaatat
acgtgcttggcgggtaattctattgggatatcctttcactctgcatggttgacagtcctg
ccagctcctgtaagagaaaaggagattacggcttccccagactacctggagatagccatt
tactgcataggggtcttcctgattgcctgtatggtggtgacggtcatcctgtgccgaatg
aagaccacgaccaagaagccagacttcagcagccagccagctgtgcacaagctgaccaag
cgcatccccttgcggagacaggtttctgccgagtccagttcctccatgaactccaacacc
ccgctggtcaggataaccacgcgcctctcctcaacggcagacacccccatgctggcaggg
gtctccgagtatgaattgccagaagatccaaagtgggagttcccaagagataagcccaaa
gaactgcacaggtatcgccctgtcaagagagttaatggcgcaccagccgccgatggggga
gagaaaactaactggtttttaatttacctaatgtttgtagatgatgccaccgagaaggat
ctttctgatctggtgtcagagatggagatgatgaagatgattggaaaacacaaaaatatc
ataaatctccttggagcctgtactcaggatgggcctctctacgtcatcgtggagtatgcc
tcgaaaggcaacctccgcgaatacctccgagcgcgcaggccgccggggatggagtactcc
tatgacattaaccgcgttcccgaggagcagatgaccttcaaggacttggtgtcttgcacc
taccagctggcaagaggcatggagtacttggcttcccagaaatgtattcatcgggattta
gcagccagaaatgttttggtcacagaaaacaatgtcatgaaaatagcagactttggactg
gccagggatatcaacaatatagattattacaaaaagaccacaaacgggcgacttccagtc
aagtggatggccccagaagccctttttgaccgggtgtacacccatcagagtgacgtgtgg
tccttcggggtgttaatgtgggagatcttcacgttagggggctccccctacccagggatt
ccggtggaggaactttttaagctgcttaaggaaggacacaggatggataagccggccaac
tgcaccaatgagctgtatatgatgatgagggactgctggcatgcggtgccctcccagagg
ccgacgttcaaacagctggtagaagacttggaccggattctcactctcacaaccaatgag
gaatacttggacctcagtcagcctctcgaacagtattcacctagttatcctgacacaagg
agttcttgttcttcaggagacgattctgttttctctccggaccccatgccttacgaaccc
tgccttcctcagtatccacatgtgaacggcagtgttaaaacatga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (13)   
   KEGG PATHWAY (13)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (45)   

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