KEGG   Amycolatopsis sp. YIM 10: YIM_02030
Entry
YIM_02030         CDS       T06270                                 
Symbol
leuA1
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
amyy  Amycolatopsis sp. YIM 10
Pathway
amyy00290  Valine, leucine and isoleucine biosynthesis
amyy00620  Pyruvate metabolism
amyy01100  Metabolic pathways
amyy01110  Biosynthesis of secondary metabolites
amyy01210  2-Oxocarboxylic acid metabolism
amyy01230  Biosynthesis of amino acids
Module
amyy_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:amyy00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    YIM_02030 (leuA1)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    YIM_02030 (leuA1)
Enzymes [BR:amyy01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     YIM_02030 (leuA1)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer PP_kinase_C
Other DBs
NCBI-ProteinID: QFU85633
UniProt: A0A5P9PBR8
Position
complement(402991..404775)
AA seq 594 aa
MSTSDKPAASRIRKPSRPAPADQPQWNPQRGTSMPVHRYRPWFELVEDIQLADRTWPDRR
IERAPLWCAVDLRDGNQALIDPMSPARKRKFFELLVRMGYKEIEVGFPAASQTDFDFVRE
IIDEGAIPDDVHIQVLTQCRPELIERTFQALEGAPRAIVHIYNSTSILQRRVVFREEREG
IKKIALQAAELVVEYAAKYSDTDFRFQYSPESYTGTELSYAAEVCNAVTDIWQPTPARPA
ILNLPATVEMATPNIYADSIEWMHRNLERRDSVILSLHPHNDRGTGIAAAELGYQAGADR
IEGCLFGNGERTGNVDLVALGMNLYSQGIDPQIDFSDMDEIKRTVEYCNQLPVPERSPWG
GDLVFTAFSGSHQDAINKGLDALGRAAEKAGVPVDEHPWEVPYLPIDPKDVGRNYEAVIR
VNSQSGKGGVAYIMKSEHQLDLPRRLQIEFSKTVQRHTDTAGGEVDPTTMWNAFSAEYLE
PKVPLELVRQHVTDSGGGEYEIAATVRVDGDEHDITGRGNGPIASFFDALAGVGFDLRLL
DYSEHTLSPGDDAKAASYIECAIDDRVFWGVGVDPSIVTASLRAVVSAVNRSHR
NT seq 1785 nt   +upstreamnt  +downstreamnt
atgagcacgtcagacaagcccgcggccagccggatccgcaagccctcccggcccgccccc
gcggaccagccccagtggaacccccagcgcggcacctccatgccggtgcaccgctaccgc
ccgtggttcgagctggtcgaggacatccagctggccgaccgcacctggccggaccggcgc
atcgagcgcgcgccgctgtggtgcgcggtcgacctgcgcgacggcaaccaggcgctgatc
gacccgatgtcccccgcccgcaagcgcaagttcttcgaactgctggtgcgcatgggttac
aaggagatcgaggtcggcttcccggccgccagccagaccgacttcgacttcgtccgcgag
atcatcgacgagggcgcgatccccgacgacgtgcacatccaggtgctgacccagtgccgc
ccggagctgatcgagcgcaccttccaggcgctggagggcgcgccgcgcgcgatcgtccac
atctacaactcgacctcgatcctgcagcgccgggtggtcttccgcgaggagcgcgagggc
atcaagaagatcgcgttgcaggccgccgagctggtggtcgagtacgcggcgaagtactcc
gacaccgacttccggttccagtactcgcccgagtcctacaccggcaccgagctgtcctac
gcggccgaggtgtgcaacgcggtcaccgacatctggcagccgaccccggcccgcccggcg
atcctgaacctgcccgccaccgtcgagatggccacgccgaacatctacgcggactcgatc
gagtggatgcaccgcaacctggagcgccgcgactcggtgatcctgtcgctgcacccgcac
aacgaccgcggcaccggcatcgccgccgccgagctgggttaccaggcgggcgcggaccgg
atcgagggttgcctgttcggcaacggcgagcgcaccggcaacgtggacctggtcgcgctg
ggcatgaacctgtacagccagggcatcgacccgcagatcgacttctccgacatggacgag
atcaagcgcacggtcgagtactgcaaccagctgccggtgcccgagcgcagcccgtggggt
ggtgacctggtgttcaccgccttctccggcagccaccaggatgcgatcaacaaggggctg
gacgcgctgggccgggccgccgagaaggcgggcgtaccggtggacgagcacccgtgggag
gtcccgtacctgccgatcgacccgaaggacgtcggtcgcaactacgaggccgtgatccgg
gtcaactcgcagtccggcaagggcggcgtcgcctacatcatgaagagcgagcaccagctg
gacctgccgcggcgcttgcagatcgagttctccaagaccgtccagcggcacaccgacacc
gccggtggcgaggtcgacccgacgaccatgtggaacgccttctcggccgagtacctggag
ccgaaggtgccgctggagctggtgcgccagcacgtgaccgacagcgggggcggcgagtac
gagatcgccgcgacggtccgggtggacggcgacgagcacgacatcaccggccgcggcaac
ggcccgatcgcctcgttcttcgacgcgctggccggggtcggcttcgacctgcggctgctg
gactacagcgagcacacgctctcccccggtgacgacgcgaaggcggcgtcctacatcgaa
tgcgcgatcgacgaccgcgtgttctggggggtcggcgtcgacccgtcgatcgtcaccgct
tcactgcgcgccgtggtctccgcggtgaaccgctcgcaccggtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (23)   

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