KEGG   Ailuropoda melanoleuca (giant panda): 100481376
Entry
100481376         CDS       T01329                                 
Symbol
PRKAA2
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1
  KO
K07198  5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04068  FoxO signaling pathway
aml04140  Autophagy - animal
aml04150  mTOR signaling pathway
aml04151  PI3K-Akt signaling pathway
aml04152  AMPK signaling pathway
aml04211  Longevity regulating pathway
aml04213  Longevity regulating pathway - multiple species
aml04371  Apelin signaling pathway
aml04530  Tight junction
aml04710  Circadian rhythm
aml04714  Thermogenesis
aml04910  Insulin signaling pathway
aml04920  Adipocytokine signaling pathway
aml04921  Oxytocin signaling pathway
aml04922  Glucagon signaling pathway
aml04931  Insulin resistance
aml04932  Non-alcoholic fatty liver disease
aml04936  Alcoholic liver disease
aml05410  Hypertrophic cardiomyopathy
aml05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    100481376 (PRKAA2)
   04068 FoxO signaling pathway
    100481376 (PRKAA2)
   04151 PI3K-Akt signaling pathway
    100481376 (PRKAA2)
   04152 AMPK signaling pathway
    100481376 (PRKAA2)
   04150 mTOR signaling pathway
    100481376 (PRKAA2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100481376 (PRKAA2)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100481376 (PRKAA2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100481376 (PRKAA2)
   04922 Glucagon signaling pathway
    100481376 (PRKAA2)
   04920 Adipocytokine signaling pathway
    100481376 (PRKAA2)
   04921 Oxytocin signaling pathway
    100481376 (PRKAA2)
  09149 Aging
   04211 Longevity regulating pathway
    100481376 (PRKAA2)
   04213 Longevity regulating pathway - multiple species
    100481376 (PRKAA2)
  09159 Environmental adaptation
   04710 Circadian rhythm
    100481376 (PRKAA2)
   04714 Thermogenesis
    100481376 (PRKAA2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100481376 (PRKAA2)
   05410 Hypertrophic cardiomyopathy
    100481376 (PRKAA2)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100481376 (PRKAA2)
   04932 Non-alcoholic fatty liver disease
    100481376 (PRKAA2)
   04931 Insulin resistance
    100481376 (PRKAA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100481376 (PRKAA2)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aml04131]
    100481376 (PRKAA2)
   03029 Mitochondrial biogenesis [BR:aml03029]
    100481376 (PRKAA2)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.31  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
     100481376 (PRKAA2)
Protein kinases [BR:aml01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   100481376 (PRKAA2)
Membrane trafficking [BR:aml04131]
 Autophagy
  Other autophagy associated proteins
   Others
    100481376 (PRKAA2)
Mitochondrial biogenesis [BR:aml03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100481376 (PRKAA2)
  Mitophagy factors
   Other mitophagy factors
    100481376 (PRKAA2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr AMPK_alpha_AID AdenylateSensor Kinase-like ABC1 Kdo APH
Other DBs
NCBI-GeneID: 100481376
NCBI-ProteinID: XP_034509140
Ensembl: ENSAMEG00000017253
Position
2:31114375..31152074
AA seq 532 aa
MTASFFFFFSLVGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLY
QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDL
KPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSC
GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIK
DIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQL
AVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSTMHIPPGLKPHPERMPPLIADSPKA
RCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRV
RRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRS
SFDSVTAESHSLSGSLTGSLTGSTLSSVPPRLGSHTMDFFEMCASLITTLAR
NT seq 1599 nt   +upstreamnt  +downstreamnt
atgacagcaagttttttctttttcttttctttagttggagaacatcaattgacaggccat
aaagtggcagttaaaatcttaaatagacagaagattcgcagtttagatgttgttggaaaa
ataaaacgagaaattcaaaacctaaaactctttcgtcatcctcatataatcaaactatac
caggtgatcagcactccaacagatttttttatggtgatggaatatgtgtctggtggtgaa
ttatttgactacatctgtaaacatggacgggttgaagaggtggaagcaaggcggctcttt
cagcagattctgtcagctgtggattactgtcataggcatatggtggttcatcgagacctg
aaaccagagaatgtgctgttggatgctcacatgaatgccaagatagctgattttggattg
tctaatatgatgtcagatggtgaatttctgcgaaccagttgtggatctccaaattatgca
gcacctgaagtcatctcaggcagattgtatgcaggtcctgaagttgatatctggagctgt
ggtgttattttgtatgcccttctttgtggcaccctcccatttgatgatgagcatgtacct
acgttatttaagaagatccgagggggtgttttttatatcccagaatatctcaatcgttct
gttgccactctcttgatgcatatgctgcaggttgaccccctgaaacgagcaaccatcaaa
gatataagagagcatgaatggtttaaacaagatttgcccagttacttatttcctgaagac
ccctcctatgatgctaacgtcattgatgatgaggctgtgaaagaagtgtgtgaaaaattt
gagtgtacagaatcagaagtaatgaacagtttatatagtggtgaccctcaagaccagctt
gcagtggcttatcatcttatcattgacaatcggagaataatgaaccaagccagtgagttc
tacctcgcctctagtcccccaacaggttcttttatggatgatagtaccatgcatattccc
ccaggcctgaaacctcatccagaacggatgccacctcttatagcagacagccctaaagcg
agatgtccattggatgcactgaacacaactaagcccaaatctttagctgtgaaaaaagcc
aagtggcatcttggaatcagaagtcaaagcaaaccgtatgacattatggctgaggtctac
cgagctatgaagcagctggattttgaatggaaggtagtgaatgcataccatcttcgtgta
agaaggaaaaatccagtgactggcaattatgtgaaaatgagcttacaactttacctggtt
gacaacagaagctatcttttggactttaaaagcattgatgatgaggtggtggagcagagg
tctggttcttcaacacctcagcgttcctgttctgctgctggcttacatagaccaagatca
agttttgattctgtaactgcagagagccattcactttctggctctctcactggctctttg
accggaagcacattgtcttcagttccaccccgcctaggcagtcacaccatggattttttt
gaaatgtgtgccagtctgatcactaccttagcccgttga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (20)   
   KEGG PATHWAY (20)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (75)   

Download RDF
DBGET integrated database retrieval system