KEGG   Ailuropoda melanoleuca (giant panda): 100479165
Entry
100479165         CDS       T01329                                 
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00230  Purine metabolism
aml00670  One carbon pool by folate
aml01100  Metabolic pathways
aml01523  Antifolate resistance
Module
aml_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100479165 (GART)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100479165 (GART)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100479165 (GART)
Enzymes [BR:aml01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     100479165 (GART)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     100479165 (GART)
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     100479165 (GART)
SSDB
Motif
Pfam: GARS_A Formyl_trans_N AIRS_C GARS_N GARS_C AIRS ATP-grasp ATP-grasp_2 ATP-grasp_3 ATP-grasp_4 CPSase_L_D2 Dala_Dala_lig_C RimK
Other DBs
NCBI-GeneID: 100479165
NCBI-ProteinID: XP_002919622
Ensembl: ENSAMEG00000014882
UniProt: D2HCF9
Position
1:10911333..10941023
AA seq 1010 aa
MAARVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACLEKISNTAISINDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKPEEACSFIMSSDFPALVVKASGLAAGKGVIVAKSTEEACRAVQEIMQDKAY
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENRTAITVVMASKGYPGNYTKGVEITGFPEA
QALGLEVFHAGTVLKDGKVVTNGGRVLTVTAIRENLTVALEEAKKGLAAIKFEGAIYRKD
IGYRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIARACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPEGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLTEQILRDIKQHKEEAWVIGKVVACPEGSPRVKVKN
LIETMQINRSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEYSTEIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDTVATLSERVKLAEHRIFPAALQLVASGAVQLGQDGKIRWVTEE
NT seq 3033 nt   +upstreamnt  +downstreamnt
atggcagcccgagtacttgtaattggcagtggaggaagggaacacacactggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgctccaggaaatgcaggcactgcc
tgcttggaaaagatttcaaatactgccatctcgatcaatgaccacactgcccttgctcaa
ttctgcaaagatgagaaaattgaattcgtagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtgcaatgctttggtcccactgcagaagca
gctcagttagagtccagcaagagattcgccaaagagtttatggaccgacatggaatccca
actgcacggtggagagctttcaccaaacctgaagaagcctgcagctttataatgagttca
gacttccctgctttggttgtgaaggccagtggtcttgcggctggaaaaggggtgattgtt
gccaagagcacagaagaggcctgcagggctgtacaggagatcatgcaggataaagcttat
ggagcagctggagaaacaattgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggacggtggctcctatgcccccagcacaagaccataagcga
ctgctggagggagatcacggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttactgaaaataaaaaataccattcttcaaaggacagtggat
ggcatgcagcaggagggaatgccgtacacaggtgttctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaactgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttggatggcctg
ctctgcacatctctgcctgtttggcttgaaaaccgcactgccataactgttgtgatggca
agtaaaggctatccaggaaattataccaagggtgtggagataacagggtttcctgaggct
caggctttaggactggaggtgttccacgcaggcactgtgctgaaagatggcaaagtggtg
actaatgggggtagagtccttacagtaacagccatccgggaaaatcttaccgtggccctt
gaagaagccaagaaaggactagctgctataaaatttgagggagccatttataggaaggac
attggctatcgtgccatagcttttctccagcagcccaggggcctgacttataaggaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaaacctttagcaaaagct
acctccagaccaggctgcgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcaagtggaacagatggtgttggaactaaactg
aagattgcccagcagtgtaataaacatgataccattggtcaagatttggttgcaatgtgt
gtcaatgacattctggcccaaggggcagagccccttttcttcctcgattacttttcctgt
ggaaaacttgacctgaatacaactgaagctgttgtcgctggaatcgccagagcttgtgga
aaagctggatgtgctctccttggaggtgaaactgcagagatgccggacatgtatcctccg
ggagaatatgacctagccggttttgctgttggtgccatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggatgttgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtaaggaaaattgtagcaaaatcttctctccagtactcgtct
ccagcacctgaaggctgtggtgaccagaccttaggggacttacttctcactcctaccaga
atttacagccattcactgctacctgtgctacgttcaggacatgtcaaggcctttgcccat
attactggtggaggattgctagaaaacattcccagagtccttcctcagaagtttggggtg
gatttagatgcccagacctggagggtccccaggatcttctcgtggttacagcaggaagga
cacctctctgaggaagagatggccagaacatttaactgtggaattggggctgccctcgtg
gtatcaaaagatctgacagagcagattctgagggatattaaacagcacaaggaagaagcc
tgggtgattggcaaggtggttgcatgtcctgaaggttctcctcgtgtgaaagtcaagaat
ctgatagaaaccatgcaaataaatagatcagtattggagaatggcaccctgaaaaatcat
ttctctgtccaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctacaagctctcatagacagtactagggagccgagtagctgtgcacacattgttgttgtt
atctccaacaaagccgcagtggctggcttagataaagcggaaagagctggaattcccacc
agagtaattaatcataaattatataaaagtcgtgtagaatttgacactgccattgaccaa
gtccttgaagagtactccacagagatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcaggaaatgggatgggaagatgctcaatatccacccatccttgctccct
tcttttaagggttcaaatgcccacgagcaagccctagaagctggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaatct
gttccagtgaagagaggtgacactgttgcaactctgtctgaaagagtgaaattagcagag
cacagaatatttcccgcagccctccagctggtagccagtggagctgtacaacttggacaa
gatggcaagattcgttgggtcacagaggagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (13)   
   Pfam (13)   
All databases (61)   

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