KEGG T06105: 109594638

Aethina tumida (small hive beetle): 109594638

Entry

109594638         CDS       T06105

Name

(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic isoform X1

K00288

methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]

Organism

atd Aethina tumida (small hive beetle)

Pathway

atd00670

One carbon pool by folate

atd01100

Metabolic pathways

atd01240

Biosynthesis of cofactors

Module

atd_M00141

C1-unit interconversion, eukaryotes

Brite

KEGG Orthology (KO) [BR:atd00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    109594638
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:atd04147]
    109594638
Enzymes [BR:atd01000]
1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     109594638
3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     109594638
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     109594638
Exosome [BR:atd04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   109594638

SSDB

Motif

Pfam:

FTHFS THF_DHG_CYH_C THF_DHG_CYH FlgI

Other DBs

NCBI-GeneID:

109594638

NCBI-ProteinID:

XP_019865430

EnsemblRapid:

ENSATDG00005004045

Position

1:complement(join(52780092..52780181,52780510..52780662,52780718..52781003,52781059..52781740,52781797..52782266,52782326..52782725,52784108..52784219,52784284..52784518,52784649..52784785,52784851..52785049,52785104..52785161,52785357..52785483))

AA seq 982 aa
MAFFQKISVLRLFRLLINLYFSCFLPVSWNNIFLKKKSKYNENIRRMSATTGNILSGTDI
AREIKEQLTKDVAAIKQKLPNFQLGLAIVQVGGREDSNVYIRMKIKAAQEIGINAEHVKL
PKSTTEVELLSKIQKLNADPNVHGIIVQMPLDSDTKIDSHLITDAVAPEKDVDGLNTINE
GRTAIGDLTGFLPCTPNGVIEMIKRTGIQMAGAETVVLGRSKIVGTPAAELLKWNHATVT
VCHSKTKNLKAQCLKADILVVGIGQPELVKGDWVKPGAVVIDCGINAIPDPTKKSGQRLV
GDVAYEEARKNASYITPVPGGVGPMTVAMLMKNTVQSAQKSANRILNAKWNLKHLPLKLL
NPVPSDIAISRAQEPKNIVQLAEEIGLYPGEVSPYGTTKAKISLSVLDRLKEQQNGKYVV
LAGITPTPFGEGKSTTLLGLVQALSTQLDKNVFATLRQPSQGPTFGIKGGAAGGGYSQII
PMEDMNLHLTGDIHAITAAHNLLAAQLDARMFHEATQTDKALFDRLVPTIKGVRKFSDIQ
IRRLKRLGINKTDPNSLTDEEKARWARLNIDPNHVTWDRVLDVNDRYLREITVGQSPTEK
GLSRKTGFTISVASEIMAILALSNDLKDFKERLSKMVVAFDKNGKPVIADDLGITGALMV
LLLDTIQPTLLQSLEGTPALVHAGPFANIAHGSSSIIADKIALKLVGKDGFCVTEAGFSS
EIGMEKFFNIKCRASGLTPNAVVLVSTVRALKMHGGGPAVTPGAPLAPEYTQENLELVRK
GLPNLLKHISNGVKYGVPVVVAINHRDGDTDAEVQLIAEAAKQAGAYDAVVSKHWALGGL
GAKALAEALVKATEKPSNFKFLYDTNLPLQEKANIIAKEMYGAAKVTFTEKALEKIKKYE
EEGYGKLPICMAKTQSSLTGDPKIKGAPTGFTIDVFDVSISAGAQFAVLYAGEINKMPGL
PTRPAIYDIDVDTETGEITGLF

NT seq 2949 nt +upstreamnt +downstreamnt
atggctttttttcagaaaattagtgttttaagattatttaggttgctaattaacctatac
ttttcgtgtttccttcccgtatcttggaacaacatttttttaaagaaaaaatcaaaatac
aatgaaaacattagaagaatgtccgccaccacaggaaatattttatctggaactgacata
gccagggagatcaaggaacagttgacaaaggatgtagctgcaattaagcaaaagctgccc
aatttccaactggggttggctattgtacaagtgggtggtagagaggactccaatgtgtac
atccggatgaaaattaaagctgcccaagaaattggtatcaatgctgaacatgttaaactg
ccaaaatctaccactgaagtggagttgctgagtaagattcaaaaacttaatgctgatcca
aatgtgcatggaattattgtacaaatgcctttggattctgacacaaagattgactcacat
ttaatcactgatgcagttgctcctgagaaggatgtggatggtcttaacacaatcaacgag
gggcgaacagctattggcgacttaacaggtttcttgccatgcactccaaacggcgttatt
gaaatgataaaacgaactggaattcaaatggcaggtgctgaaactgttgtattgggcagg
agcaaaatcgttggaacacccgctgcagaacttcttaaatggaaccacgcgactgttacc
gtctgccattcaaaaactaaaaatttgaaagctcaatgccttaaagcggatattttagtc
gttggtattggacaaccggaattagtgaaaggtgattgggtgaagccaggagccgtagtc
attgattgtggaataaatgccattccagatcccaccaaaaaatctggccaaagactggtc
ggagatgttgcatatgaagaggctcgtaaaaatgcctcttacatcacccccgtcccaggt
ggcgtcggtcccatgactgtagccatgctcatgaagaacaccgtacaaagtgcccagaaa
tcagccaaccgtattttgaacgcgaaatggaacctgaaacatttgccgttaaaacttctg
aatccagttcccagcgacattgccatttctagagcacaggaacccaagaacatcgttcaa
ttggccgaagaaattggattgtatccgggagaggtttctccctatggtaccaccaaggca
aaaatttcactttcggttcttgacagactgaaagaacaacaaaacggaaaatacgtcgtt
cttgctggtattactccgactccatttggcgaaggcaaaagtaccacccttttaggtttg
gtacaagccctgtccactcaactggataagaatgtgttcgctacacttagacaaccgtct
caaggaccaaccttcggaatcaaaggtggcgctgctggtggtggatactctcaaatcatc
cccatggaagacatgaacttgcatttaaccggagacattcacgctattactgcggctcac
aacttactggctgcccaattggatgcaagaatgttccatgaagccacccaaacggataaa
gctctattcgatagattggtaccaacgattaagggtgtgaggaagttctctgacatccag
atcaggagattgaagcgactgggaattaacaaaactgatcccaactctttgactgatgaa
gaaaaggccagatgggccaggttgaacattgaccctaaccatgttacttgggatagagtg
ttggatgtcaacgacagatatttacgtgaaatcactgtgggccagtctccaacagagaaa
ggtctttcccgtaaaacgggcttcaccattagtgtggccagtgaaattatggctattctt
gccctctctaatgatcttaaagatttcaaggagagactatctaaaatggtcgtcgctttt
gataaaaacggcaaacctgtgattgccgatgatttaggaattactggggcactgatggta
ttgcttctagacaccattcaaccaactttgttgcaatctctggagggtactcccgctctt
gtacatgctggacctttcgctaacattgcgcacggttcaagctctataattgctgataag
attgcactgaaattggttggaaaggatggtttctgcgttactgaagctggattttcgtct
gaaattggcatggagaaattcttcaacatcaaatgtagagcatctggacttactccgaat
gctgtggtgttggtttcaactgttagagcattgaaaatgcacggtggtggtcctgccgta
acgcctggagctcctcttgctcctgagtatacccaagaaaacctggaattagtcagaaaa
ggccttcccaatttactaaaacatattagcaacggtgttaaatacggggttcccgtagta
gttgccattaatcacagagacggagatacagacgcagaagtccaacttattgctgaggct
gccaaacaagctggtgcttatgatgctgttgtatctaaacattgggctttaggaggtctt
ggtgctaaagctttggcggaagcacttgtcaaagctactgagaagcccagcaactttaag
ttcctttacgacactaatttacctttgcaagaaaaagctaatatcatcgctaaggaaatg
tatggtgccgcgaaagttacttttaccgaaaaagcgctggagaaaattaaaaaatacgaa
gaagaaggatatggaaaattgccaatttgcatggcaaaaactcagtcatcacttactggt
gatcccaaaattaaaggtgccccaactggcttcaccattgatgtttttgatgtatccatc
tctgctggtgcacagtttgctgtactctatgctggagagatcaataaaatgcctggatta
ccaactaggccagcaatttacgacattgacgtggatactgaaactggagaaataactgga
ctattctaa

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