KEGG   Bubalus bubalis (water buffalo): 102412917
Entry
102412917         CDS       T05912                                 
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2
  KO
K12405  (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub00120  Primary bile acid biosynthesis
bbub01040  Biosynthesis of unsaturated fatty acids
bbub01100  Metabolic pathways
bbub01212  Fatty acid metabolism
bbub04146  Peroxisome
Module
bbub_M00861  beta-Oxidation, peroxisome, VLCFA
bbub_M00862  beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    102412917 (HSD17B4)
   01040 Biosynthesis of unsaturated fatty acids
    102412917 (HSD17B4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    102412917 (HSD17B4)
Enzymes [BR:bbub01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.107  3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
     102412917 (HSD17B4)
    4.2.1.119  enoyl-CoA hydratase 2
     102412917 (HSD17B4)
SSDB
Motif
Pfam: MaoC_dehydratas adh_short adh_short_C2 SCP2 KR Alkyl_sulf_C MaoC_dehydrat_N AbrB-like FAS_pseudo-KR HerA_C Epimerase 3HCDH_N
Other DBs
NCBI-GeneID: 102412917
NCBI-ProteinID: XP_006078158
EnsemblRapid: ENSBBUG00015003979
Position
9:76740389..76838677
AA seq 736 aa
MASMLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFTGVGKGSLAADKVVE
EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDIIQ
RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYCAAKLGLLGLSNCLAV
EGKKNNIHCNTIAPTAGSRMTESILPEDLLEALKPDYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLQWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN
KINSGGEVSANPTSRATSAATSEFAGAIGHKLPPFYSSYAELDTIMYALGVGASIKEPKD
MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELYKPLPRA
GKLRCETIVADILDKGSGLVILMDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA
AVAIPDRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN
AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGVGQEVVKKVGAVFEWHITKGENT
AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
LLSQKLQMILKDYAKL
NT seq 2211 nt   +upstreamnt  +downstreamnt
atggcctcgatgttgaggttcaacgggagggtggtactggttaccggcgcggggggagga
ttgggccgagcctatgccctggcttttgcagaaagaggtgcatcagttgttgtgaatgac
ctaggaggggacttcacaggagttggcaaaggctccttagctgctgataaggttgttgaa
gaaataagaaggaaaggtggaaaagcagtggctaactatgattcagtggaagaaggggag
aagattgtgaagacagcactggatgcttttggaagaatagatattgtgatcaacaatgct
gggattctgagggaccgttcatttagtagaataagtgatgaagactgggacataatccag
agagttcatttgcggggctcattcctggtgacccgggcagcatgggatcacatgaagaaa
cagaagtttggaagaatcatcatgacatcatcagcttcaggaatatatggcaactttggc
caagcaaattattgtgctgcaaaactgggtcttctgggcctttcgaactgtcttgcagtg
gaaggcaagaaaaacaacattcactgtaacactattgcccctactgctggatcacggatg
accgaaagcattttgcctgaagatcttctggaagccctaaagccggattacgtggcaccc
ctggtcctttggctttgccatgagagttgtgaagaaaacggtggcttgtttgaggttgga
gcaggatggattggaaaattacaatgggagcgaagccttggagcccttgtgagacagagg
actcagccaatgactcctgaggcagtgaaggctaactggacgaagatctgtgatttcgat
aatgccaccaagcctaagagtattcaagagtccattggcagtatagtcgaagctctaaat
aaaataaattcaggtggagaagtttcagcaaatcctaccagccgtgcaacatcagcagcc
acgtctgaatttgctggagctattggtcataaacttcctccattttattcttcttatgcg
gagctggacactattatgtatgcccttggagtgggagcatcaatcaaggagccaaaagat
atgaaatttatttatgaagggagttctgatttctcctgtttgccaacctttggagttatt
cttgctcagaaatctataatgaatggaggattagcagagattcctgggctttcaatcaac
ttagcaaagattcttcatggggagcagtacttggagttatataaaccacttcccagagca
ggaaaattaagatgtgaaacaattgttgctgatatcctggataaaggatccggtttagta
attcttatggatgtctacacttactctggggaggaacttatatgttataatcagttctcc
atctttgttgttggttctggaggctctggtggaaaacggacatcagacaaagccaaggca
gctgtagccatacccgatagacctcctgatgctgtacttacagataccacctcacttaat
caggctgctttgtaccgcctcagtggagattggaatcccttacacattgatcctaacttt
gctagcttagcaggtttcgataagcctatattacatggattatgtacatttggattttct
gccaggcatgttttacagcagtttgcagataatgatgtatcgagattcaaggcaattaag
gttcgttttgcaaaaccagtatacccgggacagactctgcagactgagatgtggaaggaa
ggaaatagaatccatttccaaaccaaggtccaagaaactggaggcatcgtcatttcaaat
gcatatgtggatcttgtgccagcgtctgctatttcagctaagacaccatctgagggtgcg
gggcttcagagtactcttgtgtttgaagaaataggtcgccgccttcagggtgttgggcaa
gaggtggtgaagaaagtcggtgctgtgtttgagtggcatatcactaaaggtgaaaatact
gcagccaagtggactattgacctgaaaactggttctggaaaagtgtatcaaggccctgca
aaaggctctgctgatgtaaccatcacactttcagatgaagatttcatggaagtagtcttg
ggcaagcttgatcctcagaaggcgttctttagtggcagactgaaggccagagggaatatc
ttgctgagccagaagctccagatgattcttaaagactatgccaagctctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (5)   
   KEGG MODULE (3)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (12)   
   Pfam (12)   
All databases (64)   

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