KEGG   Bubalus bubalis (water buffalo): 102392112
Entry
102392112         CDS       T05912                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor isoform X1
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub01523  Antifolate resistance
bbub04010  MAPK signaling pathway
bbub04060  Cytokine-cytokine receptor interaction
bbub04061  Viral protein interaction with cytokine and cytokine receptor
bbub04064  NF-kappa B signaling pathway
bbub04071  Sphingolipid signaling pathway
bbub04150  mTOR signaling pathway
bbub04210  Apoptosis
bbub04217  Necroptosis
bbub04350  TGF-beta signaling pathway
bbub04380  Osteoclast differentiation
bbub04612  Antigen processing and presentation
bbub04620  Toll-like receptor signaling pathway
bbub04621  NOD-like receptor signaling pathway
bbub04622  RIG-I-like receptor signaling pathway
bbub04625  C-type lectin receptor signaling pathway
bbub04640  Hematopoietic cell lineage
bbub04650  Natural killer cell mediated cytotoxicity
bbub04657  IL-17 signaling pathway
bbub04660  T cell receptor signaling pathway
bbub04664  Fc epsilon RI signaling pathway
bbub04668  TNF signaling pathway
bbub04920  Adipocytokine signaling pathway
bbub04930  Type II diabetes mellitus
bbub04931  Insulin resistance
bbub04932  Non-alcoholic fatty liver disease
bbub04933  AGE-RAGE signaling pathway in diabetic complications
bbub04936  Alcoholic liver disease
bbub04940  Type I diabetes mellitus
bbub05010  Alzheimer disease
bbub05014  Amyotrophic lateral sclerosis
bbub05020  Prion disease
bbub05022  Pathways of neurodegeneration - multiple diseases
bbub05132  Salmonella infection
bbub05133  Pertussis
bbub05134  Legionellosis
bbub05135  Yersinia infection
bbub05140  Leishmaniasis
bbub05142  Chagas disease
bbub05143  African trypanosomiasis
bbub05144  Malaria
bbub05145  Toxoplasmosis
bbub05146  Amoebiasis
bbub05152  Tuberculosis
bbub05160  Hepatitis C
bbub05161  Hepatitis B
bbub05163  Human cytomegalovirus infection
bbub05164  Influenza A
bbub05165  Human papillomavirus infection
bbub05166  Human T-cell leukemia virus 1 infection
bbub05168  Herpes simplex virus 1 infection
bbub05169  Epstein-Barr virus infection
bbub05170  Human immunodeficiency virus 1 infection
bbub05171  Coronavirus disease - COVID-19
bbub05205  Proteoglycans in cancer
bbub05310  Asthma
bbub05321  Inflammatory bowel disease
bbub05322  Systemic lupus erythematosus
bbub05323  Rheumatoid arthritis
bbub05330  Allograft rejection
bbub05332  Graft-versus-host disease
bbub05410  Hypertrophic cardiomyopathy
bbub05414  Dilated cardiomyopathy
bbub05417  Lipid and atherosclerosis
bbub05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102392112 (TNF)
   04350 TGF-beta signaling pathway
    102392112 (TNF)
   04064 NF-kappa B signaling pathway
    102392112 (TNF)
   04668 TNF signaling pathway
    102392112 (TNF)
   04071 Sphingolipid signaling pathway
    102392112 (TNF)
   04150 mTOR signaling pathway
    102392112 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102392112 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    102392112 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    102392112 (TNF)
   04217 Necroptosis
    102392112 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102392112 (TNF)
   04620 Toll-like receptor signaling pathway
    102392112 (TNF)
   04621 NOD-like receptor signaling pathway
    102392112 (TNF)
   04622 RIG-I-like receptor signaling pathway
    102392112 (TNF)
   04625 C-type lectin receptor signaling pathway
    102392112 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    102392112 (TNF)
   04612 Antigen processing and presentation
    102392112 (TNF)
   04660 T cell receptor signaling pathway
    102392112 (TNF)
   04657 IL-17 signaling pathway
    102392112 (TNF)
   04664 Fc epsilon RI signaling pathway
    102392112 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    102392112 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102392112 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102392112 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102392112 (TNF)
   05170 Human immunodeficiency virus 1 infection
    102392112 (TNF)
   05161 Hepatitis B
    102392112 (TNF)
   05160 Hepatitis C
    102392112 (TNF)
   05171 Coronavirus disease - COVID-19
    102392112 (TNF)
   05164 Influenza A
    102392112 (TNF)
   05168 Herpes simplex virus 1 infection
    102392112 (TNF)
   05163 Human cytomegalovirus infection
    102392112 (TNF)
   05169 Epstein-Barr virus infection
    102392112 (TNF)
   05165 Human papillomavirus infection
    102392112 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102392112 (TNF)
   05135 Yersinia infection
    102392112 (TNF)
   05133 Pertussis
    102392112 (TNF)
   05134 Legionellosis
    102392112 (TNF)
   05152 Tuberculosis
    102392112 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102392112 (TNF)
   05144 Malaria
    102392112 (TNF)
   05145 Toxoplasmosis
    102392112 (TNF)
   05140 Leishmaniasis
    102392112 (TNF)
   05142 Chagas disease
    102392112 (TNF)
   05143 African trypanosomiasis
    102392112 (TNF)
  09163 Immune disease
   05310 Asthma
    102392112 (TNF)
   05322 Systemic lupus erythematosus
    102392112 (TNF)
   05323 Rheumatoid arthritis
    102392112 (TNF)
   05321 Inflammatory bowel disease
    102392112 (TNF)
   05330 Allograft rejection
    102392112 (TNF)
   05332 Graft-versus-host disease
    102392112 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102392112 (TNF)
   05014 Amyotrophic lateral sclerosis
    102392112 (TNF)
   05020 Prion disease
    102392112 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    102392112 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102392112 (TNF)
   05418 Fluid shear stress and atherosclerosis
    102392112 (TNF)
   05410 Hypertrophic cardiomyopathy
    102392112 (TNF)
   05414 Dilated cardiomyopathy
    102392112 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102392112 (TNF)
   04940 Type I diabetes mellitus
    102392112 (TNF)
   04936 Alcoholic liver disease
    102392112 (TNF)
   04932 Non-alcoholic fatty liver disease
    102392112 (TNF)
   04931 Insulin resistance
    102392112 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102392112 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102392112 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bbub04052]
    102392112 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:bbub00536]
    102392112 (TNF)
Cytokines and neuropeptides [BR:bbub04052]
 Cytokines
  Tumor necrosis fators
   102392112 (TNF)
Glycosaminoglycan binding proteins [BR:bbub00536]
 Heparan sulfate / Heparin
  Cytokines
   102392112 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 102392112
NCBI-ProteinID: XP_006041992
EnsemblRapid: ENSBBUG00015014208
UniProt: Q2MH01
Position
2:24719931..24722721
AA seq 234 aa
MSTKSMIRDVELAEEVLSEKAGGPQGSRSCLCLSLFSFLLVAGATTLFCLLHFGVIGPQR
EEQSPGGPSINSPLVQTLRSSSQASSNKPVAHVVADINSPGQLRWWDSYANALMANGVKL
EDNQLVVPADGLYLIYSQVLFRGQGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHR
ETPEWAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPDYLDYAESGQVYFGIIAL
NT seq 705 nt   +upstreamnt  +downstreamnt
atgagcaccaaaagcatgatccgggatgtggagctggcggaggaggtgctctccgagaaa
gcagggggcccccagggctccagaagttgcttgtgcctcagcctcttctccttcctcctg
gttgcaggagccaccacgctcttctgcctgctgcacttcggggtaatcggcccccagagg
gaagagcagtccccaggtggcccctccatcaacagccctctggttcagacactcaggtcc
tcttctcaagcctcaagtaacaagccggtagcccacgttgtagccgacatcaactctccg
gggcagctccggtggtgggactcatatgccaatgccctcatggccaacggcgtgaagcta
gaagacaaccagctggtggtgcctgctgacgggctttacctcatctactcacaggtcctc
ttcaggggccaaggctgcccttccacccccttgttcctcacccacaccatcagccgcatt
gcagtctcctaccagaccaaggtcaacatcctgtctgccatcaagagcccttgccacagg
gagaccccagagtgggctgaggccaagccctggtacgaacccatctaccagggaggggtc
ttccagctggagaagggagatcgcctcagtgctgagatcaacctgccggactacctggac
tatgctgagtctgggcaggtctactttgggatcatcgccctgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (65)   
   KEGG PATHWAY (65)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (1)   
   Pfam (1)   
All databases (91)   

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