KEGG   Brucella melitensis bv. 1 16M: BMEI0589
Entry
BMEI0589          CDS       T00072                                 
Name
(GenBank) nad-dependent DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
bme  Brucella melitensis bv. 1 16M
Pathway
bme03030  DNA replication
bme03410  Base excision repair
bme03420  Nucleotide excision repair
bme03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:bme00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    BMEI0589
   03410 Base excision repair
    BMEI0589
   03420 Nucleotide excision repair
    BMEI0589
   03430 Mismatch repair
    BMEI0589
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:bme03032]
    BMEI0589
   03400 DNA repair and recombination proteins [BR:bme03400]
    BMEI0589
Enzymes [BR:bme01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     BMEI0589
DNA replication proteins [BR:bme03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     BMEI0589
DNA repair and recombination proteins [BR:bme03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     BMEI0589
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     BMEI0589
   MMR (mismatch excision repair)
    DNA ligase
     BMEI0589
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      BMEI0589
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT HHH
Other DBs
NCBI-ProteinID: AAL51770
UniProt: Q8YI56
Position
I:612275..614434
AA seq 719 aa
MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFP
ALVRDDSPSRRVGAAPALAIFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDS
IAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVV
EVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWG
EMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVY
KVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVG
GVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKR
GEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQ
VEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIAL
HRFLFGLGIRHVGEVNAKRLARAYLSYAAFKKAALEAVPPKEGDRTDKGSEAWQDMLAVE
GIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMS
RDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
NT seq 2160 nt   +upstreamnt  +downstreamnt
atgtccgatatttccgtcgagaaactgaccgaactcgaagctgccgccgaactggaacgg
ctggcgcgcgcgattgctcatcacgacgagctttatcacgccaaggacaggccggaaatt
tccgatgcggcttatgatgcactgaagcggcgcaacgaggcgattgaagcgcactttccg
gcacttgtccgcgatgacagcccgtcgcggcgtgtgggtgcagccccggcgcttgccatc
tttgcgcctgttgttcacgcgcggcccatgctgtcgctggataatgcctttagtgatgag
gacgtgcgtgattttgttggcagcgtctatcgctttctgggccaactgccggatgattcc
atcgcctttaccgcagaaccgaagatcgatgggctttccatgtcgatccgttacgagaat
ggaattctggttagcggtgcgacacgcggggatggcacaacgggcgagaatgtaacagcc
aatatccgcaccattgctgaaatcccgaacaggcttccggcaggtgcgcctgctgtcgtg
gaagtgcgcggcgaggtctatatggccaagagcgactttctgacgctcaatgcgcagatg
gaggcggagggcaagcagacctatgtgaacccgcgcaatacggcagcaggttcgctgcgc
cagcttgatgcgaaggtgacggcaagccgcaagctcaggttcttcgcctatgcctggggg
gaaatgtcggacatgcctgcggatacgcaattgggcatggtcgaggtttttcgccaatgg
ggctttccggtcaatccgttgatgaagcggttcaacagcgtggatgggttgcttgcgcat
tatcgcgccatcggcatggagcgtcccacgctggattacgatatcgacggtgttgtttac
aaggtggaccggctcgacctgcaaacccggcttggttttcgctcgcgcagcccgcgctgg
gcgattgcgcataaattcccggcggaacaggcgctcaccattttgcgcggcatcgatatt
caggtgggccgcactggcgcgctgacgccggtggcgcggctggagccaatcaccgtcggc
ggtgtggttgtgaccaacgcgacgctgcacaatgaggactatatcaagggcataggtcag
aagggcgagccgatccgggaggggcgcgatatccgcattggcgatagcgtgatcgtgcag
cgcgcgggcgatgtcatcccgcagatcgtggatgtggtgcttgaggaaggcaaaaaacgc
ggcgagccttatcagtttccccatgtctgccccgcctgcggcagccatgccgtgcgcgag
gagggcgaggcggtacgccgctgcaccggcgggctgatctgccctgcgcaggcggtggaa
cgcatccgccattttgtgtcgcgcaatgccttcgacattgaggggcttggcgaaaagcag
gtcgagttcttcttcaatgcggaagatccggccctttgcatccgctcgcctgccgatatt
ttcacactgaaaaagcggcaggaaaactcgctgaccaagcttcagaatatcgaaggcttt
ggcgcaacttccgtgaagaagctttatgacgccatcgatgcgcggcgcgagattgcactc
caccgctttctgtttggtcttggcatccgccatgtgggcgaggtgaatgccaagcgcctt
gcccgcgcctatctttcatatgccgcttttaagaaggcggcgctggaggctgtgccgcca
aaagaaggcgaccgcaccgacaagggcagcgaagcgtggcaggacatgctggccgtggag
gggatcggttccatcgtggcggaagccgtggtcgatttttatggcgagccgcataaccgc
gaagtgctggccgcacttcttgccgaagtaacgccgcttgatgaggaagcgcgtgtggcg
accggttcgcccgtcgagggcaagacggtggttttcaccggcagtctggagcgcatgtca
cgcgatgaagcgaaggctatggctgagcgccatggcgcgaagacggcaggctctgtctcc
aagaagaccgatctcgtggtggcagggccgggggccggttccaagcttgccaaggcgacg
gaactgggcattgaggttatcaatgaagacgactggttcaagcttgttggggaggattga

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