KEGG   Amycolatopsis methanolica: AMETH_2523
Entry
AMETH_2523        CDS       T03230                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
amq  Amycolatopsis methanolica
Pathway
amq00300  Lysine biosynthesis
amq00550  Peptidoglycan biosynthesis
amq01100  Metabolic pathways
amq01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:amq00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    AMETH_2523 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    AMETH_2523 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    AMETH_2523 (murF)
Enzymes [BR:amq01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     AMETH_2523 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AIJ22615
UniProt: A0A076MVA4
Position
2618617..2620086
AA seq 489 aa
MIPLTLEQIAAVTGGRLHRTDGRETVTGSVEFDSRRLTPGGLFVALPGEKVDGHAFAGKA
MESGAAGVLAAREVDARAVIVPPLPPGQAHERALALTGDKDGSGAAVLAALAKLARHVVI
ELSRGGLAVVGVTGSSGKTSTKDLIAQLLEPMGETVAPPGSFNNELGHPWTALRADERTR
HLVLEMSARGPGHIAHLAEVAPPRIGAVLNVGSAHVGEFGSREAIAKTKGELVEALPSVD
EGGVAVLNLDDPLVAAMASRTTARVVGVGEHPDAQVRAEDITLDEQARASFRLITPAGEA
PVTLSLYGEHHVGNALTAAAIALELGATVEQVAQRLSAAQRRSARRMEVTTRADGVVVMN
DSYNANPESMRAALKTLASASRGKRSWAVLGVMGELGADSVSAHDEIGRLAVRLNISRLV
VVGDEAAAMHQGASHEGSWGEESVLVPDAAAAIDLLREQLEPGDVVLVKASKVAELWLVA
DALLKEGVA
NT seq 1470 nt   +upstreamnt  +downstreamnt
ttgatcccgctgaccctggagcagatcgccgccgtcaccggcgggcggctgcaccgcacc
gacggacgcgagacggtcaccggcagcgtcgagttcgactcgcgccgcctcaccccgggc
gggctgttcgtcgccctgcccggcgagaaggtcgacgggcacgccttcgccggcaaggcg
atggagagcggcgccgccggcgtactggccgcgcgcgaggtcgacgcccgcgcggtgatc
gtgccgccgctgccgcccggccaggcgcacgagcgcgcgctggcgctgaccggcgacaag
gacggctccggcgccgccgtgctggccgcgctggccaagctggcccggcacgtggtgatc
gagctgtcccgcggcgggctcgccgtcgtcggggtcaccggctcctccggcaagacctcc
accaaggacctcatcgcgcagctgctggagccgatgggcgagacggtcgcgccgcccgga
tcgttcaacaacgagctgggccacccgtggaccgcgctgcgcgccgacgagcgcacccgc
cacctggtgctggagatgtccgcccgcggcccaggccacatcgcgcacctcgcggaggtc
gccccgccgcgcatcggcgcggtgctcaacgtgggcagcgcccacgtcggcgagttcggc
tcgcgcgaggcgatcgccaagaccaagggcgagctggtcgaggccctgccgtcggtggac
gagggcggggtcgcggtcctcaacctggacgacccgctggtcgcggcgatggcgagccgc
acgacggcccgcgtcgtcggtgtcggcgagcacccggacgcgcaggtgcgcgccgaggac
atcaccctcgacgagcaggcccgcgcctccttccggctcatcactcccgccggggaggcg
ccggtgacgctgtcgctgtacggcgagcaccacgtcggcaacgcgctcacggccgccgcg
atcgcgctcgaactgggcgcgaccgtcgagcaggtcgcgcagcgcctgtcggccgcccag
cgccgctccgcgcgccgcatggaggtcaccaccagggccgacggcgtcgtggtcatgaac
gactcctacaacgccaacccggagtcgatgcgcgccgcgctcaagacactggcctcggcc
agccgcggcaagcggtcttgggcggtcctcggtgtgatgggcgaactcggtgccgatagc
gtgtccgcgcacgacgagatcggccgcctcgcggtccggctcaacatcagcaggctcgtg
gtggtcggagacgaggccgccgcgatgcaccagggcgccagccacgagggttcgtggggt
gaggagtccgtgctggtgcccgacgccgccgccgcgatcgacctcctgcgcgagcagctg
gaacccggtgacgtcgtgctcgtgaaggcttcgaaggtcgccgagctctggctcgtcgct
gacgcactgctcaaggaaggtgttgcgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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