| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
biu Bos indicus (zebu cattle)
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| Pathway |
| biu04977 | Vitamin digestion and absorption |
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| Brite |
KEGG Orthology (KO) [BR:biu00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
109578115 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
109578115 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
109578115 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109578115 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109578115 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:biu02000]
109578115 (ABCC1)
Enzymes [BR:biu01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
109578115 (ABCC1)
Transporters [BR:biu02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
109578115 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
25:15441948..15548961
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| AA seq |
1590 aa
MVVVLLVVMLLMVMLLMVDDGDADASDKDGGADDDRYSDADGADESDHDVALNSTQAPGP
HSWGRPVYLGLCLCPQEWNVTWNTSNPDFTKCFQNTVLVWVPCSXLWVCFPFYFLYLSHH
DRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFWERSMGKLLAPVFLVSPTLLGITMLLA
TFLIQIERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDARVDVFRDVTFYIYFS
LVLIQLVLSCFSDRSPLFSETINDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKIVYSSKDPAKPKGSSKVDVNEEAEAL
IVKCPQKERDPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPE
WQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKDAGATNSITVKNATFTWARNDPPT
LHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNI
SLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIV
MSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGQPEDGLAGVGGPGKEVKQMENGM
LVTDTAGKQMQRQLSSSSSYSGDVSRXXXXXXXLRKPGPTEETWKLVEADKAQTGQVKLS
VYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGA
LGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELD
TVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLK
RLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAV
RLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAV
ERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGE
KVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFS
GSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLA
RALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLD
KGEIQEWGSPSDLLQQRGLFYSMAKDSGLV |
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| NT seq |
4773 nt +upstreamnt +downstreamnt
atggtggtggtgctgttggtggtcatgctgctgatggtgatgctgctgatggtggatgat
ggcgatgctgatgccagtgayaaagatggtggtgctgatgatgaccgctatagtgatgct
gatggtgctgatgaaagtgatcatgatgtagctttgaactctacgcaggcccctggtcca
cactcctgggggcgtcctgtttacctgggcctgtgtttgtgtccgcaggagtggaatgtc
acgtggaacaccagcaaccccgacttcaccaagtgctttcagaacaccgtcctcgtgtgg
gtgccttgctcttwcctctgggtctgcttccccttctacttcctctatctctcccaccat
gaccggggctacattcagatgacacatctcaacaaagccaagactgccttggggtttttg
ctatggatcgtctgctgggcagacctcttctactctttctgggaaagaagtatgggcaag
ctcctggccccagtgttcctggtcagcccaaccctcttgggcatcaccatgctgcttgct
acctttttaattcagatcgagagaaggaggggagtccagtcctcagggatcatgctcact
ttctggcttatagccctactgtgtgcccttgccatcctgagatccaaaatcatgactgcc
ttaaaagaggatgcccgagttgatgtctttcgcgacgtcaccttctacatttactttagc
cttgtgctgatccagctcgtgttgtcctgcttctccgaccgctcgcccctgttctccgaa
accatcaacgaccccaatccttgcccggaatccagtgcctccttcctttccaggatcacc
ttctggtggatcacagggatgatggtccagggctaccgccagcccctggagagcaccgac
ctctggtccctgaataaggaggacacgtcagaacaagttgtgcccgtcttggtaaagaac
tggaagaaggaatgtgccaagtccagaaagcagccggtgaagatcgtgtactcctccaag
gaccccgccaagcccaaaggragctccaaggtggatgtgaacgaggaggccgaggctctg
attgtcaagtgtccccagaaggagcgggacccgtccctgttcaaagtgttatacaagacc
ttcgggccctactttctcatgagcttcttgttcaaagctgtgcatgacctgatgatgttt
gccggcccagagatcttaaagttgctcatcaacttcgtgaacgacaagaaggccccggaa
tggcagggttacttctacacggcgctgctgttcatcagcgcctgcctgcagaccctggtg
ytgcaccagtacttccacatctgcttcgtcagcggcatgcgcatcaagackgccgtcatc
ggggccgtgtaccggaaggccctggtgatcaccaatgcagccagaaagtcctccacrgtc
ggggagatcgtcaacctcatgtccgtggacgcccagaggttcatggacctggccacatac
attaacatgatctggtcagcccctctgcaagtcatccttgccctctacctcctgtggctg
aacctgggcccctccgtcctggcgggggtggccgtgatggtcctcatggttcccctcaat
gctgtgatggccatgaagaccaagacgtaccaggtggcccacatgaagagcaaggacaat
cggattaagctgatgaacgaaattctcaacgggatcaaagtgctgaagctttatgcctgg
gagctggcattcaaagacaaggtgctggccatccggcaggaagagctgaaggtgctgaag
aaatctgcctacctggccgcygtggggaccttcacctgggtctgcacccctttcctggtg
gccctgtccacgtttgccgtctacgtgaccgtcgacgagaacaacatcctggatgcccag
aaggccttcgtgtccttggccttgttcaacatcctccgcttccccctgaatatcctcccc
atggtcatcagcagcattgtgcaggcgagcgtctccctgaagcgcctgagggtcttcctg
tcccacgaggacctggaccctgacagcatccagcgccggcccatcaaagacgctggagcc
acgaacagcatcaccgtgaagaacgccacgttcacgtgggccaggaatgacccccccacg
ctgcatggcatcaccttctctgttccggaaggttccctggtggccgtggtgggccaggtg
ggctgtgggaaatcgtctctactctcagcactcttggccgagatggacaaggtggaggga
cacgtgactgtcaagggctcagtggcctacgtcccacagcaggcctggattcagaacatt
tctctccgagaaaacatcctttttggacgccagctacaggaacggtattataaggctgtg
gtagaagcctgtgccctcctcccagacctggaaatcctgcccagtggggaccggacagag
attggtgagaagggtgtgaacctgtccgggggccagaagcagcgcgtgagcctggcccgg
gccgtatactgcgactcagacgtctacctcctcgacgatcccctctcagccgtggacgcc
cacgtgggcaagcacatctttgaaaacgtgattggccccaaggggcttctgaagaacaag
acacggctcctggtcacgcacgccatcagctacctgccccagatggatgtcatcatagtc
atgagtggcggcaagatctccgagatgggctcctaccaggagctattggctcgggacggc
gccttcgccgagttcctgcgtacctatgccagcgcggagcaggagcaggggcagccggag
gacggattagcaggtgtcggcggtccagggaaggaggtgaaacagatggagaacggcatg
ctggtgacagacactgcagggaagcaaatgcagaggcagctcagcagctcctcctcctac
agcggagatgtgagccggcnnnnnnnnnnnnnnnnnnnnctgcggaagcccgggcccacg
gaggagacctggaagctcgtggaggcagacaaggctcagacggggcaggtcaagctgtcc
gtgtactgggactacatgaaggcaattggacttttcatctcctttctgagcatcttcctt
ttcctgtgtaaccacgtggcttccctggtctctaactattggctcagtctctggacggat
gaccccattgtcaacgggacccaggagcacacgcaagtccggctgagtgtctatggagcc
ctgggcatttcacaaggtatcacggtgttcggctactccatggccgtgtccatcgggggc
atcttcgcctcccgccgcctgcacctggacctactgcataacgtcctccggtcgcccata
agcttcttcgagcggacccccagcgggaacctggtgaaccgcttctccaaggagctggac
acggtggactcgatgatcccgcaggtcatcaagatgttcatgggctccctgttcaatgtc
atcggcgcctgcatcatcatcctgctggccacgcccatggctgccgtcatcatcccgccc
ctgggcctcatctacttcttcgtgcagaggttctacgtggcctcctcccggcagctgaag
cgcctggagtcggtcagccgctcgccggtttattcccacttcaacgagaccttgctgggc
gtcagcgttatccgcgccttcgaggagcaggaacgcttcatccgccagagcgacctgaag
gtggacgagaaccagaaggcctactaccccagcatcgtggccaacaggtggctggccgtg
cggctggagtgtgtgggcaactgcatcgtcctgttcgcctcgctgtttgccgtgatttcc
cggcacagcctcagtgcaggcttggtgggcctctcggtgtcttactccctgcaggtcacc
acatatttgaactggctcgttcggatgtcgtccgagatggagaccaacattgtggccgtg
gagagactcaaggaatattcggaaactgagaaggaggctccctggcaaatccaggatatg
gcaccgcccaaggactggccccaggtgggccgagtggagttccgggactacggcctgcgg
taccgagaggacctggacttggttctgaagcacatcaacgtcaccatcgacggtggggag
aaggttggcatcgtggggcggacaggagccgggaagtcatccctgaccctgggcttgttt
cggatcaaagagtcagccgagggagagataatcattgatgacatcaacatcgccaagatc
ggcctgcatgacctccgcttcaagatcaccatcatcccccaggacccygttttgttttcg
ggttccctccgcatgaacctggacccgttcagccagtactcggatgaagaggtctggacg
tccctggagctcgcccacctgaagggcttcgtgtcggcccttcccgacaaactgaaccac
gagtgtgcggaaggcggggagaacctcagcgtcgggcaacgccagcttgtgtgcctggcc
cgggccctgctgaggaagacgaagatcctcgtgttggacgaagccacggcggccgtggac
ctggaaacggacgacctcattcagtccaccatccggacgcaatttgatgactgtaccgtc
ctcaccatcgctcaccggctcaacaccatcatggactacacgagggtgatcgtcctggac
aaaggggagatccaggagtggggctccccctctgacctcctgcagcagagaggtctcttc
tacagcatggccaaagattctggcttggtgtga |
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