KEGG   Brevibacillus brevis: BBR47_22040
Entry
BBR47_22040       CDS       T00879                                 
Name
(GenBank) putative 5,10-methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
bbe  Brevibacillus brevis
Pathway
bbe00270  Cysteine and methionine metabolism
bbe00450  Selenocompound metabolism
bbe00670  One carbon pool by folate
bbe01100  Metabolic pathways
bbe01110  Biosynthesis of secondary metabolites
bbe01120  Microbial metabolism in diverse environments
bbe01230  Biosynthesis of amino acids
Module
bbe_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:bbe00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    BBR47_22040
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    BBR47_22040
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    BBR47_22040
Enzymes [BR:bbe01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     BBR47_22040
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     BBR47_22040
SSDB
Motif
Pfam: S-methyl_trans MTHFR PEP_mutase
Other DBs
NCBI-ProteinID: BAH43181
UniProt: C0ZBM2
Position
2301583..2303448
AA seq 621 aa
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVVGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPTISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHLACRDRNLIGQQSHLMGLNALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVRMAQT
NT seq 1866 nt   +upstreamnt  +downstreamnt
ttgacgacgagaaagaaagatttacgagcctacttgaaagaccatctcctagtaggagat
ggtgcaatggcgacccagctgcacgggctgggcgtcccggttggcgtcagctttgaggag
ctgtgtttgtccaaccctcgtttggtgcatgaagttcatacgtcttattaccaggccggt
gcgcgtttcctagagacaaatacgtattctgccaaccgagatgcattgagccgttacggt
ctggagcataaggtagccaggattaaccggctcgcagtcgccattgcacgggaagccgca
caggacgacgcttatgtggctggaagcatcggatcgattttggcaggacgggtgaagaaa
aaggttttggatgaataccgtgaccagtatgaggaacaggccattgccctgttacatgcg
ggggtagacggactgattctggagacgttcttggacttggaggagctgcttctggcgatc
gaggtaatccgcccgctcacagatgtccctgtaatcgcgcagttagccactttggaagta
gggcgcacacgtgatggttacgctttgacagatgccttttccgagctgaaagcagcgggc
gctgacgtggtcggactaaactgtcgacttggtcccgctgaactcttgcgctcgtttgaa
aatacagtgattccagaagatgcactcctatccgtattcccgaatgcggggcgtctgggg
atgactgacggagaatacgcttttaaatcatcacctgaatactttggacaaagtgcgctt
cgcttgcgtgagcagggagttcggttgattggtggatgctgcggaaccacacctgcacat
gtgaaggcgattgcggatgcacttgaatctcttgaaccgcaagcgcgtgtgaacccgacc
atcgttgctggagatcgtcctacgatttctgtgcagaacacgagggagagggagaaacca
agcattgtcgagcgtgtaaaaacagcaacgacaatcattgtcgagtttgatccgccacgt
gatctggatgcagaccaatttctccacggatgctgtgagctgcacaaagcaggagcagac
gcgattacgttggcggataactcgttggcgacagtgcgcatgagcaacatggctctcggt
gccctcatgaagagcagacatggaatcgatccgctcttgcaccttgcttgccgggatcgc
aatctgattggacagcaatcgcacttaatgggcctcaacgctttggggattgaccaaata
ttggtgattactggtgatccatcacgctttggtgacttgccaggggccagctcggtattt
gatgtgacctcgtttgatctgattcgcatggtgaagcagttgaacgaaggtgtttcgttc
tcaggacgtccgttaaagcaaaaagcccagtttatcgtgggcgctgcctttaatccgaat
gtccgaaatatggatgctgccgttgcccgcttggaaaagaaggtcgaggcaggcgcggat
tacattatgacgcagcctgtgtacgatgcggagtcgattcggaatgtatacgaggcgacg
aagcatattggcattcctgtctttatcgggatcatgccgctgaccagctcgcgcaatgcg
gagttcctgcataatgaagtgccgggaatcaagctatcgacagaagctctagaacggatg
aaaaaggtacagggagaagccgccagacaggaaggaatcgcaatcgcgaaggaattggtt
gatacggccgttcgttacttcaatggcatctatttgattacaccttttaattattacgag
atggcggcagagctcattcaatatacccgccaacaaagctctttggtgaggatggctcag
acgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (43)   

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