KEGG   Bos mutus (wild yak): 102267343
Entry
102267343         CDS       T02919                                 
Symbol
TSC2
Name
(RefSeq) tuberous sclerosis 2
  KO
K07207  tuberous sclerosis 2
Organism
bom  Bos mutus (wild yak)
Pathway
bom04072  Phospholipase D signaling pathway
bom04115  p53 signaling pathway
bom04140  Autophagy - animal
bom04150  mTOR signaling pathway
bom04151  PI3K-Akt signaling pathway
bom04152  AMPK signaling pathway
bom04211  Longevity regulating pathway
bom04218  Cellular senescence
bom04714  Thermogenesis
bom04910  Insulin signaling pathway
bom04919  Thyroid hormone signaling pathway
bom05163  Human cytomegalovirus infection
bom05165  Human papillomavirus infection
bom05168  Herpes simplex virus 1 infection
bom05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bom00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    102267343 (TSC2)
   04151 PI3K-Akt signaling pathway
    102267343 (TSC2)
   04152 AMPK signaling pathway
    102267343 (TSC2)
   04150 mTOR signaling pathway
    102267343 (TSC2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102267343 (TSC2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    102267343 (TSC2)
   04218 Cellular senescence
    102267343 (TSC2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102267343 (TSC2)
   04919 Thyroid hormone signaling pathway
    102267343 (TSC2)
  09149 Aging
   04211 Longevity regulating pathway
    102267343 (TSC2)
  09159 Environmental adaptation
   04714 Thermogenesis
    102267343 (TSC2)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    102267343 (TSC2)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    102267343 (TSC2)
   05163 Human cytomegalovirus infection
    102267343 (TSC2)
   05165 Human papillomavirus infection
    102267343 (TSC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bom01009]
    102267343 (TSC2)
Protein phosphatases and associated proteins [BR:bom01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102267343 (TSC2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP
Other DBs
NCBI-GeneID: 102267343
NCBI-ProteinID: XP_005886844
Position
Un
AA seq 1811 aa
MAKPASKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV
IGQICEVARTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR
ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
VNLVKFNSCYLDEYIASMVHMVCLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI
VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYHMCRIMEDRAYMEDAPLLRGAVFFVG
MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI
LXNIIERLLQQLQSLDSPELSAIVHDLLSTVEELCDQNEFHGSQERYFELVERCADQRPE
SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY
EEELINSVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARSLS
PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH
SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDCLETERSSEKKAG
GPLSPPAGXPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYKVLIF
TSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTR
QREMVYCLEQGLIYRCASQCVVALAVCSVEMPDVILKALPVLVVKLTHISATASMAIPLL
EFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPF
RKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVK
ELKESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTE
TCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLD
SGELQGGPELSSDPSMHVRQTKEAPAKLESQAGQQVYHGARDRVRSMSGGHGLRVGALDA
PACYFPSSPTSPGSQTAPASQPEKASAGSPLPAQKEKTNLAAYVPLLTQGWAEILVRRPT
GNTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKP
SPPPRSNTVASFSSLCQSRCQGKLHRSISWADSAVVLEEGGPGEAGLSAEPPELEDFEAT
LGSDGRCGRSDAFSRSSSTSSQEEKSFHAEELPPGGIPIERAVSSEGSRASVDLAFQPSQ
PLSKSSSSPELQTLQDILGDPGDKAEVGRLSPEAKARSQSGILDGEGAAWSAPGEERRGR
GPAQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKNRAGTSNTEKVPGIN
PSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSE
LAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAV
FHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDY
ECNLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPS
KWIARLRHIKRLRQRIREEAHYSSASLPLMQTHPPGHAKAPAQAPAESTPTYETGQRKRL
VSSVDDFTEFV
NT seq 5436 nt   +upstreamnt  +downstreamnt
atggctaagccagcaagcaaagattcaggcttgaaggagaagttcaagattcttttggga
ctggggactccacggccaaatcccaggtctgcagagggcaaacagactgagtttatcatc
accgcggaaatcctgagagagctgagtgttgaatgtggcctcaataatcgcatccgggtg
atagggcagatctgtgaggttgccagaacgaagaaattcgaagagcatgcggtggaagca
ctctggaaggccgtctcggacctgctgcagccagagcggccacccgaggcccggcatgcg
gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcctgggcgttctcagg
gccctcttcttcaaggtcatcaaggattacccctctaatgaagacctccacgagagactg
gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaagaagagctg
gcggactttgtcctgcagtggatggacgttggcctgtcctccgaattcctcctggtgctc
gtgaacttagtcaaattcaacagctgttaccttgatgagtacatcgcatccatggtccac
atggtctgcctgctgtgtgtccagaccgtgtcctccgtggacatagaggtgtctctgcag
gtgctggatgctgtggtctgctacaactgtctgccagccgagagcctccccctattcatc
gtcactctctgccgcaccatcaacgtcaaggagctctgtgaaccttgctggaagctgatg
cgcaacctcctgggcacccacctgggccacagcgccatctaccacatgtgccgcatcatg
gaagacagagcctacatggaggacgcaccactgctgagaggagccgtgttctttgttggc
atggctctctggggtgcccaccggctctattctctcaagaactccccaacatctgtgttg
ccatcgttttatgaggccatgacctgtccgaatgaggtggtgtcctacgagattgtcctc
tccataaccagactcatcaagaagtacaggagggagctccaggccgtgacctgggacatc
ctnnngaacatcatcgagcgcctgctccagcagctccagagcctggacagcccagagctg
agcgccatcgtgcacgacctgctgagcacagtggaggagctgtgtgaccagaacgagttt
cacggctcccaggagagatactttgaactcgtggagaggtgtgcggaccagaggcctgag
tcatcccttttaaacttaataacctacagggctcagtccatccatccagcgaaggacggc
tggatccacaacctgcagctgctgatggagaggtttttcaggaacgagtcacgcagcgcc
gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat
gaggaggagcttatcaactcagtggtcatctcgcagctctcccacatccctgaggataga
gaccaccaggtccggaagctggccactcagctgctggtagatctggccgaaggctgccac
acccaccacttcaacagcctgctggacattgttgagaaggtgatcgcccgttccctctct
ccgccccccgagctggaggagagggatgtggccgcgtactcggcctccttggaggatgtg
aagactgcggtcctggggctcctggtcatccttcagaccaagctgtatgccctgcctgcc
agccatgccacacgcgtgtatgagacgctggtcagccacattcagctccactacaagcac
agctacaccctgcccattgccagcagcatccgtctgcaggccttcgacttcctgctgcag
ctgcgggccgactcactgcaccgcctgggcctgcccagcaaagacgggcttgtgaggttc
agcccctactgcgtctgtgactgcctggagacagagaggagctccgagaagaaggccggg
ggccccctgtccccgcccgccgggncccctgcgggccctgctgtgcgcctcgggtccctg
ccctactccctgctcttccgtgttctgctgcagtgtctgaagcaggagactgactggaag
gtgctgaagctggtgctcagcaaactgcccgagtcgctgcgctataaggtcctcatcttc
acctccccatgcagtgtcgaccagctgtccgccgccctctgctccatgctttcaggtccc
aagaccctggagcggctccgaggcactccagaaggcttctccagaaccgacctgcatctc
gctgtggttcccgtgctgacagccctgatctcttaccataactacttggacaaaactaga
cagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgtgccagccagtgt
gtggtggccctggccgtgtgcagcgtggagatgcccgacgtcatcctcaaggcactgccc
gtcctggttgtgaagctcacacacatctcggccacggccagcatggccatcccgctcctc
gagttcctgtccactctggccagactgcctcacctctacaggaacttcgcagcagagcag
tatgccagtgtgtttgccatctccctgccgtataccaacccctccaagttcaatcagtac
atcgtgtgcctggcccatcacgtcatagccatgtggttcatcaggtgccgcctgcccttc
cggaaggactttgttccttacatcaccaagggtctgcgctccaacgtcctcctgtctttc
gatgacacccccgagaaggacagcttccgagcgcggagcaccagtctcaacgagaggccc
aagagtttgaggatagccagaccccccaaacaaggcttgaataactctccacccgtgaaa
gaactcaaggagagctctgcagccgatgccttccggtgccgcagcatcagtgtgtctgaa
catgtggtccgcagcaggatccagacctctctcacgagcgccagcttggggtctgcagac
gagaactcgatggcccaggccgacgacaacttgaaaaacctccacctggagctcacagag
acgtgtctggacatgatggccagatatgtgttctccaacttcacggcggtccccaagagg
tcccccgtgggagagttcctcctggctggtggcaggaccaaaacctggctggttgggaac
aagcttgtcaccgtgacgacaagcgtgggtaccgggacccggtcactgctaggcctggac
tctggagagctgcagggtggcccggagttgagctctgaccccagcatgcatgtgagacag
acaaaggaagcacccgccaagctggagtcccaagctgggcagcaggtgtaccacggagcc
cgggaccgggtccgctccatgtccgggggccatggccttcgcgtgggtgccttggacgct
ccagcctgctacttccccagcagccccacgtccccgggctcccagaccgctccagccagc
cagcccgagaaggcctcagctggcagcccgctcccagcacagaaggagaagacaaacctg
gctgcttacgtgcccctgctgacccagggctgggcagagatcctggtccgcaggcccaca
gggaacaccagctggctgatgagcctggagaacccgctcagccccttctcctcggacatc
aacagcatgccgctgcaggagctgtccaatgccctcatggccgccgagcgcttcaaggag
cgccgcgacacagccctgtacaagtcgctgtcggtgccggcggccggctcagccaagcca
tccccgcccccacgctccaacacagtggcctctttctcctccctgtgccagtccaggtgc
caaggaaagctgcacaggagcatttcctgggcagattctgcggtggtcctggaggaggga
ggtccaggtgaggctggtttgtctgcagagcctcccgagttggaagattttgaggcgaca
ctgggctccgacgggcgctgtgggcgcagcgacgctttcagcaggtcatcttccacctcc
agccaggaggagaagtcattccatgccgaggagttgcctcctgggggcatccccatcgag
cgggcggtctcctcggagggctcccgggcctccgtggacctcgccttccagccctctcag
cccctgagcaagtccagctcgtcacctgaactgcagaccctgcaggacatcctgggggac
cccggggacaaggctgaggtcggccggctgagccccgaggccaaggcccggtcgcagtca
gggatcctggacggggaaggtgccgcctggtcagccccgggtgaggaacgccggggtcgg
ggccctgcccagccagagggccccttgccttccagctgtccccgctcccccagcgggctg
cggccccgaggctacaccatctcggattcggccccgtcacgcaggggcaagagggtggag
agggatgccttcaagaaccgagcagggacctccaacaccgagaaggtgccaggcatcaac
cccagcttcgtgttcctgcagctctaccactcaccgttctttggtgacgagtccaacaag
ccaatccttttgcctaacgagtctttcgaacgatcagtgcagctccttgatcagatcccg
tcgtacgacacgcacaagatcgcggtcctgtacgtgggagaaggccagagcaacagcgag
ctcgccatcctgtccaacgagcatggctcctacaggtacacagagttcctcacggggctg
ggcaagctcatcgagctcaaggactgccagccggacaaggtgtacctgggcggcctggac
gtgtgcggcgaggatggccagttcacctactgctggcacgacgacatcatgcaagctgtc
ttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaag
cgccacctgggcaacgacttcgtgtccatcgtctacaacgactctggcgaggacttcaag
ttgggcaccatcaagggccaattcaacttcgtccacgtgattatcacgcccctggactac
gagtgcaacctggtgtctctgcagtgcaggaaagacatggagggccttgtggataccagc
atggccaagatcgtgtctgaccgaaacctgcccttcgtggcccgccagatggccctgcac
gccaatatggcctcgcaggtgcatcatagccgctccaatcccaccgacatttatccctcc
aagtggattgccaggctccgccacatcaagcggctgcgccagcggatccgtgaggaagcc
cactactcaagcgccagcctgcccctgatgcagacacaccctcctggtcatgccaaggct
ccagcacaggccccggctgagtccacgcccacctatgagacgggccagcggaaacggctg
gtctcctctgtggacgacttcactgagttcgtgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (15)   
   KEGG PATHWAY (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (27)   

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