KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103004826
Entry
103004826         CDS       T03086                                 
Symbol
ERBB4
Name
(RefSeq) erb-b2 receptor tyrosine kinase 4
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu04010  MAPK signaling pathway
bacu04012  ErbB signaling pathway
bacu04020  Calcium signaling pathway
bacu04151  PI3K-Akt signaling pathway
bacu05014  Amyotrophic lateral sclerosis
bacu05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103004826 (ERBB4)
   04012 ErbB signaling pathway
    103004826 (ERBB4)
   04020 Calcium signaling pathway
    103004826 (ERBB4)
   04151 PI3K-Akt signaling pathway
    103004826 (ERBB4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103004826 (ERBB4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103004826 (ERBB4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103004826 (ERBB4)
Enzymes [BR:bacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103004826 (ERBB4)
Protein kinases [BR:bacu01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   103004826 (ERBB4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like Haspin_kinase DUF3951 ABC1
Other DBs
NCBI-GeneID: 103004826
NCBI-ProteinID: XP_007187925
UniProt: A0A384AKS3
Position
Un
AA seq 1298 aa
MKLATGLWVCVSLLVAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRKAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGRTCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCIGSSIEDCIGLMDRTPLIAAGVIGGLFIMVIVGLT
FAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFG
TVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSP
TIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVL
VKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTI
WELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKEL
AAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNI
PPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFATEQGVPMPYRATTSTIPE
APVAQGATAEIFDDSCCNGTLRKSVAPHVQEDSSTQRYSADPTVFAPEQSPRGELDEEGY
MTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASHGPPKAEDEYVNEPLYLN
TFANALGNTEYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQ
NGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq 3897 nt   +upstreamnt  +downstreamnt
atgaagctggcgacaggactgtgggtctgcgtgagccttctcgtggcggcggggaccgtc
cagcccagcgcttctcagtcagtgtgcgcaggaacagagaataagttgagctctctctct
gacctggaacagcagtaccgagccttgcgcaaatactatgagaactgtgaggtagtcatg
ggcaacctggagataaccagcatcgagcacaaccgggacctctcttttctgcggtctata
agagaagtcacaggctacgtgttggtggctcttaatcagtttcgctatctgcctctggag
aatttacgcattattcgtgggacaaaactttatgaagatcgatatgccttggcaatattt
ttaaactacagaaaagatggaaactttggacttcaagaacttggattgaagaacttgact
gaaatcctaaatggtggagtctatgtagaccagaacaagtttctttgttatacagacaca
attcattggcaagatattgttcggaatccatggccttccaacctgactctggtgtcaaca
aatggtagctcaggatgtggacgttgccataagtcctgcactggccgatgctggggaccc
acagaaaatcattgccagactttgacaaggactgtctgtgcagaacagtgtgatggcaga
tgctacggaccctacgttagtgactgctgtcaccgagaatgtgctggaggttgctcggga
cctaaggacaccgactgctttgcctgcatgaacttcaatgatagcggagcatgtgttact
cagtgtccacaaacttttgtctacaatccaacaacctttcaactggagcataacttcaat
gcaaaatacacctatggagcattttgtgtcaagaagtgcccacataacttcgtggtcgat
tccagttcctgtgtgcgtgcctgccctagttccaagatggaagtagaagaaaatgggatt
aaaatgtgtaaaccttgcactgacatttgcccaaaagcttgtgatggcattggcacagga
tcattgatgtcagctcagaccgtggattctagtaacattgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttccttgtcactggtattcatggggacccttacaatgca
attgaagccatagacccagagaaactgaacgtgtttcggacagtccgagagataacaggt
ttcttgaacatacaatcatggcccccaaacatgaccgacttcagtgttttttctaacctg
gtgaccattggtggaagagtactctatagtggcctttccttgcttatcctcaagcaacag
ggtatcacttctctacaattccaatccctgaaggaaatcagtgcaggaaacatctatatc
actgacaacagcaacctgtgttattatcataccattaactggacaacgctcttcagcaca
atcaaccaaagaatagtgatccgggacaacaggaaagctgaaaactgtactgctgaagga
atggtgtgcaaccatctctgttcaaacgatgggtgttggggacctgggccagaccagtgc
ctgtcatgccgtcgcttcagcaggggaaggacctgcatagagtcttgtaacctctatgac
ggtgaatttcgggagtttgagaatggctccatctgtgtggagtgtgacccccagtgtgag
aagatggaagatggcatcctcacatgccatggaccgggacctgacaactgtacaaagtgc
tcccattttaaggatggcccgaactgtgtggaaaaatgtccagatggcttacagggggca
aacagtttcattttcaagtatgctgatcaggatcgggagtgccacccatgccatccaaac
tgcacccaagggtgcataggctcaagtattgaagactgcatcggcctgatggataggact
cctctaattgcagccggagtcattggcgggctcttcatcatggtcatcgtgggtctaaca
tttgcagtttatgttagaaggaagagcatcaaaaagaaaagagccttaagaagattcctg
gaaacagagttggtagaacccttaacccccagtggtacggcgcctaatcaagctcaacta
cgtattttgaaagaaactgagctcaaaagagtaaaagtacttggttcaggtgcttttgga
actgtttataaaggtatttgggtccctgaaggagaaacagtgaagattcctgtggctatt
aagattcttaatgaaacaactggtcccaaagccaatgtggagtttatggatgaagctctg
atcatggcaagtatggaccatccacacttagtccggttattgggtgtctgtctaagccca
accattcagctggttacacagcttatgccccatggctgcctgttggattatgtccatgaa
cacaaggataacattggatcccagctattgcttaattggtgtgttcagatagctaaggga
atgatgtacctggaagaaagacggcttgttcatcgggatttggcagcccgtaatgtctta
gtgaaatctccaaaccatgtaaaaatcacggattttggactagccaggctcttggaaggt
gatgaaaaagagtataatgctgatggaggaaagatgccaattaaatggatggctttggag
tgtatacactatagaaaattcacccatcagagtgacgtttggagctatggagtcactata
tgggaactgatgacctttggaggaaaaccctatgatggaattccaaccagagaaatcccc
gatttgttagagaaaggagaacgtttgccccagcctcccatctgcactattgatgtttat
atggtcatggtcaaatgttggatgattgatgctgacagtagacctaaatttaaggaactg
gctgctgaattttcgaggatggctcgagaccctcaaagatacctagttattcagggtgat
gatcgtatgaagcttcccagtccaaacgacagcaagttctttcagaatctcttggatgaa
gaggatttagaagatatgatggatgctgaggaatatctggtccctcaggctttcaacatc
ccacctcccatctatacttccagagcaagaatcgactcaaataggagtgaaattggacac
agccctcctcctgcctacacccccatgtcaggaaaccagtttgtgtaccgagatgggggt
tttgctacagaacaaggagtgcccatgccctatagggccaccaccagcacgatcccagaa
gccccagttgctcagggggctaccgccgagatttttgatgactcctgctgtaacggcacc
ttacgcaagtccgtggcaccccacgtccaagaggacagcagcacccagaggtacagcgct
gaccccacagtgtttgccccagaacagagcccacgaggagagctggatgaagaaggttac
atgacccctatgcgagacaaacccaaacaagaatacctgaaccctgtggaagagaaccct
tttgtctctcgaaggaaaaatggagaccttcaagctttggataatcccgaatatcacagt
gcttcccatggtccacccaaggcagaggatgagtatgtgaatgagccactgtacctcaac
acctttgccaacgccttggggaacactgaatacctgaagaacaacgtactgtctgtgcca
gagaaggccaagaaagcattcgacaaccctgactactggaaccacagcctgccaccccgg
agcacccttcagcacccagactacctgcaggagtacagcacaaaatatttttataaacag
aatggacggatccggcctattgtggcagagaatcctgaatacctctctgagttctcgctg
aagccaggcactgtgctgcctcctccgccctacagacaccggaatactgtggtgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (10)   
   Pfam (10)   
All databases (50)   

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