KEGG   Brucella melitensis ATCC 23457: BMEA_A1468
Entry
BMEA_A1468        CDS       T00867                                 
Symbol
ligA
Name
(GenBank) DNA ligase, NAD-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
bmi  Brucella melitensis ATCC 23457
Pathway
bmi03030  DNA replication
bmi03410  Base excision repair
bmi03420  Nucleotide excision repair
bmi03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:bmi00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    BMEA_A1468 (ligA)
   03410 Base excision repair
    BMEA_A1468 (ligA)
   03420 Nucleotide excision repair
    BMEA_A1468 (ligA)
   03430 Mismatch repair
    BMEA_A1468 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:bmi03032]
    BMEA_A1468 (ligA)
   03400 DNA repair and recombination proteins [BR:bmi03400]
    BMEA_A1468 (ligA)
Enzymes [BR:bmi01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     BMEA_A1468 (ligA)
DNA replication proteins [BR:bmi03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     BMEA_A1468 (ligA)
DNA repair and recombination proteins [BR:bmi03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     BMEA_A1468 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     BMEA_A1468 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     BMEA_A1468 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      BMEA_A1468 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT HHH
Other DBs
NCBI-ProteinID: ACO01181
UniProt: C0RE59
Position
I:complement(1393992..1396151)
AA seq 719 aa
MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFP
ALVRDDSPSRRVGAAPALATFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDS
IAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVV
EVRGEVYMAKSDFLTLNAQMAAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWG
EMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVY
KVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVG
GVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKR
GEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQ
VEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIAL
HRFLFGLGIRHVGEVNAKRLARAYLSYAAFEKAALEAVPPKEGDRTDKGSEAWQDMLAVE
GIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMS
RDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
NT seq 2160 nt   +upstreamnt  +downstreamnt
atgtccgatatttccgtcgagaaactgaccgaactcgaagctgccgccgaactggaacgg
ctggcgcgcgcgattgctcatcacgacgagctttatcacgccaaggacaggccggaaatt
tccgatgcggcttatgatgcactgaagcggcgcaacgaggcgattgaagcgcactttccg
gcacttgtccgcgatgacagcccgtcgcggcgtgtgggtgcagccccggcgcttgccacc
tttgcgcctgttgttcacgcgcggcccatgctgtcgctggataatgcctttagtgatgag
gacgtgcgtgattttgttggcagcgtctatcgctttctgggccaactgccggatgattcc
atcgcctttaccgcagaaccgaagatcgatgggctttccatgtcgatccgttacgagaat
ggaattctggttagcggtgcgacacgcggggatggcacaacgggcgagaatgtaacagcc
aatatccgcaccattgctgaaatcccgaacaggcttccggcaggtgcgcctgctgtcgtg
gaagtgcgcggcgaggtctatatggccaagagcgactttctgacgctcaatgcgcagatg
gcggcggagggcaagcagacctatgtgaacccgcgcaatacggcagcaggttcgctgcgc
cagcttgatgcgaaggtgacggcaagccgcaagctcaggttcttcgcctatgcctggggg
gaaatgtcggacatgcctgcggatacgcaattgggcatggtcgaggtttttcgccaatgg
ggctttccggtcaatccgttgatgaagcggttcaacagcgtggatgggttgcttgcgcat
tatcgcgccatcggcatggagcgtcccacgctggattacgatatcgacggtgttgtttac
aaggtggaccggctcgacctgcaaacccggcttggttttcgctcgcgcagcccgcgctgg
gcgattgcgcataaattcccggcggaacaggcgctcaccattttgcgcggcatcgatatt
caggtgggccgcactggcgcgctgacgccggtggcgcggctggagccaatcaccgtcggc
ggtgtggttgtgaccaacgcgacgctgcacaatgaggactatatcaagggcataggtcag
aagggcgagccgatccgggaggggcgcgatatccgcattggcgatagcgtgatcgtgcag
cgcgcgggcgatgtcatcccgcagatcgtggatgtggtgcttgaggaaggcaaaaaacgc
ggcgagccttatcagtttccccatgtctgccccgcctgcggcagccatgccgtgcgcgag
gagggcgaggcggtacgccgctgcaccggcgggctgatctgccctgcgcaggcggtggaa
cgcatccgccattttgtgtcgcgcaatgccttcgacattgaggggcttggcgaaaagcag
gtcgagttcttcttcaatgcggaagatccggccctttgcatccgctcgcctgccgatatt
ttcacactgaaaaagcggcaggaaaactcgctgaccaagcttcagaatatcgaaggcttt
ggcgcaacttccgtgaagaagctttatgacgccatcgatgcgcggcgcgagattgcactc
caccgctttctgtttggtcttggcatccgccatgtgggcgaggtgaatgccaagcgcctt
gcccgcgcctatctttcatatgccgcttttgagaaggcggcgctggaggctgtgccgcca
aaagaaggcgaccgcaccgacaagggcagcgaagcgtggcaggacatgctggccgtggag
gggatcggttccatcgtggcggaagccgtggtcgatttttatggcgagccgcataaccgc
gaagtgctggccgcacttcttgccgaagtaacgccgcttgatgaggaagcgcgtgtggcg
accggttcgcccgtcgagggcaagacggtggttttcaccggcagtctggagcgcatgtca
cgcgatgaagcgaaggctatggctgagcgccatggcgcgaagacggcaggctctgtctcc
aagaagaccgatctcgtggtggcagggccgggggccggttccaagcttgccaaggcgacg
gaactgggcattgaggttatcaatgaagacgactggttcaagcttgttggggaggattga

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