KEGG   Brucella melitensis ATCC 23457: BMEA_A0186
Entry
BMEA_A0186        CDS       T00867                                 
Symbol
cobA
Name
(GenBank) uroporphyrin-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
bmi  Brucella melitensis ATCC 23457
Pathway
bmi00860  Porphyrin metabolism
bmi01100  Metabolic pathways
bmi01110  Biosynthesis of secondary metabolites
bmi01120  Microbial metabolism in diverse environments
bmi01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:bmi00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    BMEA_A0186 (cobA)
Enzymes [BR:bmi01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     BMEA_A0186 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     BMEA_A0186 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     BMEA_A0186 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M
Other DBs
NCBI-ProteinID: ACN99989
UniProt: C0RGN2
Position
I:190162..191568
AA seq 468 aa
MSLSQTRLLADFPAFFRVSGEVVAVVGGGEEALNKARLVAQTAARLRIIAEKAEPHLAAF
IESHGVEHIASPFAPELLDGAKLVFVATGDEAGDRAAAAAARARKIPVNVVDRPALCDFL
TPAIVNRAPVTIAIGSQGTAPVLAQMVRARIDAAFSPRLGELAHFAESWRPLVERALPKG
LARRGFWRTFFSGKVARAVESGDHEAAHRAAAELIGQGQDASGHVWLVGAGPGAEDLLTL
RAQRVLMEADVIVHDALVPEGVIAMGRRDAERLPVGKRKGCHSKSQGEINRLLVKLGQEG
KRVVRLKSGDPLVFGRAGEEMAALRAAGIGFEVVPGITSAFAAAADMELPLTLRGVASSL
VFTTGHDMTGDVLPGWAKLAVYMGSTVAASVASRLIAAGLHEDTAVAVVENASRSNKRMF
HGTLKDLPQLENRKELSGPVMVVIGDAVAGAAIGRAQALSLKPVPVAA
NT seq 1407 nt   +upstreamnt  +downstreamnt
gtgtctttatcgcaaacgcgacttctggctgattttcctgctttcttccgggtttcgggc
gaagtggtggcggtcgtgggtggtggcgaggaagccttgaacaaggctcgcctcgtggcg
cagacggctgcgcgcctgcgcatcattgctgaaaaggctgagccgcatcttgccgctttt
attgaaagccatggggtggagcatattgcgtcaccctttgcgccggaactgctggatggt
gcgaagctcgtttttgtcgcgaccggcgatgaggccggggatcgtgccgccgctgccgcc
gcaagggcccgcaaaattccggtcaatgtggtggaccgtcccgccctttgcgattttctg
acacctgccatcgtcaatcgtgcgccggtcacgatcgccatcggttcgcagggaaccgcc
ccggttttggcgcagatggtgcgtgcgcgtatcgatgcagccttttcgccgcgtcttggc
gagcttgcgcattttgcggaaagctggcgccctctggtcgagcgggcgcttccaaaaggg
cttgcgcggcgtggtttctggcgcacattcttttcgggaaaagtggcccgcgcggtggag
agtggcgaccacgaggcggcgcacagggctgcggcggaactgatcgggcaggggcaggac
gcttccggccatgtctggctggttggggccggtcccggtgctgaagaccttttgacgctg
cgcgcccagcgcgtgctgatggaagccgatgtgatcgttcatgatgcgctggtgccggaa
ggcgtcatcgccatgggacgccgcgacgccgagcgcctgccggtaggcaagcgcaagggt
tgccattccaaaagccagggtgagatcaaccgcctgctggtgaagctggggcaggagggc
aagcgcgtggtgcgcctgaaatccggcgatccgctggtctttggccgtgcgggtgaggaa
atggccgccttgcgcgccgccggaataggctttgaggtggtgccgggcatcacctctgcc
tttgccgctgccgccgatatggaactgccgctgaccttgcgcggcgtcgcgtcctcgctc
gtcttcaccacgggccatgacatgaccggcgatgtgctgcccggctgggcgaagcttgcc
gtctatatgggctccacggttgccgcttccgttgcctcgcgtctgattgccgccggcctg
catgaggatacggcggttgcagtggtggaaaatgcaagccgcagcaacaagcgcatgttc
catggcacgctgaaggatttgccgcagcttgaaaaccgcaaggagctttccggcccggtc
atggtggtcattggcgatgccgtcgccggtgccgccatcggcagggcgcaggccctttcc
ctgaaacctgttcccgtcgcagcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (34)   

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