KEGG   Actinoplanes sp. SE50/110: ACPL_1029
Entry
ACPL_1029         CDS       T02044                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ase  Actinoplanes sp. SE50/110
Pathway
ase00290  Valine, leucine and isoleucine biosynthesis
ase00620  Pyruvate metabolism
ase01100  Metabolic pathways
ase01110  Biosynthesis of secondary metabolites
ase01210  2-Oxocarboxylic acid metabolism
ase01230  Biosynthesis of amino acids
Module
ase_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ase00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    ACPL_1029 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ACPL_1029 (leuA)
Enzymes [BR:ase01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     ACPL_1029 (leuA)
SSDB
Motif
Pfam: HMGL-like
Other DBs
NCBI-ProteinID: AEV81926
UniProt: G8SK27
Position
complement(1059144..1060538)
AA seq 464 aa
MDADRKLRAFTMMVAMGFKEIEVGYPSASGLDFDFVRLLAERDDLVPDDVTVVVFTAARD
DLIRRTVASIDGLARAVVHMYTATAPTWRDVVLRASRAGLRTRILHAAGVVLSETDRLAH
TYTRFEFSPEVFNLTEPEFVLDVCNAVTGRWDAAPDRPVIHNLPATVECATPNVYADQIE
WMSRHLDRRNDVILSVHPHNDRGTGVACAELAVLAGAQRVEGCLFGNGERTGNVDLVTLA
MNLYTQGIDPKLDFSDIDAVRRTVEHYNRMPVPDRHPYAGDLVYTAFSGTHQDAIDKGMI
FHAKRAAALGVPESEAPWEVPYLPVDPADVGRSYEAVIRVNSQSGKGGVAYLLRTGHGLD
LPPGLRVEVGALAQAASEGRAGGGELTPAELWSLFRDEYLVHPGFPVDLDGVEVIEEVTG
NFREAIISYVRCRIAEVERWGAGVGSTPEAARHAAMSSAARRAV
NT seq 1395 nt   +upstreamnt  +downstreamnt
atggacgccgaccgcaaactgcgcgccttcaccatgatggtcgcgatgggtttcaaggag
atcgaggtcggctacccgtcggcgagcgggttggacttcgacttcgtccggttactggcc
gagcgtgacgacctggtcccggacgacgtcaccgtggtcgtcttcaccgccgcccgggac
gacctgatcaggcggaccgtggcatcgatcgacggcctggccagggcggtcgtgcacatg
tacacggcgaccgcaccgacctggcgcgacgtggtgctgcgggcgtcccgggccgggctc
aggacaaggatcctgcacgcggccggggtggtgctgtccgaaactgatcgactggctcac
acgtacacccgcttcgagttcagtcctgaggtcttcaacctgaccgaaccggagttcgtg
ctggacgtctgcaacgcggtcaccgggcggtgggacgccgccccggaccggccggtgatc
cacaacctgccggccacggtcgaatgcgccaccccgaacgtgtacgccgaccagatcgaa
tggatgagccggcacctggaccggcgcaacgacgtgatcctgtcggtgcacccgcacaac
gaccgcggcaccggggtggcctgcgccgaactggccgtgctggccggcgcgcaacgggtc
gagggctgcctgttcggcaacggtgaacgcaccggcaacgtcgacctggtcacgctggcg
atgaacctgtacacccagggcatcgacccgaagctggacttctcggacatcgatgcggtg
cgccggaccgtcgagcactacaaccggatgcccgtgccggatcgccacccgtacgccggc
gacctggtctacaccgcgttctccggcacccaccaggacgccatcgacaaaggcatgatc
ttccacgccaaacgcgccgccgcgctgggcgtgcccgagtccgaggcgccgtgggaggtg
ccgtacctgccggtcgacccggccgacgtgggccgctcctacgaggcggtgatccgggtg
aacagccagtccggcaagggtggggtggcctacctgctgcgcaccgggcacggcctggac
ctgccgcccggcctgcgggtcgaggtcggcgcgctggcccaggccgcgagcgagggacgg
gccggcggcggcgagctgaccccggccgaactgtggtcgctgttccgcgacgaatacctg
gtccaccccggattcccggtcgacctggacggcgtcgaggtgatcgaggaggtcaccgga
aacttccgggaggcgatcatttcgtacgttcgttgccggatcgccgaggtggaacgctgg
ggtgccggcgtcgggtcgaccccggaagccgcccggcacgccgcgatgagcagcgccgcc
cgtcgcgccgtctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (22)   

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