KEGG   Priestia megaterium DSM 319: BMD_1273
Entry
BMD_1273          CDS       T01219                                 
Symbol
metH
Name
(GenBank) methionine synthase, vitamin-B12 dependent
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
bmd  Priestia megaterium DSM 319
Pathway
bmd00270  Cysteine and methionine metabolism
bmd00450  Selenocompound metabolism
bmd00670  One carbon pool by folate
bmd01100  Metabolic pathways
bmd01110  Biosynthesis of secondary metabolites
bmd01230  Biosynthesis of amino acids
bmd04980  Cobalamin transport and metabolism
Module
bmd_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:bmd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    BMD_1273 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    BMD_1273 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    BMD_1273 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    BMD_1273 (metH)
Enzymes [BR:bmd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     BMD_1273 (metH)
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding_2 B12-binding CdhD His_biosynth
Other DBs
NCBI-ProteinID: ADF38134
UniProt: D5DBM3
Position
complement(1261021..1264464)
AA seq 1147 aa
MSSLIEQQLKKRILVIDGAMGTMIQDADLTAEDFGGEEYEGCNEYLTRTAPHVIQRIHEE
YFAAGADIIETNTFGSTSTVLDEYDLGHLAYELNIEAVKLACAARDKYSTPEWPRFVAGA
IGPTTKTLSVTGGITFPELVESYEEQARGLLDGGVDLLLVETCQDMLNVKAAFLGITAAF
EKLKIEVPIMISGTIEPMGTTLAGQDIESFYLSLEHMKPLSVGLNCATGPEFMTDHIRSL
SDLATSAVSCYPNAGLPDEEGNYHESPELLAQKIKGFADKGWLNFVGGCCGTTPAHIKAL
AEAVKEVAPRSLDRSEHNHAVTGIEPLVYDDSMRPLFVGERTNVIGSRKFKRLIAEGKIE
EASEIARAQVKNGAHVIDICLADPDREEMEDMEEFIQEVVKKVKVPLVIDSTDEKVIEKA
LTYSQGKVIINSINLEDGEERFDAILPLVKKFGAALVVGTIDETGMAVTAERKVEIAKRS
HDLLVEKHGFNPKDIIFDPLVFPVGTGDEQYIGSAEETVKGIKMIKEALPDCLTILGVSN
VSFGLPPVGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASIPEAEIELANALLFNTTDE
TLSTFTDFYRDKKKEAKVEISTLTLEERLAMYIVEGTKEGLLPDLEQALAQYDDPLDIIN
GPLMKGMAEVGRLFNDNQLIVAEVLQSAEVMKASVAFLEPHMEATENDSGKGKVILATVK
GDVHDIGKNLVDIILSNNGFKVIDLGIKVTPQQLIEAVKEEKPDIIGLSGLLVKSAQQMV
LTAQDLTQSSIDVPIMVGGAALSRKFTDFKIAPEYEGAVLYAKDAMDGLALANKLQNKEE
VIQLLADLKTRQEKKVTVRERQPQTAQAATAVLERSAISTDAPVFVPADLKRHVVKHYDL
AQVLPYINWQMLLGHHLGLKGKVNKLLAEKDERAVQLKETVDDLLELALKENLIKPAVIY
QFFPAQADGNDLIIYDPADEKTEIERFTFPRQTKGQFLCLSDFAKPKEKEMDYVCFFSVT
AGTGIRERAAKFKENGEFLKSHVFQALALELAEGLAERVHQQIRDRWGFPDSPDFTMAER
FSAKYQGQRFSFGYPACPDLEDQAKLFKLLKPEDIGIQLTDGFMMEPEASVTALVFAHPE
AKYFNVL
NT seq 3444 nt   +upstreamnt  +downstreamnt
atgagctcacttatcgaacaacaactaaagaagcgaatactcgtcatcgatggagcaatg
ggaacgatgattcaagatgctgatttaaccgctgaagattttggcggcgaagaatatgaa
ggctgcaacgaatatttgactcgaacagcgcctcatgtgattcagcgcattcatgaagag
tactttgcagcaggtgctgacatcattgaaaccaatacgtttggctcaacatctaccgta
cttgatgaatacgatttaggtcacttggcgtatgaattgaatatcgaagctgtgaagctt
gcttgtgcagcccgcgataaatattcaactcccgaatggcctaggttcgtagctggagct
atcggtcctaccactaaaactctctctgttaccggaggtattacattccctgagttagta
gaatcgtacgaagagcaagctcgaggtttgttagacggcggcgttgacttgcttttagtc
gaaacctgtcaagacatgctgaacgtaaaagccgcatttttaggcattacagcggcgttt
gaaaaactaaaaatcgaagttcctattatgatttcaggaacaattgagccgatgggaaca
actctcgctggtcaagatatcgaatctttttacttatcactggaacatatgaagcctctt
tcagtcggacttaactgcgcgacaggccctgaatttatgacggatcatattcgctctctt
tcagacctagccacttcagcagttagttgttatccaaacgctggacttccggatgaagaa
ggcaattatcatgaatcccctgagctgcttgctcaaaaaattaaagggtttgctgataaa
ggctggctgaactttgtaggcggatgctgcggtacaacgcctgctcatattaaagcactg
gctgaagcggtaaaagaggttgcgccccgttcgcttgatcgctccgagcataaccatgct
gtaaccggtattgaaccacttgtatatgacgattctatgcgccctctttttgtgggagaa
cgtacgaatgtaatcggttctcgcaagttcaagcgtctgattgcggaagggaaaattgaa
gaagcatctgaaattgcgcgtgctcaagttaaaaatggtgctcacgttattgatatttgc
ttagcggatccggaccgtgaggaaatggaagacatggaggaatttattcaagaagttgta
aaaaaagtgaaggttcctcttgtaatcgattcaaccgacgagaaagttattgaaaaagct
ttaacgtactcacaaggtaaggtcattattaactccattaacttagaagatggtgaagag
cgttttgatgcaatcttaccgctagtaaaaaaattcggtgcagctctggttgtcggtaca
atcgatgaaacaggcatggccgttactgcagaacgaaaagtagagattgctaaacgctca
catgatctgcttgttgaaaaacatggctttaatccaaaagatattatttttgaccctctt
gtgtttcctgtagggactggtgatgaacaatatattggttctgctgaagaaacagttaag
ggaattaaaatgattaaagaagccctgcctgattgcctgaccattcttggcgtaagtaac
gtgtcattcggtcttcctccagtcggacgtgaagtactaaatgcggtttacctttatcac
tgtacgcaggctggactcgattatgccattgttaataccgaaaagttagagcgctatgct
tctattccagaagctgaaattgagcttgctaatgcgttattatttaacacaactgatgaa
acgttaagcacgtttaccgacttttatcgtgataaaaagaaagaagcaaaagtagaaatt
tctacgttaacactcgaagaacgattggcaatgtatattgtcgaaggtacaaaagaaggg
ttgcttcctgatttagaacaggctttagctcaatatgatgatccgttagatattattaac
ggaccgcttatgaaggggatggcggaagttggacgtttgtttaatgacaaccagctgatt
gtagcagaagtgcttcaaagtgcggaagttatgaaagcatccgttgcctttttagaacct
cacatggaagcaactgaaaatgattctggaaaaggcaaagttattcttgcaacggttaaa
ggcgacgtgcacgatatcggtaaaaacttagtagacatcattttaagcaacaatggtttt
aaagtaattgatttaggaattaaagtaacgccccagcagctgattgaagcagtaaaagaa
gaaaagccagacatcattggcctgtcaggtcttctagtaaagtcagctcagcaaatggtt
ttgactgcccaggatttaacacaatcaagcattgatgttccaattatggtaggaggcgct
gccctttcccgtaaatttactgactttaaaattgccccggaatatgaaggtgcggtcctc
tacgccaaagatgcgatggacggattagcgttagcaaataagctgcagaacaaagaagaa
gttattcagcttttagcagatttaaaaacgcggcaagaaaagaaagtaacggttcgagaa
cgccagcctcaaaccgctcaagcagctaccgctgttttagaaagatccgccatttcaacg
gacgctcctgtttttgtaccggctgatttaaagcggcacgttgtcaaacactacgatttg
gcacaggttcttccgtatattaactggcagatgcttttaggccatcacttaggactaaaa
ggaaaagtgaataaactgcttgctgaaaaagacgagcgcgctgttcaattaaaagaaacc
gttgatgacctgctcgagctggcactaaaagaaaacttaattaagccagcagttatttat
cagttcttccctgctcaagcagacggaaatgatttaattatttatgatcctgctgatgaa
aaaacagaaattgaacgctttaccttccctcggcaaacaaaaggacagttcctgtgctta
tctgattttgcaaagcctaaagaaaaagagatggactatgtatgtttcttctctgtaaca
gcaggaacaggcattcgcgaacgcgcggcgaaattcaaagaaaacggcgagtttttaaag
agtcacgtgttccaagctcttgcgcttgaactagctgaaggattagcagaacgtgttcat
cagcaaattcgtgaccgctggggattccctgattcgcctgactttacaatggcggagcgt
ttttcagccaaataccaaggtcagcgtttttcattcggatatcctgcatgtccagacctt
gaagaccaagcaaaactgtttaaattacttaaacctgaagacatcggcattcagttaaca
gacggtttcatgatggaaccagaagcttctgttacagcccttgtttttgcacatcctgaa
gcgaaatattttaacgtattgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (7)   
   Pfam (7)   
All databases (33)   

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