KEGG   Actinosynnema pretiosum: CNX65_11265
Entry
CNX65_11265       CDS       T05092                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
apre  Actinosynnema pretiosum
Pathway
apre00270  Cysteine and methionine metabolism
apre00450  Selenocompound metabolism
apre00670  One carbon pool by folate
apre01100  Metabolic pathways
apre01110  Biosynthesis of secondary metabolites
apre01230  Biosynthesis of amino acids
apre04980  Cobalamin transport and metabolism
Module
apre_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:apre00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CNX65_11265 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CNX65_11265 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CNX65_11265 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    CNX65_11265 (metH)
Enzymes [BR:apre01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CNX65_11265 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: ATE53804
UniProt: A0A290Z495
Position
2484910..2488446
AA seq 1178 aa
MSDRVSSPLLDALTERVVVADGAMGTMLQSFDLSLDDFAGHEGCNEILNTTRPDVVRAVH
RGYLEAGADAVETNTFGANLSNFSDYGIQDRIFELSRLGAQLAREAADEHAEPGRPRFVL
GSVGPGSKLPTLGHVAYSVLRDSYVEQIRGLLVGGSDAIIVETSQDLLQTKAAIVAAKRA
MDAEGLRVPIIAQVTVETTGTMLLGSEIGAALTALEPLGIDLVGLNCATGPAEMSEHLRH
IAKHARIPLSVMPNAGLPQLGPNGAVYPLGPEELAQALRGFATEFGARLVGGCCGTTAEH
VRQVAAAVRDLGPTTRRPRPEPGVSSLYQAVPFQQDASVLMIGERTNANGSKAFREAMLA
DRWDDCVGIARDQTRDGAHLIDLNVDYVGRDGVADMSALASRLATASTLPIMLDSTEPEV
LQAGLEHLGGRCAVNSVNYEDGDGPDSRFQRIMRLVAEHGAAVVGLCIDEEGQARTAEWK
VRVAVRIIEDLVGNWGLRHGDIIIDCLTFPISTGQEEVRRDGVETIEAIRELKRRYPEVR
TTLGLSNVSFGLNPAARQVLNSVFLHECVQAGLDTAIVHASKIVPMARIPDEQRAVALDL
VHDRRREGYDPLQRLMELFEGVTTSASKATRAQELAALPLFERLQRRIVDGERNGLEADL
DEALTQRPALQIINDTLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMERSD
DGGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVINLGIKQPISAILDAAENHRADAIG
MSGLLVKSTVIMKENLEEMNSRGVAARWPVLLGGAALTRAYVENDLTDTYLGEVRYARDA
FEGLRLMDAVMAAKRGESPLVDPEAERKAAERKARRERSLRIAAERKAAQPEPEPVSRSD
VAADLPVPTPPFWGTRVVKGVPLGDYSALLDERATFMGQWGLRGSRGSGPSYEELVETEG
RPRLRYWLERLATEGVLAHAAVVYGYFPCVSEGDSLVILGEPSVDAPEVTRFAFPRQKRD
RRLCLADFWRPRESGEVDVVPFQLVTMGQPIADYANELFAKDAYREYLEVHGLGVQLTEA
LAEYWHKRVREELTWPGGGVVAAEDPADVEEYFKLGYRGARYSLGYGACPDMEDRTKVVA
LLEPGRIGVKLSEELQLHPEQSTDAFIAHHPEAKYFNA
NT seq 3537 nt   +upstreamnt  +downstreamnt
atgtcggatcgtgtctcgtcccccctgctggacgcactcaccgaacgcgtggtcgtggcc
gacggggccatgggcaccatgctccagtcgttcgacctgtccctcgacgacttcgcaggc
cacgagggctgcaacgagatcctgaacaccacccggcccgacgtggtgcgcgccgtgcac
cgcggctacctggaggcgggcgccgacgcggtcgagacgaacaccttcggcgcgaacctc
tccaacttctccgactacggcatccaggaccgcatcttcgagctgtcccgcctcggcgcc
cagctcgcccgcgaggccgccgacgagcacgccgagccgggccgcccgcgcttcgtgctc
ggctcggtcggccccggctccaagctgcccaccctcggccacgtcgcctactcggtgctg
cgcgactcctacgtggagcagatccggggcctgctggtcggcggctccgacgccatcatc
gtcgagacctcgcaggacctgctccagaccaaggcggcgatcgtcgccgccaagcgcgcc
atggacgccgagggcctgcgcgtgccgatcatcgcccaggtcaccgtcgagaccaccggc
accatgctgctgggctccgagatcggcgccgccctcaccgccctcgaaccgctcggcatc
gacctggtcggcctgaactgcgccaccggccccgccgagatgagcgagcacctgcggcac
atcgccaagcacgcccgcatcccgctgtcggtcatgcccaacgcgggcctgccgcagctc
ggcccgaacggcgcggtctacccgctcggccccgaggagctggcgcaggcgctgcgcggg
ttcgccaccgagttcggcgcccgcctggtcggcggctgctgcggcaccaccgccgagcac
gtccgccaggtcgccgccgccgtgcgcgacctcggccccaccacccgccgcccgcgcccc
gagccgggcgtgtcctcgctctaccaggccgtgccgttccagcaggacgcgtccgtgctg
atgatcggcgagcgcaccaacgccaacggctccaaggccttccgcgaggccatgctcgcc
gaccgctgggacgactgcgtgggcatcgcccgcgaccagacccgcgacggcgcgcacctg
atcgacctcaacgtcgactacgtgggccgcgacggcgtcgccgacatgtccgcgctcgcc
tcccgcctggccaccgcgtccaccctgccgatcatgctcgactccaccgagcccgaggtg
ctccaggcgggtctcgagcacctgggcgggcgctgcgcggtcaactcggtcaactacgag
gacggcgacggccccgactcgcggttccagcgcatcatgcggctggtcgccgagcacggc
gcggccgtcgtcggcctgtgcatcgacgaggagggccaggcccgcaccgccgagtggaag
gtccgggtggccgtccgcatcatcgaggacctggtcggcaactggggcctgcggcacggc
gacatcatcatcgactgcctgaccttccccatctccaccggccaggaggaggtgcggcgc
gacggcgtggagaccatcgaggccatccgcgagctcaagcgccgctaccccgaggtgcgc
accacgctcgggctgtccaacgtgtccttcggcctcaacccggccgcccgccaggtgctg
aactcggtgttcctgcacgagtgcgtgcaggccgggctggacaccgcgatcgtgcacgcc
tcgaagatcgtgccgatggcgcgcatccccgacgagcagcgcgcggtagccctggacctg
gtccacgaccgccgccgcgagggctacgacccgctgcagcggctcatggagctgttcgag
ggcgtcaccacctccgcctccaaggccacccgcgcccaggagctggccgcgctgccgctg
ttcgagcggttgcagcggcgcatcgtggacggcgagcgcaacggcctggaggccgacctg
gacgaggcgctgacccagcggcccgcgctccagatcatcaacgacaccctgctggcgggc
atgaagacggtcggcgagctgttcggctccggccagatgcagctgccgttcgtgctccag
tccgccgaggtcatgaagaccgccgtcgcgcacctggagccgcacatggagcgctccgac
gacggcggcaagggccgcatcgtgctcgccaccgtcaagggcgacgtgcacgacatcggc
aagaacctggtggacatcatcctgtccaacaacggctacgaggtcatcaacctcggcatc
aagcagcccatcagcgccatcctcgacgccgccgagaaccaccgcgccgacgccatcggc
atgtccggcctgctcgtcaagtccacggtgatcatgaaggagaacctggaggagatgaac
tcgcgcggggtcgccgcccgctggccggtgctgctcggcggggccgcgctcacccgcgcg
tacgtggagaacgacctcaccgacacctacctcggcgaggtccgctacgcccgcgacgcg
ttcgagggcctgcggctgatggacgcggtcatggcggccaagcgcggcgagtccccgctg
gtcgacccggaggccgagcgcaaggccgccgagcgcaaggcccgccgcgagcggtcgctg
cgcatcgccgccgagcgcaaggccgcccagcccgagccggagccggtgtcccgctcggac
gtggccgccgacctgcccgtccccaccccgccgttctggggcacccgcgtggtcaagggc
gtgccgctgggcgactactcggcgctgctcgacgagcgcgccacgttcatgggccagtgg
gggctgcgcggctcgcgcggcagcggaccgtcctacgaggagctggtcgagaccgagggc
cgcccccggctgcgctactggctggagcggctggccaccgagggcgtcctcgcgcacgcc
gccgtggtctacgggtacttcccgtgcgtgtccgagggcgactcgctggtgatcctgggc
gagccgtcggtggacgcgcccgaggtgacccggttcgcgttcccccggcagaagcgcgac
cggcggctgtgcctggccgacttctggcgaccgcgcgagtccggcgaggtcgacgtggtg
ccgttccagctggtcaccatggggcagccgatcgccgactacgccaacgagctgttcgcc
aaggacgcctaccgcgagtacctggaggtgcacggcctgggcgtgcagctcaccgaggcg
ctcgccgagtactggcacaagcgggtgcgcgaggagctgacctggccgggcggcggggtc
gtcgcggccgaggacccggccgacgtggaggagtacttcaagctcggctaccggggcgcc
cggtactccctgggctacggggcctgccccgacatggaggaccggaccaaggtcgtcgcg
ctgctcgaaccgggccgcatcggcgtgaagctgtccgaggagctccagctgcaccccgag
cagtccacggacgcgttcatcgcccaccaccccgaggccaagtacttcaacgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (32)   

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