KEGG   Bos indicus (zebu cattle): 109564329
Entry
109564329         CDS       T04792                                 
Symbol
EIF2AK4
Name
(RefSeq) eIF-2-alpha kinase GCN2
  KO
K16196  eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu04140  Autophagy - animal
biu05160  Hepatitis C
biu05162  Measles
biu05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:biu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109564329 (EIF2AK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    109564329 (EIF2AK4)
   05162 Measles
    109564329 (EIF2AK4)
   05168 Herpes simplex virus 1 infection
    109564329 (EIF2AK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:biu01001]
    109564329 (EIF2AK4)
Enzymes [BR:biu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     109564329 (EIF2AK4)
Protein kinases [BR:biu01001]
 Serine/threonine kinases: Other
  PEK family [OT]
   109564329 (EIF2AK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RWD HGTP_anticodon2 tRNA-synt_His Kinase-like HGTP_anticodon AAA_23
Other DBs
NCBI-GeneID: 109564329
NCBI-ProteinID: XP_019823371
UniProt: A0A6P5CC59
Position
10:35494563..35591617
AA seq 1570 aa
MAXGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDARGRVKEPPEINLVLY
PQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEEVAKKHCGE
VMIFELAYYVQSFLCEHNKPPPKSFHEEMLERRAQEEQRRQLEAKRKEEEEQREILHEIQ
KRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSRKDPGGHRTAAILHGGSPDFVGNGKHR
TNSSGRSKRERQYSMCNSEDSPGSCEILYFSVGSPDQLMVHKGKCIGSDEQLGKLVYNAL
ETATGSFVLLHEWVLQWHKKMGPFLTSQEKEKIDKCKKQIQGAETEFSSLVKLSHPNIVR
YFAMNLKEQDDSIVVDILVEHTNGISLAAHLGHSGPIPVHQLRKYAAQLLSGLDYLHSNS
VVHKVLSALNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDSALPYKTGKKGD
IWRLGLLLLSLSQGQECEEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFIN
PQSKIPLLEQSPEDSGGQDYVETVIPSNQLPSAAFFSETQRQFSRYFIEFEELQLLGKGA
FGAVIKVQNKLDGCCYAVKRIPINPASRHFRRIKGEVTLLSRLHHENIVRYYNAWIERHE
RPACPATPPPNSGPQAQDGRALAQPAGDSDPDGPGSVEAAAPPPILSSSVEWSTSGERSA
STRFPXAGPDSSSDEDDDEEQGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNGKN
SCHESEPPATTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIHE
KGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFAADGKQDDTSGDHLIKSDPSGHLTG
MVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSP
KFPEDFDDGEHTKQGSFSIRTAKIQQHVCETIIRIFKRHGAVQLCTPLLLPRNRQIYEHN
EAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIERVFRPRKLDRFHPKELLEC
AFDIVTSTTNXSLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDK
LSQVYVILYDAVTEKLTRREVEAKFCNLSLSSSSLCRLYKFIEQKGELQDLTPTINSLIK
QKTGVAQLVKYGLKDLEEVVGLLKKFGIKLQVLINLGLVYKVQQHSGIIFQFVAFIRRRQ
RAISEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDKITTAVLNMEEPVTVSSCDL
LVVSVGQMSMSRAINLTQKLWSAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKEG
SHVKVKSFEKDRQTEKRVPESDLVDHVVQKLRTKVSDERTTREASDNLTVQNLKGSFSNA
SGLFEIHGATVVPIVSVVAPEKLSASTRRRYETQVQTRLQTSLANLHQKSSEIEILAVDL
PKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVCDEIYNIKVEKKVSVLFLYS
YRDDYYRILF
NT seq 4713 nt   +upstreamnt  +downstreamnt
atggcnnnnggccgcggggcccccggacgtggccgggacgagccaccggagagctacccg
caacgacaagaccacgagctgcaggccctggaggccatctatggcgccgacttccaggac
ctgcggccggacgcgcgcggacgggtcaaagagcctcctgaaatcaatttagttctgtac
cctcaaggcctgactggtgaagaagtgtacgtgaaagtggatttgagagtgaaatgccca
cccacctatccagatgtagtccctgaaatagaattaaagaatgccaaaggtctgtcaaat
gaaagtgttaatttgttaaagtcccgcctagaagaagtggccaaaaaacactgtggtgag
gtgatgatatttgaactggcttactatgtgcagtcatttctctgcgagcacaacaagccc
cctcccaagtcttttcatgaagaaatgctggaaaggcgagctcaggaggagcarcggagg
cagttagaggccaagcggaaagaggaagaggagcaacgtgaaatccttcatgagattcag
aaaaggaaagaagagataaaagaggagaaaaaaaggaaagaaatggccaagcaggaacgt
ttagaaatagctagtttgtcaaatcaagatcatacctctagaaaagacccaggaggacac
agaacagctgccattctacatggaggctctcctgacttcgtaggaaatggtaaacatcgg
accaactcctctggaaggtctaagcgagaacgtcagtattctatgtgtaatagcgaagat
tctcctggctcttgtgaaatcctgtatttctctgtgggtagtcctgatcagctcatggtg
cacaaagggaaatgtattggcagtgatgagcagcttggaaaattagtttacaatgctttg
gaaacagctactggcagctttgtcttgttgcatgagtgggtccttcaatggcacaaaaaa
atgggtccattccttaccagtcaagaaaaagagaagattgataagtgcaaaaagcagatt
caaggggcagaaacagaattcagctcactggtgaaactgagccatccaaacatagtacgc
tactttgcgatgaacctcaaagagcaagacgactccatcgtggtggatattttagtggag
cacactaatgggatctccctcgcagcccacctgggccactcaggccccatcccggtacat
cagcttcgcaagtatgcagctcagctcttgtcaggccttgattacttgcacagcaattcc
gtggtgcacaaggttctgagcgcattgaatgtcctggtggatgcagagggcaccgtcaag
attacggactacagcatttctaagcgcctggcagacatttgcaaggaggacgtgtttgag
cagacccgggttcgtttcagtgacagcgccctaccttataaaaccgggaagaaaggggat
atttggcgtctcggccttctgctgctctccctcagccaaggacaagagtgtgaagagtat
cccgtgaccatccctagtgacttaccagctgattttcaagattttctaaagaagtgtgtc
tgcttagatgacaaggaaagatggagtcctcagcagttgttaaaacacagctttataaat
cctcagtctaaaatacctttactggaacaaagtcccgaagattctggaggacaagattat
gtggagactgtcattcctagcaaccagctacccagtgctgcattcttcagtgagacccag
agacagttttcccgctatttcattgagtttgaagaattacagcttctcggcaaaggagct
tttggagccgtcatcaaggtgcagaacaagctrgacggctgctgctatgcggtgaagcgc
atccccatcaacccggcmagcaggcacttccgcaggatcaagggcgaggtgacgctgctg
tcgcgcctccaccatgagaacatcgtgcgttactacaatgcctggatcgagagacatgag
cggccggcgtgcccggcgactccacccccgaactcggggccccaggcccaggacggacga
gccttagcccagccagcgggcgacagcgacccggacggyccgggcagtgtggaggcggcc
gcgccgccgcccatcctcagcagctcggtggaatggagcacgtcaggygagcgctcggcc
agcacccgcttccccrccgccggcccagactccagcagcgacgaggacgacgacgaggag
cagggcgtcttctcacagtccttcctacctgcttcagattctgacagtgatatcatcttt
gacaatgaagatgagaacagtaaaagccagaatcaggatgaagattgcaatggaaagaac
agttgtcatgaaagtgagccaccagcaaccaccgaggctgtgcactacctctacatccag
atggagtactgtgagaagagcactttacgagacaccattgaccagggactgtatcgagac
accgtcaggctctggaggcttttccgagagattctggatggattggcttatatccatgag
aaaggaatgattcaccgagatttgaagcctgtcaacatttttttggattctgatgaccat
gtcaaaataggtgattttggtttggccaccgaccatctagcctttgctgctgacggcaaa
caagatgacacatcaggagatcacttgattaaatcagacccttcaggtcatttgactggg
atggttggcactgctttatatgtaagccctgaggtccaaggaagcaccaaatctgcatac
aaccagaaagtggatctcttcagcctggggattatcttctttgagatgtcctatcatccc
atggtcacagcctcagaaagaatctttgttctcaaccagctcagagatcccacttcgcct
aagtttccagaagacttcgatgatggggagcatacaaagcagggcagcttctccatccgc
acagccaagatacagcagcacgtgtgtgaaaccatcatccgcatcttcaaaagacaygga
gctgtccagttgtgtaccccactgctgcttccccgaaacagacaaatatatgagcacaac
gaagctgccttattcatggaccacagcgggatgctggtgatgctgcctttcgacctgcgg
gttccttttgcaagatatgtggcgagaaataatatattgaatttaaagcgatattgcata
gaacgtgtgttcagacctcgaaaattagaccgatttcatcccaaagaacttctggagtgt
gcatttgatattgttacctctactaccaacrgctcgctgcccaccgctgaaatcatctac
accatctacgaaatcatccaggagtttccagcacttcaggaaagaaattacagtatttac
ttgaaccataccatgttactgaaagcaatactcttacactgtgggatcccagaagataaa
ctcagccaagtctatgttattctgtatgatgctgtgacagaaaagctgacgaggagagaa
gtggaagctaaattttgtaatctatccttgtcgtcaagtagtctgtgtcgactctacaaa
tttattgagcagaagggagagctgcaagatctaaccccaaccataaattcattaataaaa
cagaaaacaggtgttgcccagttggtgaagtacggcttaaaagatctggaggaggtcgtt
ggactgttgaagaaatttggcataaagttacaggtcctgatcaatctgggcttggtttac
aaggtgcagcagcacagcggaatcatcttccagtttgtggcattcatcagacggaggcaa
agggctatatctgaaatcctcgcagctggtggtagatacgacctgctgattccccagttt
agaggaccacaggctctggggccagttcctactgccatcggggtcagcatagccatagac
aagataaccactgctgtcctcaacatggaagagcctgttacagtaagctcttgtgacctc
ctggttgtaagtgttggtcagatgtccatgtccagggccatcaacctaacccagaaactc
tggtcagctggaatcacagcagaaatcatgtatgactggtcacagtcccaagaggaatta
caagagtactgcagacatcatgaaatcacctatgtggcccttgtctcggataaagaagga
agccacgtcaaggtaaagtcttttgagaaggacaggcaaacagagaaacgtgtgccggag
tctgatctcgtggaccacgttgtacagaaactgaggactaaagtcagtgatgagaggact
accagagaagcttccgataatcttacagtacaaaatctgaagggatcattttctaatgct
tcaggtttgtttgaaatccatggagcaacggttgttcccattgtgagtgtggtcgcccca
gaaaagctgtcagccagcacccgacggcggtatgagactcaggtacaaacccgacttcag
acctcccttgccaacttacatcagaaaagcagtgaaattgaaattttggctgtggatcta
cccaaagaaacaatcttacagttcctgtcattagagtgggatgctgatgaacaggcattt
aacacaactgtgaagcagctgctgtcacgcctgccaaagcaaagatacctcaaattagtc
tgtgatgagatttataacatcaaagtagaaaaaaaggtgtctgtgctcttcctgtacagc
tacagagatgactactacagaatcttattttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (24)   

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