KEGG   Bos indicus (zebu cattle): 109553155
Entry
109553155         CDS       T04792                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu00562  Inositol phosphate metabolism
biu01100  Metabolic pathways
biu04014  Ras signaling pathway
biu04015  Rap1 signaling pathway
biu04020  Calcium signaling pathway
biu04024  cAMP signaling pathway
biu04070  Phosphatidylinositol signaling system
biu04919  Thyroid hormone signaling pathway
biu04933  AGE-RAGE signaling pathway in diabetic complications
biu05205  Proteoglycans in cancer
Module
biu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:biu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    109553155 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    109553155 (PLCE1)
   04015 Rap1 signaling pathway
    109553155 (PLCE1)
   04020 Calcium signaling pathway
    109553155 (PLCE1)
   04070 Phosphatidylinositol signaling system
    109553155 (PLCE1)
   04024 cAMP signaling pathway
    109553155 (PLCE1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    109553155 (PLCE1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109553155 (PLCE1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    109553155 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:biu04131]
    109553155 (PLCE1)
Enzymes [BR:biu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     109553155 (PLCE1)
Membrane trafficking [BR:biu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    109553155 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    109553155 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 109553155
NCBI-ProteinID: XP_019808669
UniProt: A0A6P5BH55
Position
26:15919461..16330764
AA seq 2297 aa
MTSEEMAGSVLRPVSQRKVISAQSTVDESNDKVSGISVPKSHPVRQSGETSHTISQPTKL
TEESSGSNAPQIFSVAREKITSDENSNEKCWEKSMPDSVKNLNINCNSILKNHQHGPPQS
QFYETCNSITEEGLCLETGIPSSLEGKVFPGIQLEIDTSPMGMSPLGTQSAIIETSRAHP
ESNMAVFHLRYEVDRRMSDSFCPLSDNLILDDCGNCVLPAVGEEQEKNYMAYTCKLMELT
NNCDNKNRQLQCDHCDPLNDKYLCFEGSCPKANVVCSSDSFCREDFTDSPPAKTFLSHFE
DFPDNCEEVEEELFKNKKERSAWLVRRFCKNDKEVKKSVFTGTRAIVRTLPSGHIGLEAL
SYIDQKKNGLLLPPGRVMERLSTVVVRQDGSQGLSEAQWYPIYSAVRRGEATEQTIRSLL
HFFAKLPASETAHERISVGPYLKQCVRDTVCEYRATLQRTSISQYITGSLLEATXSLGAR
SSLLNSFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLKPLIQFPEEVASILM
EQEQNIYRRVLPVDYLFFLTRGLGTTERQRSLPCLKASISASILTSQKGEHNALEDLVMR
FNEVSSWVTWLILAAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRS
LETEEEDSSSEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDSHGSEEPQKAFD
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTAS
PASAKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGILDLFSAKAVYMGHPNIDIHTVCVQN
KLSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
HWLRKQYVSLYQEDGRYEGPTLAQAVELFGGRRWSTRNPSPGTSAKSAEKPNTLSISNTK
KKKKILMRGESGEVTDDEMATRKARTHKESRSRSGSDPQDVNEQEESEANAIMNPPNPLP
SRRAHSLTTTGPPTLAAGTASPIRPVSSPVLPASNRSPTSAWNSSSGWPGKIKGGMQGFQ
SFMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSEAAPLYTNLTIDENI
SGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGV
GILQLNDFLVNCQGEHYTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASKN
DESQENVKEMQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTV
FGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QAYNGSNAXSPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIP
KRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLN
ASGSSRGKERKSRKSIFGNNPGRMSPGETAPFNKTSGKSSCEGMRQAWEDSAFSVNPTTS
LSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLLF
WLHGIQLVALNYQTDDLSLHLNAAMFEANGGCGYVLKPPVLWDKNCSMYQKFSPLERDLD
SMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMALDSCHFRTKPIHRNTLNPMWNEQF
LFRVHFEDLXFLRFAVVENNSSVVTAQRIISLKALKRGYRHLQLRNLHNEVLEISSLFIN
SRRMEENSSGNTVLASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQQ
ILVMDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGYV
GRIVLKTQQENLEEKSIAQDDKEMLLSSEEDSFFVQVHDVSPEQPRTVIKAPRVSTAQDV
IQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANRKSSTPKASQRVLLDQECVFQAQSK
WKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKTKQPRGPTSPSQVLASENVQNKE
EKPVGGLPSSDTIDYRQ
NT seq 6894 nt   +upstreamnt  +downstreamnt
atgacttctgaagaaatggcaggttctgttctcagacctgtgagtcagagaaaagtgatc
tctgctcagtcaactgtagatgaaagtaatgataaggtctcgggcatcagtgttccgaag
tctcatcctgtcaggcagagtggggagacttctcataccatctcgcaaccgaccaaactt
acagaagaatcttctggaagcaacgcgccccagattttctcagtagcaagggagaaaata
accagtgacgagaacagtaatgaaaagtgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacagcatattgaaaaaccatcagcacggccctcctcagagc
cagttttatgaaacgtgcaattctatcacagaggaaggtctgtgtttggaaactggaatc
ccttcttcactggaaggaaaggtgttccctggaattcaactggaaatagacacatctccc
atgggcatgagtccattaggaactcagtcggccatcatagagacaagcagggcacaccct
gaaagcaacatggcagtgtttcacttgcgttacgaagttgacagaagaatgtcagacagt
ttctgtcccctgtcagataacttgattttggatgattgtggaaactgtgtactacctgcc
gttggtgaggaacaagagaaaaattacatggcatatacttgcaaactgatggaattgaca
aataactgtgacaataagaataggcagctgcagtgtgatcattgtgaccccttgaatgac
aaatacttgtgctttgaaggctcttgcccaaaggccaatgtggtatgttcaagtgacagc
ttttgcagggaggattttactgacagtccacctgccaagacctttctgagccattttgag
gacttccccgataattgtgaagaggtagaagaagaattgttcaaaaataaaaaggagcgg
tctgcttggttagtgaggagattttgcaaaaatgacaaggaagttaagaaatctgtgttt
actgggacaagggcaattgtgagaactttgccytctggtcacattggactggaggctttg
agttacattgatcagaagaaaaatggtctcttattgcctcctgggagagtcatggaacgg
ctgtcaacagtggtggttaggcaagatggttcccaaggtctgtcagaagcccagtggtat
ccgatctacagtgcagtgagaaggggagaagccacagaacagacaattagatctcttctc
catttcttcgccaagctcccagcctccgagacagcccatgagaggatcagtgtcggtccg
tacttaaagcaatgtgtccgagacacrgtgtgtgagtatcgtgccaccttgcaaaggact
tccatatctcagtayatcaccggctctctcctggaagccaccayatctttaggagcaaga
agcagcctcctcaattcttttggaggatccacgggacgaatgatgctgaaagaacgccaa
ccaggcacctctatggccaactccagtgcccttccttcaagttcagctgggatcagcaag
gaactgattgatctgaagcccctcatccagttcccagaggaagtcgccagcatcctgatg
gagcaggagcaaaatatttaccgaagggtcttgccagttgactatcttttcttcttgacc
cggggcttgggcacaacagaacgccagaggtccctgccctgcctcaaagcatccatctca
gcatccattcttacctcccagaagggagagcacaaygccctcgaagatcttgtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcgcggcgggctccatggaagag
aagcgggaagtcttctcatacttggttcatgtggccaaatgctgctggaacatgggcaac
tacaatgccgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgatctggagaccatgaggagcctgaaggatgccatggcccag
cacgagtcttcctgcgagtacaggaaggtggtgacccgagcgctgcacatccccggctgc
aaggtggttcccttctgcggggtgtttctgaaggagctctgtgaggtgctggacggagcc
tctggcctcatgaagctttgcccgaggtacaattcgcaggaagaaactctggagtttgta
gccgattatagtggacaagataatttcttacaacgagtgggacagaatggcttaaagaat
tcagagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagt
ctggagacagaggaggaggacagctccagtgaagggagcagctcaaggaaaaattccctg
aaggataaagcccgatggcagtttataatcggagatttgttggattctgaaaatgacatc
tttgagcagcccaaagagtgggactctcatggatcggaggagccacagaaagcctttgac
catgggacagagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccagttc
ctgttgcagggggccacggtcatccactatgatcaggacacgcacctctctgcccgctgc
ttcctccagcttcagcctgacaatagcaccttgacctggataaaacccaccactgcttcc
ccagccagtgctaaagcaaaacttggtgtgctcagtaacacgtctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggtggaggggatcttggatctgttttca
gcaaaggctgtgtacatgggacaccctaacattgatatacacactgtgtgtgttcagaac
aaactgagtaacatgtctctctcagagactggcgtgacactgctctacgggctgcagacc
acggacaatagattactgcactttgtggcgccaaagcacacagctaaaatgctcttcagt
ggattgttggagctcacgagagctgtgaggaagatgaggaagttccctgaccaaagacag
cattggctgcggaaacagtacgtcagcctctaccaggaggatggacgatatgaaggccca
actttggctcaagctgtagagctgtttggtggcagacgatggagtactcgaaaccccagc
cctgggacatcagcaaagagcgctgagaagcccaacaccttgagtataagcaacaccaag
aaaaagaagaaaatccttatgaggggtgagagtggagaggtgacggatgatgagatggcc
acccgcaaggccagaacacacaaagagagccggagccggagcggctctgatcctcaagat
gtcaatgaacaagaagaatcagaggcaaatgccatcatgaaccctcccaaccctctccct
tccagaagagcccactccttgaccacgactgggccccctaccttggctgccgggacagca
tctcccatcaggccagtgtcctctcctgtgctgcctgcttccaacaggagcccaaccagt
gcttggaacagcagcagcggctggccagggaagatcaaaggagggatgcagggctttcag
agcttcatggtttcagacagcagcatgagtttcgtggaatttgttgagctgttcaagtca
ttcagtgtgaggagccgcaaggacctgaaggacctctttgacatctacgccgtaccctgt
gaccgagctggctctgaggcagcccccctctataccaacctgaccattgacgaaaatatc
agcggtcttcagcctgacctagatttgttgaccagaaatgtctcagatttgggattattc
atcaagagtaaacagcagctgtctgacaaccagaggcagatatctgatgccattgctgct
gccagtattgtgacaaatggcactggggtggagagcacatctctgggtgtgtttggagtt
ggtatcctccagctcaatgacttcctagtgaattgccaaggagaacactatacttatgac
gaaatcctcagcattatccagaagttcgagcctagcgttagtatgtgtcatcaaggccta
atgtcatttgaaggatttgcaaggtttctaatggataaagataattttgcctcgaaaaat
gatgagtcacaggagaacgttaaagaaatgcagctgcccctctcctactattacattgaa
tcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaactc
tacagccaggtcctcctgcaaggctgtaggagtgtagagttggactgctgggacggagat
gatggaatgcccatcatttatcatggacacaccctgacaaccaagatccccttcaaggaa
gtggttgaagccatcgatcgcagtgccttcatcaactctgacctacccatcatcatatcg
attgagaaccactgytcattgcctcagcaacgaaaaatggcagaaattttcaagactgtg
tttggagaaaaactggtggctaaattcttatttgagagtgatttctcagatgatcctatg
ctcccctcacctgaccaactcagaaggaaagtgcttctcaaaaataagaaattaaaagcc
catcagacaccggtggatatcttaaagcaaaaggctcatcagctagcatccatgcaagct
caggcttataatggtagcaatgccarctccccacctgctaataatgaggaagargaagat
gaagaggatgaatatgattatgattatgaatccctctctgatgacaacattctagaagac
agacctgaaaataaatcatgtaatgacaaacttcagtttgagtataatgaagaaatcccc
aagaggataaagaaagcagataactctgcttgcaacaaagggaaggtttatgacatggaa
ctgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagag
ctttctgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactctaaat
gcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaat
ccgggcagaatgagccccggggagacagcaccatttaacaaaacatctggaaaaagttcc
tgtgaaggaatgcgacaggcctgggaggactctgctttctccgtcaacccaaccacgtcc
ctcagcgctatcattagaactcccaaatgctaccatatctcctcactgaatgaaaatgcc
gccaaacgtctgtgtcgcaggtattctcagaaactcatccagcacaccgcctgccagcts
ctgcggacgtacccggctgccacccgcatcgactcytccaaccccaaccccctcctgttc
tggctccatgggatacagctcgtggcgctcaactaccagacagatgatctctctttacat
ttaaatgccgccatgtttgaggccaatggtggctgcggttatgttctgaaacccccagtt
ctgtgggacaagaactgttcyatgtatcagaagttctcccccttggaaagagacctggac
agcatggagcctgccatctattctttaactattgtctctgggcagaacgtgtgcccgagt
aacagcacggggagcccatgtatcgaagtcgatgtcctgggcatggccctggacagctgc
cacttccgcacgaagcccatccaccgcaatactctgaaccccatgtggaacgaacagttt
cttttccgggttcacttcgaagatctcrtatttcttcgttttgctgtcgtggagaacaac
agctcggtggtcactgctcagagaatcatctccctcaaggctctaaagcgaggatatcga
catcttcagctgagaaatctccacaatgaagtcttggaaatctctagtttattcataaac
agcaggaggatggaagaaaattcttccggcaatactgtgctggcctctctgatgtttaat
acggaagaaagaaaatgtttgcagactcacagagtcacagtgcatggcgtcccaggccca
gagccctttactgttttctctataaacggaggcactaaggcaaagcagcttctccaacaa
attctcgttatggatcaagataccaaacctattgccacagattattttttaatggaggaa
aaatatttcatatctaaagagaagaatgaatgtaggaaacagccgttccagagagccatt
ggtccagaagaagagatcgtgcagattttaagcagctggtttccagaagagggctatgtt
ggcaggattgtcttaaaaacccagcaggaaaacctggaagagaagagcattgcacaagat
gacaaggagatgctcctgagctcagaggaggacagcttctttgtccaggtgcatgacgtt
tccccagagcaaccacgcacggtcatcaaggcgccgcgtgtcagcaccgcgcaggatgtc
attcagcagaccttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccr
agtgactatgtgcttttggaagaggtggtgaaagacaccgccaacaggaaatcttccacc
ccaaaggcctcccagcgcgtccttttggatcaggagtgtgtgtttcaagctcaaagcaag
tggaaaggtgcaggaaaattcatccttaagctaaaggaacaggtgcaggcatctcgagaa
gataaaaaaaaaggcatctcttttgcaagcgaactcaagaagctcaccaagactaaacag
ccccgaggacccacatcaccttctcaggtcttggcctcagaaaacgtccaaaacaaggaa
gagaaacctgtgggtggcttgccttccagtgacaccatagactaccgacagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (43)   

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