KEGG   Bos indicus (zebu cattle): 109560300
Entry
109560300         CDS       T04792                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu04010  MAPK signaling pathway
biu04020  Calcium signaling pathway
biu04022  cGMP-PKG signaling pathway
biu04114  Oocyte meiosis
biu04218  Cellular senescence
biu04310  Wnt signaling pathway
biu04360  Axon guidance
biu04370  VEGF signaling pathway
biu04380  Osteoclast differentiation
biu04625  C-type lectin receptor signaling pathway
biu04650  Natural killer cell mediated cytotoxicity
biu04658  Th1 and Th2 cell differentiation
biu04659  Th17 cell differentiation
biu04660  T cell receptor signaling pathway
biu04662  B cell receptor signaling pathway
biu04720  Long-term potentiation
biu04724  Glutamatergic synapse
biu04728  Dopaminergic synapse
biu04921  Oxytocin signaling pathway
biu04922  Glucagon signaling pathway
biu04924  Renin secretion
biu05010  Alzheimer disease
biu05014  Amyotrophic lateral sclerosis
biu05020  Prion disease
biu05022  Pathways of neurodegeneration - multiple diseases
biu05031  Amphetamine addiction
biu05152  Tuberculosis
biu05163  Human cytomegalovirus infection
biu05166  Human T-cell leukemia virus 1 infection
biu05167  Kaposi sarcoma-associated herpesvirus infection
biu05170  Human immunodeficiency virus 1 infection
biu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
biu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:biu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109560300 (PPP3CA)
   04310 Wnt signaling pathway
    109560300 (PPP3CA)
   04370 VEGF signaling pathway
    109560300 (PPP3CA)
   04020 Calcium signaling pathway
    109560300 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    109560300 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    109560300 (PPP3CA)
   04218 Cellular senescence
    109560300 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    109560300 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    109560300 (PPP3CA)
   04660 T cell receptor signaling pathway
    109560300 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    109560300 (PPP3CA)
   04659 Th17 cell differentiation
    109560300 (PPP3CA)
   04662 B cell receptor signaling pathway
    109560300 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    109560300 (PPP3CA)
   04921 Oxytocin signaling pathway
    109560300 (PPP3CA)
   04924 Renin secretion
    109560300 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    109560300 (PPP3CA)
   04728 Dopaminergic synapse
    109560300 (PPP3CA)
   04720 Long-term potentiation
    109560300 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    109560300 (PPP3CA)
   04380 Osteoclast differentiation
    109560300 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109560300 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109560300 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    109560300 (PPP3CA)
   05163 Human cytomegalovirus infection
    109560300 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109560300 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    109560300 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109560300 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    109560300 (PPP3CA)
   05020 Prion disease
    109560300 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    109560300 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    109560300 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109560300 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:biu01009]
    109560300 (PPP3CA)
Enzymes [BR:biu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     109560300 (PPP3CA)
Protein phosphatases and associated proteins [BR:biu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     109560300 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 109560300
NCBI-ProteinID: XP_019817946
UniProt: A0A6P5BXA0
Position
6:25108244..25433988
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEETV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacggcaaaagaagtgtttgataatgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctcgaagagactgtc
gcattgagaataataacagagggggcttcaattcttcgacaggaaaaaaacttgctggat
attgatgctccagtcacagtttgtggggacatccatggacaattctttgacttgatgaaa
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgcatggat
gcctttgactgcctgcccctggctgccctgatgaaccagcagttcctgtgtgtacacggc
ggtttgtctccagagataaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagacccgctggaagattttgga
aacgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttgcagcacaataacttgttatctatcctccgagct
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttcccc
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgttttcacctggtccctgccgtttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagacgatgaactagggtcagaa
gaagatggatttgatggagcaacggctgcagccaggaaggaggtgataagaaataagatc
cgagccattggcaagatggccagagtgttctcggttctcagagaagagagtgagagtgtg
ctgacgctgaaaggcctgacgcccacaggcatgctccccagcggcgtgctttctggaggg
aaacaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaay
gagaggatgccacctcgcagagatgccatgccctctgatgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatc
cagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (33)   
   KEGG PATHWAY (33)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (1)   
   Pfam (1)   
All databases (48)   

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