KEGG   Bos mutus (wild yak): 102274117
Entry
102274117         CDS       T02919                                 
Symbol
ADCY2
Name
(RefSeq) adenylate cyclase 2
  KO
K08042  adenylate cyclase 2 [EC:4.6.1.1]
Organism
bom  Bos mutus (wild yak)
Pathway
bom00230  Purine metabolism
bom01100  Metabolic pathways
bom01522  Endocrine resistance
bom04015  Rap1 signaling pathway
bom04020  Calcium signaling pathway
bom04022  cGMP-PKG signaling pathway
bom04024  cAMP signaling pathway
bom04062  Chemokine signaling pathway
bom04072  Phospholipase D signaling pathway
bom04114  Oocyte meiosis
bom04211  Longevity regulating pathway
bom04213  Longevity regulating pathway - multiple species
bom04261  Adrenergic signaling in cardiomyocytes
bom04270  Vascular smooth muscle contraction
bom04371  Apelin signaling pathway
bom04540  Gap junction
bom04611  Platelet activation
bom04713  Circadian entrainment
bom04714  Thermogenesis
bom04723  Retrograde endocannabinoid signaling
bom04724  Glutamatergic synapse
bom04725  Cholinergic synapse
bom04727  GABAergic synapse
bom04750  Inflammatory mediator regulation of TRP channels
bom04911  Insulin secretion
bom04912  GnRH signaling pathway
bom04913  Ovarian steroidogenesis
bom04914  Progesterone-mediated oocyte maturation
bom04915  Estrogen signaling pathway
bom04916  Melanogenesis
bom04918  Thyroid hormone synthesis
bom04921  Oxytocin signaling pathway
bom04922  Glucagon signaling pathway
bom04923  Regulation of lipolysis in adipocytes
bom04925  Aldosterone synthesis and secretion
bom04926  Relaxin signaling pathway
bom04927  Cortisol synthesis and secretion
bom04928  Parathyroid hormone synthesis, secretion and action
bom04934  Cushing syndrome
bom04935  Growth hormone synthesis, secretion and action
bom04970  Salivary secretion
bom04971  Gastric acid secretion
bom04972  Pancreatic secretion
bom04976  Bile secretion
bom05032  Morphine addiction
bom05163  Human cytomegalovirus infection
bom05166  Human T-cell leukemia virus 1 infection
bom05200  Pathways in cancer
bom05207  Chemical carcinogenesis - receptor activation
bom05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bom00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102274117 (ADCY2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102274117 (ADCY2)
   04371 Apelin signaling pathway
    102274117 (ADCY2)
   04020 Calcium signaling pathway
    102274117 (ADCY2)
   04072 Phospholipase D signaling pathway
    102274117 (ADCY2)
   04024 cAMP signaling pathway
    102274117 (ADCY2)
   04022 cGMP-PKG signaling pathway
    102274117 (ADCY2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102274117 (ADCY2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102274117 (ADCY2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102274117 (ADCY2)
   04062 Chemokine signaling pathway
    102274117 (ADCY2)
  09152 Endocrine system
   04911 Insulin secretion
    102274117 (ADCY2)
   04922 Glucagon signaling pathway
    102274117 (ADCY2)
   04923 Regulation of lipolysis in adipocytes
    102274117 (ADCY2)
   04912 GnRH signaling pathway
    102274117 (ADCY2)
   04913 Ovarian steroidogenesis
    102274117 (ADCY2)
   04915 Estrogen signaling pathway
    102274117 (ADCY2)
   04914 Progesterone-mediated oocyte maturation
    102274117 (ADCY2)
   04921 Oxytocin signaling pathway
    102274117 (ADCY2)
   04926 Relaxin signaling pathway
    102274117 (ADCY2)
   04935 Growth hormone synthesis, secretion and action
    102274117 (ADCY2)
   04918 Thyroid hormone synthesis
    102274117 (ADCY2)
   04928 Parathyroid hormone synthesis, secretion and action
    102274117 (ADCY2)
   04916 Melanogenesis
    102274117 (ADCY2)
   04925 Aldosterone synthesis and secretion
    102274117 (ADCY2)
   04927 Cortisol synthesis and secretion
    102274117 (ADCY2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102274117 (ADCY2)
   04270 Vascular smooth muscle contraction
    102274117 (ADCY2)
  09154 Digestive system
   04970 Salivary secretion
    102274117 (ADCY2)
   04971 Gastric acid secretion
    102274117 (ADCY2)
   04972 Pancreatic secretion
    102274117 (ADCY2)
   04976 Bile secretion
    102274117 (ADCY2)
  09156 Nervous system
   04724 Glutamatergic synapse
    102274117 (ADCY2)
   04727 GABAergic synapse
    102274117 (ADCY2)
   04725 Cholinergic synapse
    102274117 (ADCY2)
   04723 Retrograde endocannabinoid signaling
    102274117 (ADCY2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102274117 (ADCY2)
  09149 Aging
   04211 Longevity regulating pathway
    102274117 (ADCY2)
   04213 Longevity regulating pathway - multiple species
    102274117 (ADCY2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102274117 (ADCY2)
   04714 Thermogenesis
    102274117 (ADCY2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102274117 (ADCY2)
   05207 Chemical carcinogenesis - receptor activation
    102274117 (ADCY2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102274117 (ADCY2)
   05163 Human cytomegalovirus infection
    102274117 (ADCY2)
  09165 Substance dependence
   05032 Morphine addiction
    102274117 (ADCY2)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    102274117 (ADCY2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102274117 (ADCY2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102274117 (ADCY2)
Enzymes [BR:bom01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     102274117 (ADCY2)
SSDB
Motif
Pfam: Guanylate_cyc Adcy_cons_dom AC_N
Other DBs
NCBI-GeneID: 102274117
NCBI-ProteinID: XP_005905194
Position
Un
AA seq 913 aa
LPTWLQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYA
DIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNH
AKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLAN
HMEAGGVPGRVHISSVTLQHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQ
HLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHN
FQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKIIEKEYRA
TALPAFKYYVTCACLIFFCIFIVQVLVLPKTSILGISFGAAFLSLAFILFVCFAGQLLQC
SKKASASLLWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEETILPTANA
SNTSLSGASNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYN
TIFLHTHAPLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLW
KNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEGQVNAGSSEGRTSCHAVG
IQSVLAVVLCILVIITIPQRVTSADVSRCQGNARTLLMVLGGVLPIMHCAHIGAWPFRLC
QAIQGPRGAGTSGKADPRPPRTSSRAHLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE
HAQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY
DIWGNTVNVASRMDSTGVLDKIQVTEETSVILQTLGYTCTCRGIINVKGKGDLKTYFVNT
EMSRSLSQSNLTS
NT seq 2742 nt   +upstreamnt  +downstreamnt
cttccaacctggcttcaggagcggctgctgctgtccctgctgccggcacacatagccatg
gagatgaaagcggagatcatccagaggctgcagggccccaaagccggccagatggagaac
accaacaacttccacaacctctacgtcaagcggcacaccaacgtcagtatcctctatgcg
gacattgttgggttcacccgtctggccagtgactgctcccctggagagctcgtccatatg
ctgaatgaactctttggaaagttcgatcaaattgcaaaggagaatgaatgcatgagaata
aaaattttaggagactgctactactgtgtgtccggactgcctatatctctccctaaccat
gccaagaattgtgtgaaaatgggactggatatgtgtgaagccataaagaaagtgagggac
gccaccggagtggacatcaacatgcgcgtgggagtgcattctgggaacgtgctgtgcggc
gtgatcgggctgcagaagtggcagtacgacgtgtggtcacatgacgtcaccctggccaac
cacatggaagctggaggggtccctggacgtgttcacatttcttctgttaccctgcaacac
ttgaatggagcttacaaagtggaagaaggcgatggtgacatcagagacccgtatttaaag
caacatttggtgaaaacttactttgtaatcaaccccaagggagagcggcggagccctcag
cacctctttaggcctcgacacacccttgacggagcgaagatgagggcttctgtccgcatg
acccggtacctggagtcctggggggcggccaagccctttgcacacctgcatcacagagac
agcatgactacggagaacggcaagatcagcaccacggatgtaccaatgggtcagcataat
tttcaaaatcgcaccttaagaaccaagtcacaaaagaaaagatttgaagaggaattaaat
gaaaggatgattcaagcaattgatggaatcaatgcacaaaagcaatggctcaagtccgaa
gacattcagagaatctcattgcttttctacaataaaataatagaaaaagaataccgagcc
accgcactgccggccttcaagtattacgtgacttgcgcttgcctgatcttcttctgcatc
tttatcgtgcaggttctggtcttacccaaaacgtccattctcggaatttcctttggagcg
gcgtttctctcacttgcctttatccttttcgtctgctttgctggacagcttttgcaatgc
agcaagaaagcatctgcttctctcctgtggcttttaaagtcatcgggcatcatcgccaac
cggccctggcctcggatctccctgacggtcatcaccacggccatcatattgaccatggcc
gtgttcaatatgtttttcctgagtgactcagaggaaacaattcttccgactgccaacgcg
tccaacacaagtctttctggcgcaagtaaccaggcagcaattctgcgtgcgcaaaatttg
tttttcctgccgtactttatatacagctgcatccttgggctgatctcctgttccgtcttc
ctgcgtgtgaattacgagctgaagatgctgatcatgatggcagccttggtgggctacaac
accatcttcctccacactcacgctcccctcctggacgactacagccaggtcctgttcgag
agaccaggcatttggaaagacctaaagaccatgggctcagtatctctctttatatttttc
atcacactgcttgttctgggaagacagaatgaatattactgtaggttagacttcttatgg
aagaacaagttcaaaaaagagcgggaggagatagaaaccatggagaacttgaaccgagtg
ctgctggagaacgtgcttcctgcgcacgtggctgagcacttcctggcgcggagcctgaag
aacgaggggcaagttaatgctggtagttcagaggggcgcacatcctgccacgcagtgggc
attcagtcagtgctggcggttgtcctgtgcattcttgtcatcatcaccattccccagagg
gtcacttcggctgatgtcagcagatgccagggaaacgcaagaactctcctcatggttctt
ggtggagtgcttcccatcatgcactgcgcccacattggcgcctggccattccgcctgtgt
caggccatccaagggccccgaggagccggcaccagtggaaaagcagatccccggcccccc
aggaccagctcccgcgcccacctgctctccaagccgaagttcagtggtgttgaaaagatc
aagaccatcggcagcacgtacatggcagcgacaggtctgagcgcggtgcccagccaggag
cacgcccaggagccggagaggcagtacatgcacattggcaccatggtggagtttgcattt
gccctggtggggaagctggatgccatcaacaagcactccttcaatgacttcaagttacga
gtaggtattaaccatggccctgtcatagccggtgtgattggagctcagaagccgcagtat
gacatctggggcaacaccgtcaatgtggccagcaggatggacagcaccggagtcctggac
aaaatccaggtgacagaggagacgagcgtcatcctacagaccctaggctacacgtgcacg
tgtcggggaatcatcaacgtgaaaggaaagggggacctgaagacctacttcgtcaacacg
gagatgtcacggtccctttctcagagcaacctgacctcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (50)   
   KEGG PATHWAY (50)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (70)   

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