KEGG   Alkalihalobacillus clausii: ABC0422
Entry
ABC0422           CDS       T00228                                 
Symbol
iolA
Name
(GenBank) methylmalonate-semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
bcl  Alkalihalobacillus clausii
Pathway
bcl00280  Valine, leucine and isoleucine degradation
bcl00410  beta-Alanine metabolism
bcl00562  Inositol phosphate metabolism
bcl00640  Propanoate metabolism
bcl01100  Metabolic pathways
bcl01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:bcl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    ABC0422 (iolA)
   00562 Inositol phosphate metabolism
    ABC0422 (iolA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    ABC0422 (iolA)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    ABC0422 (iolA)
Enzymes [BR:bcl01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     ABC0422 (iolA)
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     ABC0422 (iolA)
SSDB
Motif
Pfam: Aldedh
Other DBs
NCBI-ProteinID: BAD62964
UniProt: Q5WKZ1
Position
469898..471373
AA seq 491 aa
MGETTVEVRKVKNYINGKWIESSTSLYEDVVNPATKEVICQVPLSTKADVEYAVEAAKTA
FAKWSKVAVPRRARILFNYQQLLQRDKEELARLITIENGKNLTEARGEVQRGIENVEFAA
GAPSLMMGDSLPMIATDVEASNYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNAFLLK
PSERTPLLTEKLADLLTEAGVPDGVFNVVYGAHDVVNGMLEHPDIKAISFVGSKPVGEYV
YKKASENLKRVQALTGAKNHTIVLNDADLDDAVTNIAGAAFGSAGERCMACAVVTVEEGI
ADAFVAKLKAKAESLVMGNGLDDGVFLGPVIREENKNRTIAYIEKGVEEGATLVCDGRSR
VSADGYFIGPTIFENVTTDMTIWKDEIFAPVLSIIRVKNLDEGIQIANRSEFANGACLFT
TNAAAVRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFYGTLHANGKDSVDFYTRKKV
VTARYPKPSFD
NT seq 1476 nt   +upstreamnt  +downstreamnt
atgggcgaaacaacagtagaggtccgtaaagtcaaaaattatattaatggtaaatggatt
gaaagcagcacaagcctttatgaagatgtagtgaatccggcgactaaagaagtcatttgc
caagtacccctttcgacaaaggcggatgtagagtacgcagttgaagccgcaaaaaccgct
tttgctaaatggtcgaaagtcgctgtgccgcgtcgtgcacggattttattcaattatcag
caactattgcagcgtgataaggaagaattggcgcgtttgattacaattgaaaacggcaaa
aacttgacggaagcacggggggaagtgcagcgtggcattgaaaatgttgaatttgctgca
ggtgccccgagcttaatgatgggcgattcattaccgatgattgcgacagacgtagaagca
agcaattatcgttaccccattggcgtcgtcggcggaatcgcgccattcaattttccgatg
atggtgccatgttggatgttcccaatggcgatcgcactcggaaatgcatttctattaaaa
ccttcagagcggacgccattattgactgaaaaactcgccgacttacttactgaagctgga
gtgccagatggcgtcttcaatgttgtctatggcgcccatgatgtcgtcaatggcatgcta
gagcaccctgacataaaagcgatatcgtttgtcggctctaagcctgttggcgagtatgtt
tataaaaaagcaagcgaaaacttaaaacgcgttcaagcgttgacaggagcaaaaaaccat
acaatcgtcttaaatgatgccgatttggacgacgccgtcaccaatattgccggagctgct
tttggctctgctggggagcgatgcatggcctgtgctgttgtaacagttgaggaaggaatt
gccgatgcgtttgtagccaaattaaaggcaaaagctgaatcgctcgtaatgggcaatggt
ttagacgacggtgtgtttttaggccctgtcatacgtgaagaaaacaaaaaccgaaccatt
gcttatattgaaaaaggagtggaggaaggggcgacccttgtatgcgacggccgaagccga
gtatctgccgatggttattttattgggccgacgatttttgaaaatgtgacaacggatatg
acaatttggaaagatgaaatttttgcccctgtgctttcgattatccgtgtgaaaaattta
gatgaggggattcaaatagccaatcgttctgaatttgcaaacggagcttgcctatttaca
acgaatgcggcggccgttcgctattttcgtgaaaacattgatgctggaatgcttggcatt
aaccttggtgttcctgcacctatggcattttttcctttttcaggatggaaatcgtcgttt
tatgggacgcttcatgcaaacggaaaagatagcgtagacttttatacgcgcaaaaaagtc
gtgaccgcccgttatccgaagccgtcatttgactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (1)   
   Pfam (1)   
All databases (34)   

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