KEGG   Aegilops tauschii (wheat D): 109782258
Entry
109782258         CDS       T04345                                 
Name
(RefSeq) putative bifunctional dihydrofolate reductase-thymidylate synthase isoform X1
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
ats  Aegilops tauschii (wheat D)
Pathway
ats00240  Pyrimidine metabolism
ats00670  One carbon pool by folate
ats00790  Folate biosynthesis
ats01100  Metabolic pathways
ats01232  Nucleotide metabolism
ats01240  Biosynthesis of cofactors
Module
ats_M00126  Tetrahydrofolate biosynthesis, GTP => THF
ats_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ats00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    109782258
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    109782258
   00670 One carbon pool by folate
    109782258
Enzymes [BR:ats01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     109782258
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     109782258
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 109782258
NCBI-ProteinID: XP_020196441
Position
Unknown
AA seq 576 aa
MLSSKLLGARAGISTLCTTATPLLSTRTTTISRWTRHKSLEAINKLKSSCFHQSQMMAGV
TNGNSHSDIQRKYQVVVAATREMGIGKDGALPWKLPSDLKFFKDLTMATADPSKKNAVIM
GRKTWESIPTKFRPLPGRLNVILTRSDSSDYATVENVVTCGSLDSSLELLASAPYSSTIE
KAFLIGGGQVLRELLNASACEAIHLTDIESTIECDTFIPPIDPLVFHPWYSSSPVVENNI
RHSFATFVRVRKSAEEANDSNLSELTSNDAKKKKFEIQIFSFLPKMIFEKHDEYQYLNLV
QDILRSGARKNDRTGTGTISKFGCQMRFNLRKNFPLLTTKRVFWRGVLEELLWFISGSTN
AKVLQEKNIRIWDGNASREYLDSIGLSQREEGDLGPVYGFQWRHFGAEYTDMHADYTGKG
FDQLADVINKIKNNPDDRRIIMSAWNPTDLKKMALPPCHMFAQFYVENGELSCQMYQRSA
DMGLGVPFNIASYSLLTCMIAQVCDLSPGDFVHVMGDAHVYSTHVQALEEQLQKQPKPFP
ILKINPLKKDIDAFVASDFKLVSYDPHQKIEMKMAV
NT seq 1731 nt   +upstreamnt  +downstreamnt
atgttatcatcaaagctactcggcgcgcgagccggcatctccactctatgcacgaccgcc
acaccattgttgagcacgcgtaccaccacaatttctcgttggacaaggcataaatctctt
gaggccatcaacaaactgaagtcttcctgcttccatcaatctcaaatgatggcaggtgtc
acaaatggcaattcacacagtgatattcagagaaaatatcaagttgtggttgctgctacc
cgtgagatgggcattgggaaggacggagcattgccatggaagctgcctagtgaccttaag
ttttttaaggatctcacaatggctacagcagacccatcaaagaaaaatgctgttataatg
ggaaggaaaacatgggaaagcatacccactaagttcaggccattgcccggtcgcttgaat
gttatactgactcgttcggacagttctgattatgcaactgttgaaaatgttgtcacctgt
ggaagcttggattcttccctagaactactagcatcagctccctacagctcaacaattgag
aaagcctttctaatagggggtggccaggtactgagggaattgctaaatgcatctgcatgt
gaggccatccatcttactgacatagagtccaccattgagtgtgatactttcattcctcct
attgatccattggtcttccacccatggtattcatcttctccagttgtggagaacaacatt
aggcattctttcgcgacctttgttcgcgttagaaagtcggcagaagaggctaatgactca
aatctcagtgaattaaccagcaatgatgctaagaagaaaaagtttgaaattcagattttt
tcatttctaccaaaaatgatcttcgaaaagcatgatgagtatcagtatctcaatcttgtt
caagatatactacgaagtggtgctcggaaaaatgacagaacaggaacaggaacaatatca
aaatttggttgtcagatgcggtttaacttgaggaagaattttccattacttacaacaaag
agggtgttctggcgtggtgttcttgaagaactgttgtggttcatcagtggctcaacaaat
gcaaaggttttacaggaaaaaaatattcgtatatgggatggcaatgcgtcaagggagtat
cttgacagtattggtctatcacaaagagaggagggtgacttgggaccagtttatggattt
cagtggagacacttcggtgctgaatatactgacatgcatgctgattacacggggaaaggt
tttgatcagttagctgatgtcattaacaagatcaagaataaccctgacgataggcgtatc
attatgtctgcatggaatccaacagatctcaagaagatggcacttccaccttgccacatg
tttgcacagttttatgtcgagaatggagaattatcctgtcagatgtatcaacgttcagct
gacatggggcttggtgtaccattcaacattgcatcatattctcttctgacgtgtatgatt
gcacaagtttgtgatctttctcctggagattttgtccatgtgatgggcgatgcccatgtc
tacagcacgcacgtccaagccttggaggaacaacttcagaagcagcccaagccatttcct
attctgaagataaaccctctgaagaaggatatagacgcgttcgtcgcgtcagactttaag
ctggtctcctacgacccgcaccagaagatagagatgaagatggcagtataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (46)   

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