KEGG   Bos mutus (wild yak): 102272241
Entry
102272241         CDS       T02919                                 
Symbol
CACNA1S
Name
(RefSeq) calcium voltage-gated channel subunit alpha1 S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
bom  Bos mutus (wild yak)
Pathway
bom04010  MAPK signaling pathway
bom04020  Calcium signaling pathway
bom04022  cGMP-PKG signaling pathway
bom04024  cAMP signaling pathway
bom04260  Cardiac muscle contraction
bom04261  Adrenergic signaling in cardiomyocytes
bom04270  Vascular smooth muscle contraction
bom04723  Retrograde endocannabinoid signaling
bom04725  Cholinergic synapse
bom04726  Serotonergic synapse
bom04727  GABAergic synapse
bom04911  Insulin secretion
bom04912  GnRH signaling pathway
bom04921  Oxytocin signaling pathway
bom04924  Renin secretion
bom04925  Aldosterone synthesis and secretion
bom04927  Cortisol synthesis and secretion
bom04929  GnRH secretion
bom04934  Cushing syndrome
bom04935  Growth hormone synthesis, secretion and action
bom05010  Alzheimer disease
bom05020  Prion disease
bom05022  Pathways of neurodegeneration - multiple diseases
bom05207  Chemical carcinogenesis - receptor activation
bom05410  Hypertrophic cardiomyopathy
bom05412  Arrhythmogenic right ventricular cardiomyopathy
bom05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bom00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102272241 (CACNA1S)
   04020 Calcium signaling pathway
    102272241 (CACNA1S)
   04024 cAMP signaling pathway
    102272241 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    102272241 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102272241 (CACNA1S)
   04929 GnRH secretion
    102272241 (CACNA1S)
   04912 GnRH signaling pathway
    102272241 (CACNA1S)
   04921 Oxytocin signaling pathway
    102272241 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    102272241 (CACNA1S)
   04924 Renin secretion
    102272241 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    102272241 (CACNA1S)
   04927 Cortisol synthesis and secretion
    102272241 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    102272241 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    102272241 (CACNA1S)
   04270 Vascular smooth muscle contraction
    102272241 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    102272241 (CACNA1S)
   04725 Cholinergic synapse
    102272241 (CACNA1S)
   04726 Serotonergic synapse
    102272241 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    102272241 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    102272241 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102272241 (CACNA1S)
   05020 Prion disease
    102272241 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    102272241 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102272241 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    102272241 (CACNA1S)
   05414 Dilated cardiomyopathy
    102272241 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102272241 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:bom04040]
    102272241 (CACNA1S)
Ion channels [BR:bom04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   102272241 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 102272241
NCBI-ProteinID: XP_005909328
Position
Un
AA seq 1862 aa
MEPAPAQDEGLRRKQAKKPVPEVLPRPPRALFCLTLQNPVRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNRLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNLIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SGWRPLFHIALLVLFMVVIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCARSGS
GRPCTISGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWP
WIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYLSWI
TQGEVMDVDDLREGKLALDEGGSDTESLYEIAGLNKVIQFIRHWRQWNRVFRWKCHDVVK
SRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVANRVLLALFTVEMLMKMYGLGLRQ
YFMSIFNRFDCFVVCSGLLEILLVESGAMSPLGISVLRCIRLLRIFKITKYWTSLSNLVA
SLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDSFPQALISVFQV
LTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESL
TSAQKAKAEERRRRKMSKGLPDKSEEEKVTVAKKLEQKPKGEGIPTTAKLKIDEFESNVN
EVKDPYPSADFPGDDEEDEPEVPISPRPRPLAELQLKEKAVPIPEASAFFIFSPTNKIRV
LCHRIVNATWFTNFILLFILLSSAALAAEDPLRAESVRNQILGYFDIGFTSVFTVEIVLK
MTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSTISVVKILRVLRVLRPLRAINR
AKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDLSKMTEEECRG
YYYVYKDGDPTQIEVRPRQWVHNAFHFDNVLSAMMSLFTVSTFEGWPELLYKAIDSHEED
KGPVYNHRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQ
YALKARPLRCYIPKNPYQYRVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHIS
DILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSG
GLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYV
ALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILL
ACSYGQLCDPESDYAPGEEYTCGTDFAYYYFLSFYMLCAFLIINLFVAVIMDNFDYLTRD
WSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVG
MNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKVWKRTSMKLLDQVI
PPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEI
RRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFLERTNSLAPHMANQRPLQF
TEIEMEEMESPVFLEDFPQSPSTHPLARANTNNANANVASGNGNHGNSPAFPSVHYEGEL
AGETETPATRGGLFGQPRGALGPHGKSRVEWPQGQLPRRRTPRAQAPAASCQHAGADSQV
PEEQSPTPGSLPGEAPPGSRTEDGTPGGPAPAMALLIREALVRGGLDSLAADANFIMATG
QALAEACRMEPREVEVAAAELLQGREALEGVPGARGCPGLGSSLGSLDLREGSQETLIPR
RP
NT seq 5589 nt   +upstreamnt  +downstreamnt
atggagccggccccggcccaggacgagggcctgcggaggaagcaggccaagaagcccgtc
ccggaggtcctgcccaggccgccccgggccttgttctgcttgaccctccagaaccccgtg
cggaaagcctgcatcagcatcgtcgagtggaaacccttcgagaccatcatcttactcacc
atctttgccaactgcgtggccctggccgtgtacctgcccatgccggaggacgacaacaac
agactgaacctcggcctggagaagctggaatacttcttcctcatcgtcttctccatcgag
gccgccatgaagatcattgcctacggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaacgtgctggatttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caggtcaacctcatccagagcaacacggccccgatgagcagcaaaggcgcgggcctggac
gtcaaggcactgcgggccttccgcgtgctccgcccgctccggctggtgtccggggtgccc
agtgggtggcggccgctcttccacatcgccctgctggtgctcttcatggtcgtcatctac
gccatcatcggcctcgagctcttcaagggcaagatgcacaagacctgctacttcatcggc
acggacatcgtggccacggtggagaatgagaagccgtccccctgcgcccggtcgggctcc
ggccgcccctgcaccatcagcggcagcgagtgccgtggcgggtggcccggccccaaccac
ggcatcacccacttcgacaacttcggcttctccatgctcaccgtgtaccagtgcatcacc
atggagggctggaccgacgtcctctactgggtgaatgatgccatcgggaacgagtggccc
tggatctactttgtcaccctcatcctgctgggctccttcttcatcctcaacctggtgctg
ggcgtcctgagcggggaattcaccaaggagcgggagaaggccaagtccagggggaccttc
cagaagctgcgggagaagcagcagctggaggaggacctccggggctacctgagctggatc
acgcagggcgaggtcatggacgtggatgacttgagagaagggaagctggctctggatgaa
ggcggctccgacacggagagcctgtacgaaatcgcgggcttgaacaaagttatccagttc
atccgacactggaggcagtggaaccgcgtcttccgctggaagtgccatgatgtggtgaag
tccagggtcttctactggctggtcatcctgatcgtcgctctcaacacactgtcgatcgcc
tcagagcaccaccaccagcctctctggttgacccacctgcaagacgtggccaaccgggtg
ctgctggccctgttcaccgtggagatgctgatgaagatgtacgggctgggcctgcgccag
tacttcatgtccatcttcaaccgcttcgactgcttcgtggtgtgcagcggcctcctggag
atcctgctggtggagtcgggtgccatgtcgcccctgggcatctcggtgctgcgctgcatc
cgtctgctgcggatcttcaagatcaccaagtactggacgtcgctgagcaacctggtggcg
tcgctgctcaactccatccgctccatcgcctcgctgctgctgctgctcttcctgttcatc
gtcatcttcgccctgctgggcatgcagctcttcgggggcaggtacgacttcgaggacacc
gaggtgcggcgtagcaacttcgacagcttcccacaggccctcatcagcgtcttccaggtg
ctgacaggagaggactggaactccgtgatgtacaacgggatcatggcctacggcggccca
tcctaccccggggtgcttgtctgcatttacttcatcatcctgtttgtttgtggcaactac
atcctgctcaacgtcttcctggccatcgctgtggacaacctggcagaggccgagagcctg
acttctgcccagaaggccaaggctgaagagcggagacgcaggaagatgtccaagggtctc
ccggacaagtcagaggaggagaaggtgacggtggccaagaagctggagcagaaacccaag
ggggaaggcatccccaccaccgccaagctgaagatcgacgagtttgaatccaacgtcaac
gaggtgaaggacccctatccctcagccgacttcccaggggacgacgaggaagacgagccc
gaggtcccaataagcccccggccccgtccgctggctgagctgcagctgaaggagaaggcg
gtgcccattccagaagccagtgccttcttcatcttcagccccaccaacaagatccgcgtc
ctgtgccaccgcattgtcaatgccacctggttcactaacttcatcctgctcttcatcctg
ctcagcagtgccgccctggccgccgaggaccccctccgggctgagtccgtgaggaaccag
atcctcgggtattttgacatcgggttcacctctgtcttcactgtggagattgtcctcaag
atgaccacctacggggccttcctgcacaagggctccttctgccgcaactacttcaacatt
ctggacctggtggtggtggccgtgtccctcatctccatgggactcgagtccagcaccatc
tccgtggtgaagatcctgagggtcctgagggtgctccgaccgctccgggccatcaacaga
gccaaaggcctgaagcatgtggtacagtgtgtgttcgtggccatccgcaccatcgggaac
atcgtcctggtcaccaccctcctgcagttcatgttcgcctgcatcggcgtccagctcttc
aaggggaagttcttcagctgcaatgacttgtccaagatgacggaggaggagtgcaggggc
tactactatgtgtacaaagatggagaccccacacagatagaggtgcgtccccgccagtgg
gtgcacaacgccttccacttcgacaacgtgctttcggccatgatgtccctcttcaccgtg
tccaccttcgagggatggcctgagctgctgtacaaggccattgactctcatgaggaggac
aagggccccgtgtacaaccaccgcgtggagatggccattttcttcatcatctacatcatc
cttatcgccttcttcatgatgaacatcttcgtgggctttgtcatcgtcaccttccaggag
cagggggagactgagtacaagaactgtgagctggacaagaaccagcgccagtgcgtgcag
tacgccctgaaggcccggcccctgaggtgctacatccccaagaacccctaccagtaccgg
gtgtggtacatcgtcacctcctcctacttcgagtacctgatgttcgccctcatcatgctc
aacaccatctgcctgggcatgcagcactacaaccagtcggagcaaatgaaccacatctct
gacatcctcaacgtagccttcaccatcatcttcacactggagatggtcctcaagctcatg
gcgttcaaggccaggggctattttggggacccctggaacgtgtttgactttctgattgtc
atcggcagcatcatcgacgtcatcctcagtgagatcgacactttcctggcctccagcggg
ggactgtattgcctgggtggcggctgcgggaacgttgaccccgacgagagcgcccgcatc
tccagcgccttcttccgcctgttccgtgtcatgaggctgatcaagctgctgagccgcgcg
gagggcgtgcgcacgctgctctggactttcatcaagtccttccaggccctgccctacgtg
gctctgctcatcgtcatgctcttcttcatctacgcagtcatcggcatgcagatgttcggg
aagatcgccttggtggacgggacccagatcaaccggaacaacaacttccagaccttcccc
caggcggtgctgctgctcttcaggtgcgccacgggggaggcgtggcaggagatcctgctg
gcctgcagctacggccagctgtgtgaccccgagtcggactacgcccccggggaggagtac
acctgtggcacggacttcgcctactactacttcctcagcttctacatgctgtgcgccttc
ctgatcatcaacctctttgtggccgtcatcatggacaactttgactacctgacacgggac
tggtccatcctgggccctcatcacctggatgagttcaaggccatctgggcggagtacgac
ccggaggctacgggcaggatcaagcacctggacgtggtgacccttctgaggaggatccag
cccccgctgggcttcgggaagttctgcccccaccgggtagcgtgtaagcggctggtgggc
atgaacatgcccctcaacagcgacggcacggtcaccttcaatgccacgctcttcgccctg
gtgcgcacagctctgaagatcaagacggaaggtaacttcgagcaggccaacgaggagctg
cgagccatcatcaagaaggtctggaagaggaccagcatgaagctcctggaccaggtcatc
cctcccataggagatgacgaggtgacggtggggaagttctacgccacgttcctcatccag
gagcacttccggaagttcatgaggcgccaggaggagtattatgggtaccggcccaagaag
gacaccgtgcagatccaggctggactgaggaccatcgaggaagaggcagcccctgagatc
cgccgcaccatctcgggagacctgacggccgaagaggagctggagagagccatggtggag
gccgcgatggaggaagggatcttccggaggaccggcggcctgtttggccaggtggacagc
ttcctggaaaggaccaactcgttggccccgcacatggccaaccagagacccctccagttt
actgaaattgagatggaggagatggaatcgcccgtcttcctggaggacttccctcaaagt
ccgagtacccacccccttgctcgtgccaacaccaacaatgccaacgccaacgttgccagt
ggcaacggcaaccatggcaacagcccagcatttcccagtgtccactacgaaggggagctc
gcaggggagacagagacgcctgccaccagaggaggactcttcggccagccccggggggcc
ctggggccccatggcaagtcccgagtggagtggccgcagggacagcttccccggagaagg
acgcccagggcccaggcccccgctgcctcctgccagcacgcgggagcagactcccaggtg
cccgaggagcagagccccaccccagggtccctgcccggggaggcaccgcccggcagtagg
acagaggacggaacccctgggggtccagctccagccatggccctgctgatccgcgaggct
ctggttcgagggggcctggacagcttggcggcggatgctaacttcatcatggccacgggc
caggcgctggcggaggcctgccggatggaaccgcgggaagtggaggtggcagccgcagag
cttctgcagggacgcgaggccctggagggcgtgcctggtgcccgagggtgcccaggcctc
gggtcctccctgggcagcctcgacctgcgtgagggctcccaggagaccctgattccccgc
aggccatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (27)   
   KEGG PATHWAY (27)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (41)   

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